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ABSTRACT: We describe a 15-month-old girl with acute necrotizing encephalopathy (ANE) associated with HHV-6. Inflammatory cytokines were elevated in the CSF and serum and the number of CD56bright NK cells was significantly increased in the peripheral blood. CD56bright NK cells may be involved in the pathogenesis of ANE by producing inflammatory cytokines.
Scandinavian Journal of Infectious Diseases 02/2006; 38(11-12):1122-5. DOI:10.1080/00365540600740520 · 1.64 Impact Factor