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American Journal of Hematology 07/2006; 44(3):213 - 214. · 4.67 Impact Factor
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International Journal of Hematology 11/2002; 76(3):290-1. · 1.27 Impact Factor
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ABSTRACT: We describe a case of thoracic aortic aneurysm complicated by chronic disseminated intravascular coagulation (DIC). Initially the DIC was controlled successfully by administration of gabexate mesilate and dalteparin. However, because these drugs were given intravenously, the patient could not be discharged. Subsequently, the DIC was treated successfully by changing to orally administered camostat mesilate, warfarin and aspirin, which allowed the patient to leave hospital.
[Rinshō ketsueki] The Japanese journal of clinical hematology 04/2002; 43(3):199-203.
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ABSTRACT: We report a case of 13-year-old boy with grouwh failure following allogeneic bone marrow transplantation which was performed at the age of 6 for acute lymphoblastic leukemia. The patient had been preconditioned with total body irradiation,. Growth failure was observed in height and body weight, and growth hormone (GH) deficiency was confirmed by the endocrinological studies. The patient was successfully treated by replacement therapy with recombinant GH without recurrence of leukemia, the duration of administration being short and only for 1 year and 6 months.
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ABSTRACT: A 16-year-old Japanese male with acute mixed lineage leukemia in the second remission underwent allogeneic bone mallow transplantation from a HLA-identical sibling donor. Atypical choleccystitis developed three weeks after transplantation. Abdominal ultrasound examination revealed maked thickening of the gallbladder wall without biliary sludge or gallstones. Cholecystitis was treated by the cessation of cycloporine A three days after symptoms development. To our knowledge, this is the first report of a patient with cyclosporine A induced cholecystitis, that may have been due to direct injury to the gallbladder wall and not a cholestatic mechanism.
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ABSTRACT: Bone marrow transplantation cells were separated by continuous cetrifugation with a Fenwal CS-3000 Plus Blood Cell Speparator. This procedure has been performed by automatic processing of bone marrow aspirate in a closed sterile system, without the use of density gradient, and took approximately 1 hour for processing 500 ml of bone marrow aspirate. The recovery of the mononuclear cells was 17.8±10.0% of the total nucleated cells, with negligible red cell and granulocyte contamination, allowing the subsequent freezing to be carried out directly. Hematological recovery after autologous bone marrow transplantation was prompt with these cells, and took 14 days. This method of separation of mononuclear celle is suitable for use in ABO-incompatible allogeneic and in autologous bone marrow transplantation.
