Magdalena Wilczyńska-Borawska

Publications of Magdalena Wilczyńska-Borawska

• Prosthetic status and treatment needs for lost masticatory function in haemodialysis patients.

  Authors: Magdalena Wilczyńska-Borawska, Jolanta Małyszko, Dorota Cylwik-Rokicka, Michał Myśliwiec

  Archives of medical science : AMS. 02/2012; 8(1):81-7.

  Premature loss of permanent teeth leads to stomatognathic system disability. It is a very serious but underrated problem for patients with chronic renal failure. The aim of study was analyse thePremature loss of permanent teeth leads to stomatognathic system disability. It is a very serious but underrated problem for patients with chronic renal failure. The aim of study was analyse the degree of loss of masticatory function and number of teeth present for haemodialysis patients, and to define patients' needs for prosthetic treatment, which could restore correct occlusal condition. Sixty-nine haemodialysis patients treated at the Nephrology and Transplantology Clinic with the Dialysis Centre at the Medical University of Bialystok, Poland. We checked: 1) the total number of teeth and number of teeth separately for upper and lower jaws, 2) the existing prosthetic restorations and 3) the preserved masticatory function. More male than female patients were in possession of full dentition.All patients with at least 28 natural teeth with retained occlusal contacts whilst chewing were males (4; 10% males; 5.7% of the whole group). There were 15 edentulous patients: 7 males (10%) and 8 females (11.5%). Hundered percent of female patients presented with various degrees of tooth loss and needed prosthetic treatment. Nearly 70% of tested haemodialysis patients did not have a reconstructed masticatory function. The population of haemodialysis patients from the North East part of Poland are patients with severe stomatognathic system dysfunctions. It is of importance for dentists, as well as nephrologists, to understand the essence of the problem, as the general health of a patient cannot be improved without ensuring functional comfort of such as important system as the masticatory one.

• [Salivary phosphate-binding chewing gum--an integrative approach to chronic kidney disease and oral diseases].

  Authors: Magdalena Wilczyńska-Borawska, Jacek Borawski, Wanda Stokowska

  Przegla̧d lekarski. 01/2011; 68(9):633-6.

  The course and treatment of chronic kidney disease (CKD) is adversely affected by numerous metabolic disarrangements, comorbid states and general diseases, i.e. hyperphosphatemia and metabolic boneThe course and treatment of chronic kidney disease (CKD) is adversely affected by numerous metabolic disarrangements, comorbid states and general diseases, i.e. hyperphosphatemia and metabolic bone disease, chronic inflammation, accelerated atherosclerosis (partly of infectious etiology) and devastating cardiovascular disease. Furthermore, CKD patients are usually afflicted by multiple oral abnormalities, including troublesome oral dryness and the very aggressive form of periodontal disease. The use of chitosan-containing chewing gum in CKD subjects seems to offer a novel therapeutic approach of interdisciplinary importance: the chitosan binds salivary phosphates and, when swallowed, likely phosphates in the alimentary tract, thus beneficially lowering blood phosphate levels, while the gum itself increases impaired salivary flow and has a potent oral antimicrobial activity. Thus, it effectively improves general oral hygiene and prevents progression of periodontal disease being (besides of hyperphosphatemia) one of the established causes of atherosclerosis development/progression. The undemanding maneuver of chewing the chitosan-containing, phosphate-binding gum has a potential to diminish excessive morbidity in CKD patients.

• [Oral cavity changes in patients after kidney transplantation and preventive-treatment algorithms].

  Authors: Magdalena Wilczyńska-Borawska, Jolanta Małyszko, Wanda Stokowska

  Przegla̧d lekarski. 01/2010; 67(12):1322-4.

  Kidney transplantation is the best option of treatment for patients with end-stage renal failure. However, following kidney transplantation many stomatological abnormalities are frequently reported.Kidney transplantation is the best option of treatment for patients with end-stage renal failure. However, following kidney transplantation many stomatological abnormalities are frequently reported. It is mainly due to immunosuppressive therapy and subsequent impaired immune response. There is an increased risk of infections and malignancies. The most frequent findings in the oral cavity include: aphthae, erosions of bacterial, viral and fungal origin, lichen-like or leukoplakia-like changes. The another type of change is gingival hyperplasia and its periodontologial consequences. In this review etiology, clinical symptoms of periodontological changes are described together with algorithm of pre- and posttransplant management of oral healthy is provided.

• Dental problems in a potential kidney transplant recipient: case report and literature review.

  Authors: Magdalena Wilczyńska-Borawska, Joanna Bagińska, Jolanta Małyszko

  Annales Academiae Medicae Stetinensis. 01/2010; 56(2):51-4.

