E De Pedri

Publications (2)3.54 Total impact

• Article: [Use of Severini's coaxial catheters in gastrointestinal interventional radiology].

  G Cozzi, M Bellomi, L F Frigerio, C Morosi, A Pestalozza, E De Pedri, A Di Finizio, A Severini
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  ABSTRACT: The growing importance of gastrointestinal interventional radiology has led to the development of new instruments and materials for the different proposed purposes. The authors present a set consisting of two coaxial catheters which was created for percutaneous transhepatic biliary drainage (Severini set). Its easy handling, adaptability and tolerability make it a versatile instrument in the hands of interventional radiologists for positioning large-calibre catheter (9-14 F) in deep sites. Hereafter are reported the results in 29 patients treated with different therapeutic aims and the use of the set for different pathologies. The catheters allowed a complete resolution of the collections communicating with the gastrointestinal tract in 4 of 5 patients. The catheter was inserted as a feeding tube in 22 patients. Finally, it was used as a gastrostomy catheter in 2 patients. Neither early nor late complications due to insertion or use of this set were observed.
  La radiologia medica 07/1990; 79(6):607-9. · 1.44 Impact Factor
• Article: In vivo study of polyurethane-coated Gianturco-Rosch biliary Z-stents.

  A Severini, S Mantero, M C Tanzi, A Cigada, F Addis, G Cozzi, M Salvetti, S Andreola, A Motta, E Regalia, A Pulvirenti, E De Pedri, R Doci
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  ABSTRACT: Prototypes of Gianturco-Rosch Z-stents coated with polycarbonate urethane (PCU) were placed in the biliary tree of pigs, in order to test their biomechanical behavior, stability, and biocompatibility. The stents were surgically implanted in the common bile duct of three pairs of pigs, which were killed after 1, 3, and 6 months respectively. Explanted livers from pigs of the same race, age, and size were used to provide comparative data. The bile ducts were radiologically and histopathologically examined; the stents were processed and examined by scanning electron microscopy. No complications occurred and the animals showed a normal weight gain. The main bile duct appeared radiologically and macroscopically dilated, but the stents proved to be in place. Histologically, the bile duct epithelium was destroyed, but neither hyperplastic nor inflammatory fibrotic reactions of the wall were evident. Both the metallic structure and the polymeric coating of the stents were intact. A layer of organic material with a maximum thickness of approximately 3 micron was evident on the inner surface of the stents. Conclusion: The present in vivo study demonstrates the biocompatibility, efficacy, and stability of PCU-coated Gianturco-Rosch stents in the biliary environment.
  CardioVascular and Interventional Radiology 22(6):510-4. · 2.09 Impact Factor