Sun Ying

Publications (2)0.88 Total impact

• Article: Protective effects of combined micronutrients on islet beta-cells of streptozotocin-induced diabetic mice.

  Ying Chang, Gui-Zhen Zhang, Song-Lan Piao, Shen Gao, De-Ming Zheng, Yang Song, Anne Tsicopoulos, Sun Ying
  [show abstract] [hide abstract]
  ABSTRACT: There is a tendency for the incidence of diabetes in a population to increase with an improvement in living standards. This would imply the involvement of nutritional factors in the development of diabetes, and so nutritional considerations could be a key aspect in the research and development of an effective remedy for diabetes. In this study, combined micronutrients (selenium, vitamin E, vanadium, and chromium) were orally supplemented to streptozotocin-induced diabetic mice. Results showed that combined micronutrients could decrease the high blood glucose levels (p<0.05 or p<0.01) of diabetic mice. The protective effects of combined micronutrients on structures of beta-cells in pancreatic islets of diabetic mice were observed histopathologically and ultrastructurally. In addition, the supplementation of combined micronutrients increased insulin expression by beta-cells in pancreatic islets of diabetic mice at both translational and transcriptional levels. The immune molecular mechanisms involved were preliminarily regarded as downregulation of the expression of pathogenic T-helper 1 lymphocyte (Th1) cytokine tumor necrosis factor-alpha (TNF-alpha) (p<0.01) along with upregulation of the expression of protective T-helper 2 lymphocyte Th2 cytokine interleukin 10 (IL-10) (p<0.01) which ameliorates the Th1/Th2 imbalance in diabetes. In conclusion, supplementation of combined micronutrients to diabetic mice could effectively improve disordered glucose metabolism, protect islet structures, and improve the function of beta-cells in pancreatic islets, which are affected by differential regulation of the expression of Th1/Th2 cytokines involved in the pathogenesis of diabetes.
  International Journal for Vitamin and Nutrition Research 03/2009; 79(2):104-16. · 0.88 Impact Factor
• Conference Proceeding: Self-adjusting fuzzy controller application for linear induction motor control system

  Wang-Yuhua, Zhu-xi Lin, Dang-Zhiqian, Sun-Ying
  [show abstract] [hide abstract]
  ABSTRACT: The mathematical model of linear induction motor (LIM) based on slip frequency type vector control system is established. A self-adjusting fuzzy controller (SAFC) is designed as magnetic thrust adjuster of the motor. The speed of the motor is adjusted by control magnetic thrust of the motor. The scheme of the slip frequency type vector control system of the LIM is obtained by observing the magnetic thrust. This is the system of the closed magnetic thrust loop and the open rotor magnetic flux loop. The Simulation model of the control system has been established by Matlab/Simulink. A series of simulation experiments have been carried out in motor starting and running under the unloading and loading condition. In comparison with the PI control system, the Self-adjusting Fuzzy control system indicated that the dynamic response performance of this system is enhanced, the speed ripple is effectually decreased and the robustness of the motor control system is improved by adjusting fuzzy control rule.
  Industrial Electronics and Applications, 2008. ICIEA 2008. 3rd IEEE Conference on; 07/2008