Barbara Posch

University of Cambridge, Cambridge, ENG, United Kingdom

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Publications (7)8.25 Total impact

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    ABSTRACT: A 14-year-old male domestic shorthair cat presented with an acute onset of aggressive behaviour, fear and hypersalivation. Neurological examination revealed bilateral mydriasis and left-sided facial twitching and hemiparesis. Magnetic resonance imaging (MRI) showed moderate bilateral symmetrical T2-hyperintensity along the entire hippocampus and bilateral asymmetric T2-hyperintensity in the pyriform lobes. Marked bilateral contrast enhancement of the hippocampus was evident on post-contrast T1-weighted images. The partial complex seizures were refractory to medical treatment and the cat was euthanased 4 days after admission. The clinical and MRI findings were consistent with feline hippocampal necrosis (FHN). On histopathology, neuronal necrosis and astrocytosis were present in the hippocampi and pyriform lobes. In addition, an oligodendroglioma was detected in the right pyriform lobe. Contrary to previous reports of FHN in which no underlying cause could be identified, we believe that in this case the seizure focus arose from a neoplastic lesion within the right pyriform lobe. This unique case report represents the so-called 'dual pathology' of temporal lobe epilepsy in humans, in which an extrahippocampal lesion within the temporal lobe results in hippocampal sclerosis.
    Journal of feline medicine and surgery. 07/2012;
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    ABSTRACT: Incomplete ossification of the humeral condyle (IOHC) is characterized by an intracondylar fissure located where the intercondylar physis is present in growing dogs. Its radiologic and computed tomographic features have been described but the magnetic resonance (MR) features have not been characterized. Our purpose was to further describe the range of MRappearances of IOHC, to assess the diagnostic capability of MRrelative to radiology, and to determine whether MRis able to identify the disease before a fissure forms. Thirty-eight elbow MRscans and radiographs, when available, were reviewed and divided into three groups. In Group 1 (affected elbows, n = 22), there was an intracondylar defect on MRwith variable appearance; the defect was not visible radiographically in 32% of the elbows. The main difference between Group 2 (nonaffected elbows, n = 6) and Group 3 (contralaterals to IOHC or to condylar fracture, without fissure, n = 10) was the appearance of the humeral condyle in short tau inversion recovery (STIR) sequences: all elbows in Group 2 had a homogeneous humeral condyle, whereas all but one in Group 3 were heterogeneous. One dog in Group 3 developed a complete condylar fissure 7 months after the first examination, when no evidence of an intracondylar defect had been detected. The MRappearance of IOHC is variable and a heterogeneous humeral condyle in STIR images without a clear defect may warn of the possibility for the subsequent development of a condylar fissure.
    Veterinary Radiology &amp Ultrasound 05/2012; 53(5):560-5. · 1.41 Impact Factor
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    ABSTRACT: A nine-month-old entire female terrier cross was presented with intermittent anorexia, vomiting and recent onset of abdominal pain and distension. A diagnosis of unilateral hydronephrosis was made following ultrasound examination and intravenous urography, but no cause was identified. Subsequent ureteronephrectomy and histology of the affected kidney showed ureteric atresia as the cause of obstruction. Uterus unicornis was also identified and ovariohysterectomy was performed. The combination of structural abnormalities can be explained by an in-utero developmental error of their common embryological precursor, the mesonephric duct.
    Journal of Small Animal Practice 08/2011; 52(8):441-4. · 1.18 Impact Factor
  • Barbara Posch, Jane Dobson, Mike Herrtage
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    ABSTRACT: Feline acromegaly is characterized by chronic excessive growth hormone secretion, most commonly caused by a functional pituitary adenoma. In this study, acromegaly was diagnosed in 15 cats on the basis of compatible clinical signs, laboratory, and magnetic resonance imaging (MRI) findings. MRI findings were reviewed retrospectively. Enlargement of the pituitary gland with suprasellar extension was present in all cats. No characteristic signal patterns were identified on T1-weighted and T2-weighted sequences. Contrast enhancement was nonuniform in all cats, as was suspected involvement of the adjacent hypothalamus. A mass effect on the cavernous sinus and third ventricle was present in 13 cats. Mild peritumoral edema was present in four cats, and moderate edema in one cat. Transtentorial herniation was present in one cat. Histopathology confirmed the presence of a pituitary adenoma in two cases. MRI is a useful modality to establish the diagnosis of acromegaly.