  Renal failure is associated with many abnormalities in the oral and dental health status. The aim of this study was to describe dental treatment procedures in a patient on the waiting list for kidneyRenal failure is associated with many abnormalities in the oral and dental health status. The aim of this study was to describe dental treatment procedures in a patient on the waiting list for kidney transplantation. We treated a 46-year-old female with ESRD due to reflux nephropathy who was dialyzed peritoneally for 8 years. She received a cadaveric kidney transplant in 2003. Her immunosuppression consisted of prograf, MMF, and steroids. Creatinine after Tx was 1.58 mg/dL rising to 2 mg/dL 6 months later. Transplant biopsy in 2005 (creatinine 3.5 mg/dL) revealed chronic thrombotic microangiopathy. Four years after Tx she entered the PD program to eliminate odontogenic foci of infection. Pantomography and digital radiography disclosed the presence of three teeth classified as potential centers of inflammation. The methods of treatment were: (1) surgical extraction with filling of the bone defect with BioOss bone substitute material and application of Bio-Gide collagen membrane; (2) extirpation of inflamed pulp under anaesthesia; (3) antiseptic endodontic treatment. Clinical and radiologic examination revealed normal bone healing and normal condition of periapical tissues. Elimination of odontogenic centers of inflammation in patients before kidney transplantation should be the goal of a precisely planned multi-specialist treatment. Prevention of odontogenic inflammation must be started as soon as possible in the pre-dialysis period since periodontal diseases are a significant cause of generalized inflammation accelerating progression of atherosclerosis and its complications.

• The periodontal status of pre-dialysis chronic kidney disease and maintenance dialysis patients.

  Authors: Jacek Borawski, Magdalena Wilczyńska-Borawska, Wanda Stokowska, Michał Myśliwiec

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 03/2007; 22(2):457-64.

  BACKGROUND: Periodontitis contributes to generalized inflammation and development of systemic diseases, including atherosclerosis and cardiovascular disease. Its extent in maintenance haemodialysisBACKGROUND: Periodontitis contributes to generalized inflammation and development of systemic diseases, including atherosclerosis and cardiovascular disease. Its extent in maintenance haemodialysis (HD) patients is disputable and not known in continuous ambulatory peritoneal dialysis (CAPD) and pre-dialysis chronic kidney disease (CKD) patients. METHODS: One hundred and six patients (35 on HD, mean age, 56 years; 33 on CAPD, mean age 51 years; and 38 pre-dialysis CKD stage 2-5, mean age 51 years) from north-eastern Poland were enrolled. Dialysis subjects were recruited from a cohort of 141 HD and 61 CAPD patients. Two control groups comprised 26 generally healthy individuals with advanced periodontitis requiring specialized treatment, and 30 subjects from general population. Gingival index (GI), papillary bleeding index (PBI), plaque index (PI), loss of clinical attachment level (CAL) and community periodontal index of treatment needs (CPITN) were determined according to WHO recommendations. RESULTS: Average values of the indices in HD, CAPD, pre-dialysis CKD, advanced periodontitis and general population subjects were as follows: GI-1.37, 0.95, 1, 2 and 1; PBI-1.45, 0, 0, 2.20 and 1; PI-2.05, 1.59, 1, 2 and 1; and CAL loss-5.11, 3.47, 2.50, 4.68 and 1.40 mm, respectively. CPITN, analysed separately as community periodontal index and periodontal treatment needs, further indicated a high severity of periodontitis in all renal failure groups as compared with general population subjects. The disease was most advanced in maintenance HD patients-comparable to the full-symptomatic form of periodontitis; then it was successively diminished in CAPD and pre-dialysis CKD subjects. CONCLUSIONS: Periodontal disease is prevalent, severe and under recognized in renal failure patients. Prophylaxis and early dental treatment should be intensified in these subjects, and may be of interdisciplinary importance.

• [Periodontal disease and atherosclerosis: an underestimated link?]

  Authors: Magdalena Wilczyńska-Borawska, Wanda Stokowska

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. 10/2003; 15(87):281-3.

  Periodontal disease is a common bacterial and destructive disorder of oral tissues. We reviewed epidemiological and experimental to data studies demonstrating close associations between chronicPeriodontal disease is a common bacterial and destructive disorder of oral tissues. We reviewed epidemiological and experimental to data studies demonstrating close associations between chronic periodontitis and development of generalized inflammation, vascular endothelial injury, and atherosclerosis. Periodontal disease has been convincingly emerging as an important independent cardiovascular risk factor. It deserves timely treatment also as a likely part of primary prevention of ischemic heart disease, stroke, and peripheral vascular disease.