Gülsen Okten

Publications (2)3.55 Total impact

• Article: The Mayer-Rokitansky-Kuster-Hauser and gonadal dysgenesis anomaly in a girl with 45,X/46,X,del(X)(p11.21).

  Ayla Güven, Nurten Kara, Yaman Sağlam, Sezgin Güneş, Gülsen Okten
  American Journal of Medical Genetics Part A 02/2008; 146A(1):128-31. · 2.39 Impact Factor
• Article: Germ cell tumor showing partial trisomy 1 in a gonadectomized intersex child with monosomy X and double Y mosaicism.

  Gönül Ogur, Faruk Güçlü Pinarli, Ayhan Dağdemir, Sevilhan Artan, Ender Artürk, Murat Elli, Ozlem Türkeli Sezer, Gülsen Okten
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  ABSTRACT: High incidence of germ cell tumors arising from dysgenetic gonads in patients with sexual chromosome abnormalities has been described, especially in patients with a Y chromosome bearing cell line. Here we report a 14-year-old patient with ambiguous genitalia. Constitutional karyotype showed 45,X/46,X,derY [?t(Yp;Yq)] mosaicism. The patient developed an abdominally located mixed malignant germ cell tumor 5 years after the removal of the dysgenetic gonads. Tumor karyotype showed partial trisomy 1q, a derivative 8q, and a hyperdiploidy with +X, +7, +12, +15, +19, +21, and an unidentified marker.
  Journal of Pediatric Hematology/Oncology 12/2006; 28(11):750-4. · 1.16 Impact Factor