[Show abstract][Hide abstract] ABSTRACT: The most common tumors derived from the mesenchyme of the gastrointestinal system are stromal tumors. These tumors are typically seen in the stomach and small intestine and less frequently in the colon, rectum and esophagus and are very rarely located outside the gastrointestinal system. Cure is provided with complete surgical resection with resection borders free of tumor. Tumor size, mitotic index, localization, CD117 and CD34 negativity in immunohistochemical studies, mucosal ulceration and presence of necrosis help to predict recurrence of the illness and patient survival. In high-risk gastrointestinal stromal tumors (GISTs) there is an increased rate of recurrence and shortened survival despite complete surgical resection. Thus patients with a high-risk GIST should be given adjuvant therapy with imatinib mesylate. Sunitinib maleate is another FDA-approved agent only for cases who cannot tolerate imatinib or who are resistant to it. Herein we present three cases with GISTs in different locations of the gastrointestinal system with a review of the relevant literature.
Case Reports in Gastroenterology 01/2010; 4(2):250-260.
[Show abstract][Hide abstract] ABSTRACT: Thyroidal hemiagenesis resulting from the failure of development of one thyroidal bud to develop accounts for fewer than 0.1% of thyroidal disorders necessitating surgery. This rare congenital anomaly usually occurs on the left side. Any nonfunctional lobe detected by scintigraphy needs to be evaluated further by ultrasonography, because thyroid hemiagenesis is associated with varying degrees of morbidity when it coexists with other anomalies requiring surgical intervention. We report the case of a 38-year-old woman with preoperatively diagnosed thyroidal hemiagenesis, who underwent surgery in our clinic. We review the literature in relation to this case, and discuss the problems and complications associated with this unusual congenital anomaly.
Surgery Today 02/2004; 34(5):437-9. · 1.21 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: A patient with blunt abdokminal trauma due to a traffic accident was admitted to our clinic and operated urgently because of hemodynamic shock. Operative exploration revealed rupture of a congenital giant cavernous liver hemangioma, then a partial hepatic resection was performed. Liver abscess and pleural effusion occurred in the postoperative period and the abscess was drained by a CT- guided cathetei: However the catheter drainage get infected. As a conclusion, if a liver hemangioma is detected incidentally on routine check-up studies, these people, carrying potential risk ofrupture should be warned about high risk jobs.
Ulusal travma dergisi = Turkish journal of trauma & emergency surgery: TJTES 08/2002; 8(3):176-8.
[Show abstract][Hide abstract] ABSTRACT: The patient (male; age = 69) was referred to the Department of 1st Surgery upon suspicion of obstructive jaundice. He was admitted to the Department of Internal Medicine with back pain, loss of appetite, and jaundice and some laboratory tests were performed. He has no history of alcohol use. During his physical examination, pain was noted in the upper right quadrant and the gall bladder was palpable and hydropic. A 22 mm. cystic structure with smooth contours was detected in the abdominal CT scan. An exploratory laparatomy was planned. During the perioperative cyst aspiration, the laminar membrane of hydatic cyst led to the probable diagnosis of hydatic cyst. Cholecystectomy, choledochoduodenostomy, partial cystectomy and capitonnage was performed. The patient was started on 800 mg/day albendazole during postoperative period and then was discharged.
Ulusal travma dergisi = Turkish journal of trauma & emergency surgery: TJTES 05/2001; 7(2):126-8.
[Show abstract][Hide abstract] ABSTRACT: SüleymanDemirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 2001 Aralık; 8(4) Primer hiperparatiroidizmde cerrahi tedavi ve sonuçlan Ahmet Kocakuşak, Orçun Oral Şentürk, Haldun Sunar, Soykan Arıkan, Muzaffer Akıncı Özet Bu çalışmada primer hiperparatiroidizm nedeni ile 1996-2002 yılları arasında cerrahi servisimizde ameliyat edilen 11 hastanın tedavi sonuçlarını literatür eşliğinde değerlendirdik. Olguların tamamı kadın olup, ortalama yaş 52.7(40-73 yaş arası değişen şekilde)'idi. Ortalama takip süresi 9.2 aydır (3-16 ay arası değişen şekilde). Semptomların ortaya çıkışı ile tara arasında geçen süre ortalama 22.4 aydır(4-48 ay arası değişen şekilde). Tüm hastalarda osteodistrofik değişiklikler mevcuttu.Asemptomatik hastamız yoktu. Ameliyat öncesi lokalizasyon çalışmaları arasında ultrasonografi(USG), manyetik rezonans görüntüleme (MRI) ve Tc-sesta MIBI 99m sintigrafisine (Sg) yer verildi.Onbir hastamızın dokuzuna bir cerrahi girişim yeterli olurken,bir hastamızda ameliyat sonrası patolojinin lenf nodulu ile uyumlu gelmesi diğer bir hastamızda ise piyesin normal ektopik tiroid dokusu olduğu şeklinde rapor edilmesi üzerine bu iki hastaya mükerrer cerrahi girişim uygulanması gerekmiştir. Sonuç olarak ülkemizde primer hiperparatiroidizm henüz yeterince dikkat çekmeyen bir hastalık olup hastaların taraşı nadiren asemptomatik evrede konabilmektedir. Buna karşın batı kaynaklı literatürlerde öpere edilen hastaların büyük çoğunluğu asemptomatiktir. Asemptomatik hastalarda oluşabilecek komplikasyonlarla baş edebilmek güç olduğu için bu tür hastalara dahi cerrahi önerilmelidir. Hastalar ameliyat sonrası kendilerini daha iyi hissetmekle birlikte /semptomlarından tamamen arınmaları nadirdir. Tüm bunlara rağmen hiperparatiroidizmde cerrahi vazgeçilmez tedavi modalitesidir. Anahtar Kelimeler: Primer hiperparatiroidizm,görüntüleme yöntemleri,semptomlar. Abstract Abstract Surgıcal treatment and results of pnmary hyperparathyroıdısm in this study we aimed to evaluate the results of surgical treatment of 11 patients who were treated for pri-mary hyperparathyroidism and followed up in the outpatient clinic of our hospital between 1996-2002. Ali the patients were women with a mean age of 52.7(between 40-73 years).The mean follow-up time was 9.2 months(between 3-16 months).The mean period of time since onset of symptoms tül diagnosis was 22.4 months(between 4-48 months). Ali the patients had osteodystrophic changes.There were not any asympto-matic patient in our study group. Preoperative localisation studies included ultrasonography(USG) ,magnetic resonance imaging (MRI) and Tc -sesta MIBI 99m scintigraphy (Sg). One staged initial operation was enough in 9 patients,whereas a second operation was needed in 2 patients. in conclusion, primary hyperparathyroidism is stili an underestimated disease in Turkey and patients are rarely asymptomatic due to delayed diagnosis. According to the western literatüre however, most of the patients are reported to be asymptomatic. Patients do feel better but they are rarely free of symptoms after surgery. Surgery should be offered even to the asymptomatic patients, because the treatment of possible future complications might be extremely dif-ficult. Although these outcomes, surgery stili remains as the only treatment modality for primary hyperparathyroidism. Key Words: Primary hyperparathyroidism,imaging studies,symptoms.