Publications (2)3.74 Total impact
Article: Consequences of right ventricle-to-pulmonary artery shunt at the first stage for the Fontan operation.[show abstract] [hide abstract]
ABSTRACT: The evidence of the advantageous physiology associated with right ventricle-to-pulmonary artery (RV-PA) shunt in the early postoperative period after the Norwood procedure for hypoplastic left heart syndrome has been recently widely reported. We investigated the late consequences of this modification from the perspective of the third-stage palliation, the Fontan operation. Between September 1995 and November 2006, a consecutive series of 50 children with hypoplastic left heart syndrome from a single institution underwent a fenestrated Fontan operation (lateral tunnel technique): group 1 (n = 19) after the modified Blalock-Taussig shunt, and group 2 (n = 31) after RV-PA shunt during the Norwood procedure. Hemodynamic, echocardiographic, electrocardiographic, and clinical operative and perioperative data were analyzed. Children after the RV-PA shunt were characterized by higher preoperative partial oxygen tension in pulmonary arteries (p = 0.018) and the aorta (p = 0.028), as well as lower systolic, diastolic, and mean aortic pressure (p = 0.005, p = 0.004, p = 0.019). After administration of 100% oxygen, this group additionally showed a lower value for systemic resistance (p = 0.013). The analyzed angiograms revealed a higher incidence of systemic-to-pulmonary collateral vessels (p = 0.003) in group 2. At the discharge after Fontan operation, children after the RV-PA shunt demonstrated higher arterial partial oxygen tension (p = 0.004). The two groups did not differ significantly with respect to the mortality, ventricular function, incidence of pleural effusions or rhythm disturbances, intensive care unit stay, and hospitalization time. The Norwood procedure with the RV-PA shunt provides satisfactory late hemodynamics. Children who underwent this method of palliation were more prone to the development of systemic-to-pulmonary arterial collaterals.The Annals of thoracic surgery 12/2007; 84(5):1611-7. · 3.74 Impact Factor
Article: [Pediatric open heart surgery on cardiopulmonary bypass without the use of blood products].[show abstract] [hide abstract]
ABSTRACT: Pediatric open heart surgery is associated with the usage of cardiopulmonary bypass. The circuit is primed with blood products because of risk of excessive hemodilution. The aim of the study was to prove the safety of open heart surgery on cardiopulmonary bypass without the use of blood products in the pediatric group. In this study, 78 patients with atrial septal defect (ASD type II) were enrolled and underwent elective atrial septal defect repair between the years of 1999 and 2003. The group I included 37 children aged from 3 to 16 years (8.79 +/- 4.45) who weighed from 13 to 68.8 kg (29.93 +/- 15.00). In this group, the transfusion of blood products during the surgery and postoperative course was avoided. Blood products were used in a control group (group II 4.1 patients) both during and after surgery. Children from this population ranged in age from 2.5 to 17 years (8.41+/- 4.18) and weighed from 11.5 to 59.7 kg (26.99 +/-12.95). For statistical analysis the t-Student test and U Mann Whitney test were used. The length of stay in the intensive care unit (1.18 +/- 0.47 vs 1.20 +/- 0.61 days) and total hospital stay (8.91 +/- 3.05 vs 10.05 +/- 4.28 days) did not differ statistically between the groups. Values of haematocrit and hemoglobin levels were statistically lower in group I during the postoperative course compared to the control group (intraoperative Hct: 19.43 +/- 4.93 vs 23.37 +/- 4.68%, p < 0.001), but these levels did not correlate with the occurrence of hypoxic, neurologic or coagulation complications. Directly after the surgery, group I had significantly higher platelet and leucocyte counts compared to the control group. There were no differences between the confronted populations in regard to postoperative bleeding (4.61 +/- 2.24 vs 4.76 +/- 1.75 ml/kg). The avoidance of using blood products in pediatric patients during open heart surgery with cardiopulmonary bypass is found to be safe, is not correlated with an increased surgical risk, and does not result in a prolonged hospital stay.Przegla̧d lekarski 02/2004; 61(3):146-51.