[Show abstract][Hide abstract] ABSTRACT: The relationship between red cell catalase activity and glucose concentrations was examined. Red cell catalase activity, whole blood glucose concentration, red cell lysate glucose concentration and packed cell volume (PCV) were estimated in 40 diabetic patients and a control group of 30 healthy subjects. The diabetic group had a significantly lower catalase (p<0.01) activity than the control. As would be expected, the blood glucose concentration of the diabetic group was significantly higher (p<0.01) than that of the control group. Same was observed for the red cell lysate glucose concentration. There was no significant difference in the packed cell volume of both groups (p<0.01). Red cell catalase correlated negatively and significantly with red cell lysate glucose (r = -0.29, p<0.05); in the diabetic subjects. There was no significant correlation of red cell catalase with either the red cell lysate glucose concentration (r = 0.088; p>0.05) or with the blood glucose concentration (r = -0.130; p>0.05) in the control group. The findings above suggest that raised red cell glucose may exhaust red cell catalase. Low level of red cell catalase in diabetics may be a risk factor for the complications of diabetes mellitus.
[Show abstract][Hide abstract] ABSTRACT: The pattern of dietary habits and how this affected glycemic control in diabetics in Eastern Nigeria was investigated. In this study, about 48% of the diabetic patients` diets used plantain as the only carbohydrate source while 52.4% took diets that included various sources of carbohydrate but at reduced levels. There was no significant difference (p>0.05) between the glycemic control of both groups as judged by their glycated hemoglobin levels. However, subjects using multiple carbohydrate sources had significantly higher BMI (p< 0.05) than those on plantain. We conclude that multiple food sources, if well regulated, would control diabetes and find better acceptance among diabetics than a single carbohydrate source.