[Show abstract] [Hide abstract]
ABSTRACT: A miniflow system for oxidative cyclization of alkenols with Oxone was developed. Thus, the oxidative cyclization of ( Z )- and ( E )-alkenols in i -PrOH with an aqueous solution of Oxone proceeded smoothly and safely in a PTFE tube without any exogenous catalytic species, and was subsequently quenched in a flow-reaction manner to afford the corresponding furanyl and pyranyl carbinols quantitatively within 5 or 10 min of residence time.
Beilstein Journal of Organic Chemistry 04/2009; 5. DOI:10.3762/bjoc.5.18 · 2.76 Impact Factor