[Show abstract][Hide abstract] ABSTRACT: Alopecia areata (AA) is a chronic inflammatory disease which predominantly affects young people and causes hair loss. The disease requires therapeutic management, psychological support and occasional hospitalization. The objective of this analytic case-control study was to evaluate health related quality of life (HRQL) in patients with AA compared to healthy people. The data were collected from 57 patients with AA and 57 healthy people. A Persian version of SF-36-item questionnaire was employed for measuring HRQL. The result of the study revealed a significant difference in mean ranks of global HRQL (P<0.0001) especially in the following parameters: role function, feeling, global health perception and sleep status. Based on multivariate regression, the patients' gender and job were found to affect their quality of life. Psychological support of the patients with AA in addition to their medical therapy is highly recommended.
World Applied Sciences Journal 01/2012; 18(5):689-692. · 0.23 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: Permethrin, a pyrethroid insecticide, is not yet available in Iran and may be a useful substitute for the control of scabies in Iran.
To compare the efficacy of topical lindane with topical permethrin in the treatment of scabies in a population in Iran.
In a double-blind, randomized study, all consecutive patients with scabies were randomized into two groups. One group and their family contacts received 1% lindane cream, and the other group and their family contacts were treated with topical 5% permethrin cream. Subsequently, patients were followed up at 2- and 4-week post-treatment.
Of the 99 patients enrolled in the study, 47 patients received 1% lindane cream, and 52 patients were treated topically with 5% permethrin cream. Permethrin provided an improvement rate of 84.6% after two weeks, whereas lindane was effective only in 48.9% of patients.
Permethrin (5%) cream was found to be significantly more effective in the treatment of scabies in comparison with lindane in this study, and it seems that it could be an alternative treatment.
Indian Journal of Dermatology Venereology and Leprology 01/2006; 72(1):33-6. · 1.21 Impact Factor