Publications (3)5.26 Total impact
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ABSTRACT: Radiation therapy for breast cancer can cause pulmonary damage. This was diagnosed in two patients aged 75 and 57 years respectively. They had different types of radiation pneumonitis. The first patient presented with a so-called bronchiolitis obliterans organizing pneumonia (BOOP), four months after radiation therapy. Characteristic in BOOP are the bilateral and migrating lung infiltrates that are distributed predominantly in the middle and lower lung zones. The second patient developed a pneumonitis that classically was confined to the area of irradiation four months after radiation therapy. The two types of radiation pneumonitis can be treated successfully with corticosteroids. If symptomatic radiation pneumonitis is diagnosed early it can be treated well and than has a good prognosis.Nederlands tijdschrift voor geneeskunde 05/1999; 143(16):833-6.
Article: Detection of hydration status by total body bioelectrical impedance analysis (BIA) in patients on hemodialysis.[show abstract] [hide abstract]
ABSTRACT: The purpose of the present study was to investigate whether total body bioelectrical impedance analysis (BIA) could be appropriate to assess normohydration (i.e. dry weight) in hemodialysis patients. This study is warranted, because the simultaneous assessment of both hydration and nutritional status by BIA requires the presence of a situation of normohydration in order to guarantee valid conclusions about the nutritional analysis. Segmental bioelectrical impedance was performed to classify patients according to their hydration status. BIA measurements revealed significant differences in TBW, ECW and ICW/ECW between three hydration subgroups (under-, normo-, and overhydration), whereas ICW was similar. Therefore, TBW, ECW and ICW/ECW appear appropriate variables to assess hydration status in patients on hemodialysis. Hemodialysis diminished ECW significantly, whereas ICW did not change, suggesting that a decrease of ECW explains the fluid loss during hemodialysis.The International journal of artificial organs 08/1997; 20(7):371-4. · 1.86 Impact Factor
Article: Assessment of total body water and lean body mass from anthropometry, Watson formula, creatinine kinetics, and body electrical impedance compared with antipyrine kinetics in peritoneal dialysis patients.[show abstract] [hide abstract]
ABSTRACT: Indirect methods such as anthropometry (A), Watson formula (W), creatinine kinetics (CK), and body electrical impedance (BEI) are increasingly applied to determine total body water (TBW) and lean body mass (LBM) in dialysis patients. These methods share the disadvantage that they have been validated for healthy men only. We studied which of these four commonly applied methods can best be used routinely in CAPD patients. TBW estimates obtained from A, W, CK, and BEI were compared with those obtained by a gold standard (antypirine distribution volume, ADV) in eight CAPD patients. In addition, several BEI equations to derive lean body mass (LBM) were compared with LBM estimated by ADV in order to determine which equation is the most valuable for the assessment of LBM by BEI in CAPD patients. TBW as ADV was 41.4 +/- 6.6 (mean +/- SD) L. TBW estimated by W, A and CK underestimated ADV by a mean +/- SD of 2.3 +/- 13, 5 +/- 8.4 and 12.3 +/- 10.9% respectively. TBW as measured by BEI overestimated ADV by 2.5 +/- 8.8%. The correlation coefficients between ADV-TBW and TBW estimated by the indirect methods were r = 0.88 (A), r = 0.87 (BEI), r = 0.82 (CK), and 0.68 (W). LBM estimated by ADV was 56.7 +/- 8.9 (mean +/- SD) kg; LBM by different BEI equations ranged from 49.9 +/- 7 to 58.1 +/- 10.7 kg. The correlation coefficient between LBM by ADV and LBM according to the various BEI equations ranged from 0.81 to 0.93. A and BEI can be used to estimate TBW, but the considerable SD (or inaccuracy) makes individual predictions hazardous. Considering the correlation coefficients and difference between LBM by ADV and LBM according to different BEI equations, Deurenberg's formula can be advocated for use in the estimation of LBM by BEI.Nephrology Dialysis Transplantation 02/1997; 12(1):151-6. · 3.40 Impact Factor