Publications (9)9.49 Total impact
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Article: [Definition, diagnosis and therapy of chronic widespread pain and so-called fibromyalgia syndrome in children and adolescents. Systematic literature review and guideline].
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ABSTRACT: The scheduled update to the German S3 guidelines on fibromyalgia syndrome (FMS) by the Association of the Scientific Medical Societies ("Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften", AWMF; registration number 041/004) was planned starting in March 2011. The development of the guidelines was coordinated by the German Interdisciplinary Association for Pain Therapy ("Deutsche Interdisziplinären Vereinigung für Schmerztherapie", DIVS), 9 scientific medical societies and 2 patient self-help organizations. Eight working groups with a total of 50 members were evenly balanced in terms of gender, medical field, potential conflicts of interest and hierarchical position in the medical and scientific fields. Literature searches were performed using the Medline, PsycInfo, Scopus and Cochrane Library databases (until December 2010). The grading of the strength of the evidence followed the scheme of the Oxford Centre for Evidence-Based Medicine. The formulation and grading of recommendations was accomplished using a multi-step, formal consensus process. The guidelines were reviewed by the boards of the participating scientific medical societies. The diagnosis FMS in children and adolescents is not established. In so-called juvenile FMS (JFMS) multidimensional diagnostics with validated measures should be performed. Multimodal therapy is warranted. In the case of severe pain-related disability, therapy should be primarily performed on an inpatient basis. The English full-text version of this article is available at SpringerLink (under "Supplemental").Der Schmerz 06/2012; 26(3):318-30. · 0.88 Impact Factor -
Article: German evidence and consensus based guidelines 2010 for the treatment of juvenile idiopathic arthritis (JIA)
Pediatric Rheumatology 05/2012; 9:1-1. · 1.44 Impact Factor -
Article: Fibromyalgiesyndrom bei Kindern und Jugendlichen
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ABSTRACT: FragestellungErstellung einer interdisziplinären Leitlinie auf S3-Niveau zur Diagnostik und Therapie des juvenilen Fibromyalgiesyndroms (JFMS) in Kooperation von 10 medizinischen bzw. psychologischen Fachgesellschaften und 2 Patientenselbsthilfeorganisationen. MethodikEine Literatursuche nach allen kontrollierten Studien zur Therapie des FMS wurde unter Benutzung der Cochrane Collaboration Reviews (1993–12/2006), Medline (1980-12/2006), PsychInfo (1966–12/2006) und Scopus (1980–12/2006) durchgeführt. Die Vergabe von Evidenzklassen erfolgte mittels des Systems des Oxford Centre for Evidence-Based Medicine. Empfehlungsgrade wurden nach der Empfehlungsgraduierung der nationalen Versorgungsleitlinien vergeben und in einem mehrstufigen nominalen Gruppenprozess erstellt. ErgebnisseSchmerzen bei Kindern/Jugendlichen in mehreren Körperregionen mit einer Dauer >3 Monaten ohne erkennbare somatische Ursache werden als juveniles FMS (JFMS) oder als „Schmerzverstärkungssyndrom“ (SVS) bezeichnet. Ein multimodales Konzept mit psycho- und physiotherapeutischen Verfahren, Entspannungstherapien und Schulungsprogrammen wird empfohlen (Empfehlungsgrad offen). SchlussfolgerungDiese Leitlinien werden zu einer besseren Erkennung und standardisierten Versorgung von JFMS-Patienten beitragen und die Durchführung klinischer Studien erleichtern. ObjectiveThe aim was to develop a guideline for diagnostic procedures and treatment of juvenile fibromyalgia syndrome (JFMS) in cooperation with 10 German medical and psychological associations and 2 patient self-help groups. MethodsA systematic literature search, including all controlled studies evaluating diagnosis and treatment of JFMS, was performed in the Cochran Collaboration Reviews (1993–12/2006), Medline (1980-12/2006), PsychInfo (1966–12/2006) and Scopus (1980–12/2006). Levels of evidence were assigned according to the classification system of the Oxford Centre for Evidence-Based Medicine. Grading of the strengths of recommendations was performed according to the German program for disease management guidelines. Standardized procedures to reach a consensus on recommendations were used. ResultsPain in children/adolescents involving several body areas and lasting >3 months without an obvious somatic cause is called JFMS or pain amplification syndrome. Therapeutically, a multidisciplinary concept with psychotherapy and physiotherapy, relaxation techniques and patient education is recommended. ConclusionThese guideline will contribute to a better recognition and standardized care of patients with JFMS and facilitate clinical studies.Der Schmerz 04/2012; 22(3):339-348. · 0.88 Impact Factor -
