Jan Mosters

Publications of Jan Mosters

• Sequence-based typing of flaB is a more stable screening tool than typing of flaA for monitoring of Campylobacter populations.

  Authors: Alexander Mellmann, Jan Mosters, Edda Bartelt, Peter Roggentin, Andrea Ammon, Alexander W Friedrich, Helge Karch, Dag Harmsen

  Journal of clinical microbiology. 11/2004; 42(10):4840-2.

  Different typing schemes for Campylobacter spp. were evaluated with 70 outbreak and sporadic isolates. The discriminatory indexes were 0.944 (by pulsed-field gel electrophoresis), 0.920 (byDifferent typing schemes for Campylobacter spp. were evaluated with 70 outbreak and sporadic isolates. The discriminatory indexes were 0.944 (by pulsed-field gel electrophoresis), 0.920 (by genotyping of the flagellin A gene), 0.902 (by genotyping of flaB), and 0.886 (by multilocus sequence typing). Cross-classification gave 94.77 or 95.82% (PFGE-flaA or PFGE-flaB) concordance. flaA was overdiscriminatory in three cases, most probably due to intragenomic recombination.