Luis F. Mota

University of Texas Health Science Center at Houston, Houston, Texas, United States

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Publications (6)14.9 Total impact

  • Raul G. Caffesse · Luis F. Mota · Edith C. Morrison
    Periodontology 2000 02/2007; 9(1):7 - 13. DOI:10.1111/j.1600-0757.1995.tb00051.x · 3.63 Impact Factor
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    ABSTRACT: Periodontitis is characterized by the formation of periodontal pockets and bone loss. Although the basic treatment emphasizes the control of bacterial plaque, the clinician is confronted with the need to correct soft and/or hard tissue defects that develop as a consequence of the disease. This article reviews the current status of regenerative approaches in treating soft and hard tissue defects (based mainly on findings from our own laboratory) and assessed the global applicability of these procedures. Many different techniques have been suggested to treat those defects with, in general, a high degree of success. From the present knowledge it can be concluded that periodontal soft and hard tissue regeneration is possible. Treatment of areas with localized gingival recession or insufficient keratinized gingiva can be achieved with soft tissue grafts or pedicle flaps, as well as with the use of dermal allografts. The treatment of hard tissue defects around teeth and implants can be approached using different types of bone grafts, guided tissue or bone regeneration, or a combination of these. The predictability of many of these therapies, however, still needs to be improved. Since most of these techniques are sensitive, specific, and expensive, their present universal application is limited.
    American journal of dentistry 11/2002; 15(5):339-45. · 0.85 Impact Factor
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    ABSTRACT: A genetic polymorphism in the interleukin 1 gene has been implicated as a factor in determining the severity of adult periodontitis. Among white Europeans, the prevalence of genotype-positive subjects has been reported to be around 30%. The purpose of this study was to assess the prevalence of genotype-positive individuals in a Hispanic population. Fifty Mexicans were evaluated for their interleukin 1 genotype with a commercially available test. Subjects were divided into groups, as determined by their genotype (positive or negative), and were then analyzed according to age, sex, and smoking habits. Thirteen of 50 subjects were genotype positive, a prevalence of 26%. The most common polymorphisms found in genotype-positive subjects were allele 1.2 for the IL 1A gene and allele 1.2 for the IL 1B gene. When only subjects older than 30 years were evaluated, the prevalence of genotype-positive individuals was 31%. The prevalence of genotype-positive subjects in a Hispanic population was 26%, similar to the prevalence found among ethnic populations from or descended from Northern, Central, and Southern Europe.
    Quintessence international 04/2002; 33(3):190-4. · 0.95 Impact Factor
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    ABSTRACT: The aim of this study was to evaluate the effectiveness of a new bioresorbable barrier alone or in combination with BioOss for guided bone regeneration around dental implants with exposed implant threads. Five adult Macaca fascicularis monkeys were used in this investigation. After extraction of all premolars and first molars, two endosteal oral implants were installed in each quadrant and the bony defects were randomly treated with either: 1) placement of the new bioresorbable device alone (group 1); 2) placement of the new bioresorbable barrier in combination with BioOss (group 2); 3) placement of an ePTFE barrier in combination with BioOss (group 3); or (4) control (group 4). After a period of six months the animals were killed and the histological processing was performed. There was a significant difference in the amount of new bone regeneration around the implants between the four groups (i.e. groups 1, 2, 3 and 4) (P=0.0122). There was no difference, however, between group 2 and group 3. It can be concluded that the new bioresorbable barrier in combination with BioOss appears to obtain the same results in this type of bony defects as the grafting material in combination with an ePTFE barrier.
    International Journal of Oral and Maxillofacial Surgery 09/1998; 27(4):315-20. DOI:10.1016/S0901-5027(05)80623-X · 1.57 Impact Factor
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    ABSTRACT: The aim of this investigation was to evaluate clinically and histologically a new custom-made, root analogue titanium implant placed into extraction sockets in monkeys (Macaca fascicularis). Three adult monkeys were used in this investigation. After raising full thickness flaps on the buccal and lingual side, the upper central and lateral incisors were extracted. Each tooth root was machine copied to 1 titanium analogue using a new CAD/CAM-system. The implants were installed in the respective extraction sockets and the flaps sutured back. After 6 months of healing biopsies were taken and processed according to the cutting-grinding technique. The percentage of mineralized bone-to-implant contact was measured as a fraction of the rough implant surface using computer-assisted analysis. The main clinical problem that occurred during implant placement was the fracture of the buccal alveolar wall. The histometric evaluation showed a mean mineralized bone-to-implant contact of 41.2 +/- 20.6%. In this investigation it could be shown that implants fabricated by laser copying will osseointegrate. The presented data encourage the performance of clinical and experimental trials evaluating the new system utilizing improved second generation CAD/CAM equipment. Such studies are currently underway.
    Clinical Oral Implants Research 11/1997; 8(5):386-92. DOI:10.1034/j.1600-0501.1997.080505.x · 3.89 Impact Factor
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    ABSTRACT: Abstract The purpose of this study was to compare the clinical results of guided periodontal tissue regeneration (GPTR) using a resorbable barrier manufactured from a copolymer of polylactic and polyglycolic acids (Resolut® Regenerative Material) with those of non-resorbable e-PTFE barrier (Gore-Tex® Periodontal Material). 12 subjects participated, 6 with similarly paired class II furcations and 6 with 2 similar 2,3-wall periodontal lesions. The resorbable and non-resorbable barriers were randomly assigned to 1 defect in each subject. Non-resorbable barriers were removed in six weeks. Plaque index (PII), gingival index (GI), probing depth (PD), clinical attachment level (CAL) and gingival recession (R) were recorded at baseline, (i.e., immediately prior to surgery) and at 12 months postsurgically. The clinical healing was similar and uneventful in both groups. Intrabony pockets depicted significant changes from baseline (p < 0.05) for probing depth reduction and gain in clinical attachment levels. No differences were found between treatments. Class II furcations showed significant improvements from baseline (p < 0.05) for probing depth reduction and clinical attachment gain. No differences were detected between treatments. It is concluded that the resorbable barrier tested is as effective as the nonresorbable e-PTFE barrier for the treatment of class II furcations and intrabony defects.
    Journal Of Clinical Periodontology 09/1997; 24(10):747 - 752. DOI:10.1111/j.1600-051X.1997.tb00192.x · 4.01 Impact Factor