Article: Psychotherapie bei Patienten mit Fibromyalgiesyndrom
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ABSTRACT: FragestellungEine interdisziplinäre Leitlinie zur Therapie des Fibromyalgiesyndroms (FMS) wurde in Kooperation von 10 medizinischen bzw. psychologischen Fachgesellschaften und 2 Patientenselbsthilfeorganisationen erstellt. MethodikEine Literatursuche über alle kontrollierten Studien zur Therapie des FMS mit psychologischen bzw. psychotherapeutischen Verfahren wurde unter Benutzung der Cochrane Collaboration Reviews (1993–12/2006), Medline (1980–12/2006), PsychInfo (1966–12/ 2006) und Scopus (1980–12/ 2006) durchgeführt. Für die Vergabe von Evidenzklassen wurde das System des Oxford Centre for Evidence-Based Medicine verwendet, für die Vergabe von Empfehlungsgraden die Empfehlungsgraduierung der nationalen Versorgungsleitlinien. Die Erstellung der Empfehlungen erfolgte in einem mehrstufigen nominalen Gruppenprozess. ErgebnisseDie zeitlich befristete Anwendung kognitiver und operanter Verhaltenstherapie erhielt den EmpfehlungsgradA und die zeitlich befristete Verwendung von Hypnotherapie/geleitete Imagination und therapeutischen Schreiben den EmpfehlungsgradB. SchlussfolgerungenAuf FMS-Subgruppen zugeschnittene Behandlungsverfahren sollten entwickelt und untersucht werden. BackgroundA guideline for the treatment and diagnostic procedures in fibromyalgia syndrome (FMS) was developed in cooperation with 10 German medical and psychological associations and 2 patient self-help groups. MethodsA systematic literature search including all controlled studies of evaluated multicomponent therapy was performed in the Cochrane Collaboration Reviews (1993–12/2006), Medline (1980–12/2006), PsychInfo (1966–12/2006) and Scopus (1980–12/ 2006). Levels of evidence were assigned according to the classification system of the Oxford Centre for Evidence-Based Medicine. Grading of the strengths of recommendations was done according to the German program for disease management guidelines. Standardized procedures to reach a consensus on recommendations were used. ResultsCognitive and operant behavioral therapy is strongly recommended (grade A). Guided imagery/hypnotherapy and written emotional disclosure are recommended (grade B). ConclusionsPsychotherapeutic programs tailored to FMS subgroups should be developed and tested.Der Schmerz 04/2012; 22(3):295-302. · 0.88 Impact Factor -
Article: Evidence-based, interdisciplinary guidelines for anti-inflammatory treatment of uveitis associated with juvenile idiopathic arthritis.
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ABSTRACT: Uveitis in juvenile idiopathic arthritis (JIA) is frequently associated with the development of complications and visual loss. Topical corticosteroids are the first-choice therapy, and immunosuppression is commonly used. However, treatment has not been standardized. Representatives from the German Ophthalmological Society, Society for Childhood and Adolescent Rheumatology, and the German Society for Rheumatology reached consensus on a standardized treatment strategy according to disease severity in the individual patient. The recommendations were based on a systematic literature analysis in MEDLINE and consensus expert meetings. Evidence and recommendations were graded, and an algorithm for anti-inflammatory treatment and final statements confirmed in a Delphi method. An interdisciplinary, evidence-based treatment guideline for JIA uveitis is presented.Rheumatology International 11/2011; 32(5):1121-33. · 1.88 Impact Factor -
Article: [Evidence and consensus based treatment guidelines 2010 for juvenile idiopathic arthritis by the German Society of Paediatric Rheumatology].