    Veterinary Radiology &amp Ultrasound 03/2011; 52(4):422-7. · 1.41 Impact Factor
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    ABSTRACT: The os penis in the cat has not been described radiographically, as compared with the dog. However, a small linear bony radiopacity is sometimes detected in the perineal area of male cats. We hypothesized that the feline os penis might be visible on survey radiographs of the pelvis, and we aimed to investigate the frequency of its visualization using analog and computed radiography (CR) system. One hundred radiographs of the pelvis of 99 male cats were reviewed retrospectively (50 were obtained with a CR system and 50 with an analog system). Age, breed, neutering status, and reason for presentation were recorded, as well as the visualization of the os penis. An os penis was detected in 19/50 (38%) cats with CR and in eight of 50 (16%) cats with analog radiography; this difference was statistically significant. With CR, the median age of cats with a visible os penis was significantly higher than in cats where the os penis was not seen. In one cat with a visible os penis examined with CR and analog radiography, the os penis was only visible on CR images. The penile tissues were examined histopathologically in one cat and well-differentiated bone was found but there were no pathologic findings detected in surrounding tissues. Thus, the os penis can be detected on radiographs of cats and this should not be mistaken for a pathologic finding such as urolithiasis or dystrophic mineralization.
    Veterinary Radiology &amp Ultrasound 01/2011; 52(3):270-2. · 1.41 Impact Factor
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    ABSTRACT: Currently, there are no available anatomic descriptions of the soft tissue structures that are visible with ultrasound in the canine tarsus. Eight cadaver hindlimbs and 10 clinically normal dogs (15-37 kg) were examined with ultrasound to establish which structures could be visualized in normal dogs. The structures always identified included the long digital extensor tendon, the tibialis cranialis tendon, the joint space, and the three bellies of the extensor digitum brevis muscle on the cranial/dorsal aspect of the tarsus. The lateral digital extensor tendon and the peroneus longus tendon were identified as a single structure on the lateral aspect of the tarsus. The caudal/plantar approach allowed identification of the calcaneal tendon, the deep and superficial digital flexor tendons, the plantar ligament, and the lumbricales and interosseus muscles. The medial collateral ligament can be identified on the medial tarsus of larger dogs. This technique has proved useful in the diagnosis of soft tissue injuries of the canine tarsus, and clinical examples of tibialis cranialis tendinopathy, deep digital flexor tendinopathy, fibrosis surrounding the medial collateral ligament and extent of invasion of a tarsal hemangiosarcoma are described.
    Veterinary Radiology &amp Ultrasound 01/2009; 50(3):304-8. · 1.41 Impact Factor
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    ABSTRACT: The jejunal lymph nodes of 57 dogs without clinical signs of gastrointestinal disease were examined to characterize their ultrasonographic appearance on B-mode and power Doppler examination, and to obtain ultrasonographic measurements. The lymph nodes were mildly hypoechoic to the mesentery in 71% of dogs and isoechoic in 29%. All dogs, 6 years of age or older had jejunal lymph nodes of uniform echogenicity. In dogs less than 6 years of age, nonuniform lymph nodes with different echopatterns were observed. Although most lymph nodes had no blood flow based on power Doppler examination, hilar blood flow was detected in 33% of dogs, which were generally less than 2 years of age. The median maximum thickness of the jejunal lymph nodes was 3.9 mm (range 1.6-8.2 mm), and their median maximum width 7.5 mm (range 2.6-14.7 mm). There was a significant correlation between larger lymph node diameter and younger age and higher body weight. We concluded that patient age should be considered when interpreting the echopattern and vascularity of jejunal lymph nodes in dogs, and that the jejunal lymph nodes of dogs without clinical signs of gastrointestinal disease may exceed the previously stated upper limit of 5-6 mm thickness.
    Veterinary Radiology &amp Ultrasound 01/2009; 50(2):195-200. · 1.41 Impact Factor