Franco Garibaldi

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Publications (4)1.79 Total impact

  • Source
    Article: New devices for imaging in nuclear medicine.
    Roberto Pani, Rosanna Pellegrini, Maria Nerina Cinti, Carlo Trotta, Paolo Bennati, Margherita Betti, Giuseppe De Vincentis, Francesco Cusanno, Franco Garibaldi, Stefano Ridolfi, Stan Majewsky, Benjamin M W Tsui
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    ABSTRACT: Pinhole gamma camera imaging offers the ability to obtain high resolution images from single gamma ray emitting radiotracers playing a reasonable tradeoff between very small field of view (FoV) and sensitivity. On the other hand the total spatial resolution of a pinhole imaging device is predominantly affected by the detector intrinsic spatial resolution for reduced magnification factors. To design very compact pinhole SPET scanners with very high intrinsic spatial resolution, authors investigated a miniature gamma camera based on the newly developed Hamamatsu H8500 flat panel photomultiplier. The PSPMT was coupled to the following scintillation arrays: CsI(Tl) array with 0.2-mm, 1-mm, 1.4-mm pixel size and NaI (Tl) with 1-mm pixel size. The imaging performances were evaluated by 57Co spot and flood irradiations. NaI(Tl) array shows a better pixel identification for 1 mm pixel size, proving to be a good candidate to make a large area photodetector based on multi PSPMTs closely packed. Although CsI(Tl) array had the smallest pixel size, the low light output limited the best intrinsic spatial resolution to about 0.5 mm.
    Cancer Biotherapy and Radiopharmaceuticals 03/2004; 19(1):121-8. · 1.79 Impact Factor
  • Article: Tumor SNR Analysis in Scintimammography
    Maria Nerina Cinti, Roberto Pani, Rosanna Pellegrini, Claudio Bonifazzi, Raffaele Scaf, Franco Garibaldi, Francesco Cusanno, Renato Campanini, Nico Lanconelli, Ro Riccardi, Alberto Del Guerra, Senior Member
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    ABSTRACT: A new gamma camera dedicated to scintimammography (single photon emission mammography---SPEM) now has a full-breast field of view. One can clinically examine a mildly compressed breast with a cranio-caudal-like projection as one would in X-ray mammography. This camera is based on pixelated scintillation arrays and position sensitive photomultiplier tubes. By reducing the collimator-tumor distance, we enhanced the geometric spatial resolution and the contrast. Unfortunately, due to the low counting rates in scintimammography, low contrast images are usually seen, particularly with small tumors.
    11/2003;
  • Article: Tumor SNR Analysis in Scintimammography by
    Maria Nerina Cinti, Roberto Pani -member Ieee, Rosanna Pellegrini, Claudio Bonifazzi, Raffaele Scaf, Franco Garibaldi, Francesco Cusanno, Renato Campanini, Nico Lanconelli, Ro Riccardi, Alberto Guerra-senior, Member Ieee
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    ABSTRACT: The introduction of a new gamma camera fully dedicated to scintimammography (Single Photon Emission Mammography--SPEM), and more recently with a full breast FoV, allowed to make clinical examination in cranio-caudal projection like in RXmammography, with breast mildly compressed. Such cameras are based on pixellated scintillation array and position sensitive photomultiplier (PSPMT). Reducing the collimator-tumor distance, the geometric spatial resolution and contrast was enhanced. Unfortunately, due to the scintimammographic low counting, poor contrast images are still obtained, in particular for small tumor.
    12/2002;
  • Article: Tumor SNR Analysis in Scintimammography by Dedicated High Contrast Imager
    Maria Nerina Cinti, Roberto Pani -member Ieee, Rosanna Pellegrini, Claudio Bonifazzi, Raffaele Scaf, Franco Garibaldi, Francesco Cusanno, Renato Campanini, Nico Lanconelli
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    ABSTRACT: The introduction of a new gamma camera fully dedicated to scintimammography (Single Photon Emission Mammography--SPEM), and more recently with a full breast FoV, allowed to make clinical examination in cranio-caudal projection like in RXmammography, with breast mildly compressed. Such cameras are based on pixellated scintillation array and position sensitive photomultiplier (PSPMT). Reducing the collimator-tumor distance, the geometric spatial resolution and contrast was enhanced. Unfortunately, due to the scintimammographic low counting, poor contrast images are still obtained, in particular for small tumor. The aim of this paper is to evaluate how a camera based on pixellated detector can improve the SNR values for small tumor by an effective correction of the spatial response. The procedure is based on good pixel identification. A Small Gamma Camera (SGC) was arranged using metal channel dynode PSPMT photomultiplier (Hamamatsu R7600-C8) coupled to different CsI (Tl) scintillator array, with field of view (FoV) with an all purpose collimator. This PSPMT kind drastically reduces the charge spread improving the intrinsic characteristics of the imager. The dimensions of the CsI (Tl) arrays were the same of PSPMT active area (22x22mm 2 ). Considering the very high intrinsic spatial resolution, a look up table was realized to accurately correct the gain and spatial non-uniformities. We used a breast and torso phantom to characterize the SNR as a function of scintillation pixel size, thickness of the breast, tumor size and depth. The data showed that the SNR depends principally on the match between the tumor and pixel size. In particular, for a 6 mm diameter tumor, the best SNR results were obtained by a 2x2 mm 2 pixelled array. For larger tumors, up to 10 mm di...
    12/2001;
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