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ABSTRACT: Treatment of Juvenile Idiopathic Arthritis (JIA) has improved quality of life in children and adolescents with JIA. Standardisation of care offers the chance to improve the quality of care of those patients. New studies have been published after completion of our last treatment guideline (2007). An updated consensus process is mandatory. A systematic literature analysis in PUBMED (key words: juvenile idiopathic (rheumatoid) arthritis, therapy; limits: humans, published in the last 3 years, all child 0-18 years, clinical trial) revealed 17 relevant studies. Studies relating to diagnosis of JIA, Uveitis, vaccination, transition were excluded. Representatives nominated by scientific societies and organisations were invited to consensus conferences which were hosted by a professional moderator. The following societies were invited: Berufsverband der Kinder- und Jugendärzte (BVKJ), Deutsche Gesellschaft für Kinder- und Jugendmedizin (DGKJ), Deutsche Gesellschaft für Rheumatologie (DGRh), Deutsche Ophthalmologische Gesellschaft (DOG), Deutsche Rheuma-Liga Bundesverband, Verein zur Förderung und Unterstützung rheumatologisch erkrankter Kinder und deren Eltern, Vereinigung für Kinderorthopädie, Zentraler Verband der Physiotherapeuten und Krankengymnasten (ZVK). Consensus conferences were each attended by more than 95% of the nominated representatives. Consensus statements were confirmed by nominal group technique and Delphi method. Updated consensus statements regarding drug therapy, symptomatic and surgical management of JIA were compiled and judged strictly by the criteria of Evidence-Based Medicine (EBM).Klinische Pädiatrie 11/2011; 223(6):386-94. · 1.77 Impact Factor -
Article: [Juvenile fibromyalgia syndrome].
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ABSTRACT: The aim was to develop a guideline for diagnostic procedures and treatment of juvenile fibromyalgia syndrome (JFMS) in cooperation with 10 German medical and psychological associations and 2 patient self-help groups. A systematic literature search, including all controlled studies evaluating diagnosis and treatment of JFMS, was performed in the Cochran Collaboration Reviews (1993-12/2006), Medline (1980-12/2006), PsychInfo (1966-12/2006) and Scopus (1980-12/2006). Levels of evidence were assigned according to the classification system of the Oxford Centre for Evidence-Based Medicine. Grading of the strengths of recommendations was performed according to the German program for disease management guidelines. Standardized procedures to reach a consensus on recommendations were used. Pain in children/adolescents involving several body areas and lasting >3 months without an obvious somatic cause is called JFMS or pain amplification syndrome. Therapeutically, a multidisciplinary concept with psychotherapy and physiotherapy, relaxation techniques and patient education is recommended. These guideline will contribute to a better recognition and standardized care of patients with JFMS and facilitate clinical studies.Der Schmerz 07/2008; 22(3):339-48. · 0.88 Impact Factor -
Article: [Psychotherapy in patients with fibromyalgia syndrome].
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ABSTRACT: A guideline for the treatment and diagnostic procedures in fibromyalgia syndrome (FMS) was developed in cooperation with 10 German medical and psychological associations and 2 patient self-help groups. A systematic literature search including all controlled studies of evaluated multicomponent therapy was performed in the Cochrane Collaboration Reviews (1993-12/2006), Medline (1980-12/2006), PsychInfo (1966-12/2006) and Scopus (1980-12/ 2006). Levels of evidence were assigned according to the classification system of the Oxford Centre for Evidence-Based Medicine. Grading of the strengths of recommendations was done according to the German program for disease management guidelines. Standardized procedures to reach a consensus on recommendations were used. Cognitive and operant behavioral therapy is strongly recommended (grade A). Guided imagery/hypnotherapy and written emotional disclosure are recommended (grade B). Psychotherapeutic programs tailored to FMS subgroups should be developed and tested.Der Schmerz 07/2008; 22(3):295-302. · 0.88 Impact Factor -
Chapter: Krankheitsbewältigung im Alltag
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ABSTRACT: Die Bewältigung einer Krankheit verläuft immer individuell und altersbedingt.12/2007: pages 565-586;
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