[Show abstract][Hide abstract] ABSTRACT: Our objective was to investigate the potential risk factors associated with cytomegalovirus (CMV) infection.
From January 1999 to December 2001, 163 liver transplantations were performed in 154 patients. The study inclusion criteria were absence of retransplantation and survival of more than 6 months. One hundred fifteen patients met the inclusion criteria. We determined variables such as age, gender, and number of hemecomponents as well as serum IgG CMV status of donors and recipients. We recorded the immunosuppression used by each patient. CMV infection was detected by positive antigenemia.
Recipient mean age was 50 years. The etiology of cirrhosis was viral (n = 57; 49.6%), alcoholic (n = 20; 17.4%), virus and alcohol (n = 15; 13.0%), cryptogenic (n = 14; 12.2%), or other causes (n = 9; 7.8%). CMV infection was positive in 75 patients (65.8%). There was no relation between infection and age, gender, or CMV IgG donor recipient status, or the number of hemecomponent units. The risk was 3.8-fold higher for patients receiving a three-drug compared with a two-drug regimen. When cyclosporine was used instead of tacrolimus, the risk of CMV infection was 4.3-fold higher. Logistic regression analysis revealed cyclosporine (OD=5.8) and a three-drug regimen (OD=6.7) to have stronger associations with CMV infection.
The use of cyclosporine (OD=5.8) and a three-drug regimen (OD=6.7) are risk factors for CMV infection.
[Show abstract][Hide abstract] ABSTRACT: Cytomegalovirus (CMV) is one of the most common and serious opportunistic infections in solid organ transplant patients. In different series the incidence of CMV infection ranges from 25% to 85%. An indirect effect of infection includes reduced long-term patient and allograft survival. Our objective was to determine the relationship between CMV infection and patient survival after orthotopic liver transplantation.
From January 1999 to December 2001, 163 orthotopic liver transplantations were performed in 154 patients. The inclusion criteria for this analysis were the absence of retransplantation and survival of more than 6 months. One hundred fifteen patients met the inclusion criteria. CMV infection was detected by positive antigenemia.
CMV infection occurred in 65.8% of patients after orthotopic liver transplantation. Their 5-year survival was 85%, with no difference observed between patients with or without infection (P = .8).
CMV infection did not interfere with patient survival after orthotopic liver transplantation.
[Show abstract][Hide abstract] ABSTRACT: This paper deals with the human consequences caused by modes of working and managing in the restructuring of banking work. It analyzes the mobility transferences of place and/or position of employees submitted to restructuring in a public banking institution and presents the consequences of restructuring from the viewpoint of the bank workers. It is a case study, whose data were collected from corporate documents, personal interviews and semi-structured interviews in 1998 and 2003. Data received statistical and content analysis. Results indicate that the restructuring of banking work caused mobility in different manners. The worst effects were on the senior employees and on those who had more length of service, since they descended in the hierarchy. The main human consequences were the instability in work stability, involuntary nomadism, short-term relationships, break of trust and psychic suffering.
Revista de Administração de Empresas 03/2006; 46(1):27-40. DOI:10.1590/S0034-75902006000100004 · 0.21 Impact Factor