A M Gendel'man

Publications (6)0.35 Total impact

• Article: [Comparison of the clinical and hemodynamic effects of nitroglycerin, isosorbide dinitrate and isosorbide-5-mononitrate in acute myocardial infarction].

  L B Lazebnik, S N Tereshchenko, A M Gendel'man
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  ABSTRACT: One hundred and eighty patients with acute myocardial infarction (MI) were followed up. The patients were divided into 3 groups: (1) those receiving glyceryl trinitrate (GTN) (n = 43); (2) those on isosorbide dinitrate (ISDN) (n = 66); (3) those on isosorbide-5-mononitrate (IS-5-MN) (n = 71). In all the groups, the drugs were given by long-term continuous oligovolumic infusion. Following 24 hours of administration, 66.7, 47.3, and 17.1% increases in infusion rates were required in 74.4, 72.7, and 26.8% of the patients from Groups 1, 2, and 3, respectively. All the agents produced a pronounced antianginal effect and resulted in alleviated acute left ventricular failure. The in-hospital mortality rates were 16.2, 16.7, and 12.7% in Groups 1, 2, and 3, respectively. GTN, ISDN, and IS-5-MN caused adverse effects in 4.7, 18.2, and 2.8% of the patients from Groups 1, 2, and 3, respectively.
  Kardiologiia 11/1991; 31(10):13-5. · 0.20 Impact Factor
• Article: [Use of ultrasonic inhalation of isoket in patients with ischemic heart disease associated with chronic obstructive bronchitis].

  L B Lazebnik, S N Tereshchenko, A M Gendel'man, E A Lesniak, A S Donina
  Sovetskaia meditsina 02/1991;
• Article: [Treatment of pulmonary edema with bolus administration of 0.1% nitroglycerin solution].

  S N Tereshchenko, A M Gendel'man, L B Lazebnik, N O Gushanskaia, E A Lesniak, A Iu Dvorianchikov
  Sovetskaia meditsina 02/1991;
• Article: [Correction of disorders of left-ventricular contractility in acute myocardial infarction by infusion of nitroglycerin solution].

  Iu K Tokmachev, L B Lazebnik, S N Tereshchenko, A M Gendel'man, E A Lesniak
  Sovetskaia meditsina 02/1990;
• Article: [The treatment of acute myocardial infarct with perlinganit].

  L B Lazebnik, S N Tereshchenko, A M Gendel'man
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  ABSTRACT: As many as 43 patients with myocardial infarction were under observation. There were 30 men and 13 women aged 36 to 82 years. Of these, 26 patients had large-focal and 17 transmural myocardial infarction. Perlinganit was injected in the form of 0.1% solution by means of a drug-dosing apparatus (DDA-1). The drug infusion lasted 51.1 +/- 4.8 h on the average, the mean infusion rate was 74.5 +/- 3.4 micrograms/min. After 24 hours it was required that in 32 patients the mean infusion rate be increased 1.5-fold. The hemodynamics was assessed with the aid of tetrapolar chest rheography. Well-defined clinical and hemodynamic effects were revealed. In some patients, the clinical signs of left ventricular insufficiency could be eliminated. Contractile function of the left ventricle returns to normal within the first hours of disease. During perlinganit treatment, the antianginal and antiarrhythmic effects were recorded. The data obtained point to the fact that the use of perlinganit for the treatment of acute myocardial infarction is advisable.
  Terapevticheskii arkhiv 02/1990; 62(8):26-8. · 0.14 Impact Factor
• Article: [Treatment of acute myocardial infarction by prolonged continuous infusion of nitroglycerin].

  Iu K Tokmachev, L B Lazebnik, A M Gendel'man, S N Tereshchenko, E A Lesniak, M Kh Sheremet'ev
  Sovetskaia meditsina 02/1990;