Publications (6)7.11 Total impact
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Article: High concentration (400mgI/mL) versus low concentration (320mgI/mL) iodinated contrast media in multi detector computed tomography of the liver: A randomized, single centre, non-inferiority study.
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ABSTRACT: To compare vascular and parenchymal contrast enhancement in multidetector computed tomography of the liver using two contrast media with different iodine concentration (Iodixanol 320mgI/mL and Iomeprol 400mgI/mL) and similar viscosity, using fixed total iodine volume (40gI) and iodine delivery rate (1.6gI/s). 110 patients were prospectively randomized into two groups. Group A received 125mL of Iodixanol 320 and group B 100mL of Iomeprol 400. Attenuation values were measured at the level of the aorta, portal vein and liver parenchyma on unenhanced, arterial, portal and equilibrium phases. A non inferiority test was performed on the differences between the two groups. An independent reader evaluated image quality. The equivalence of the two CM was demonstrated in all measurements. Higher, but not statistically significant, attenuation values were obtained with Iomeprol 400 in the aorta during the arterial phase (305.3HU versus 288.4HU; P=0.32) and with Iodixanol 320 in the liver parenchyma, during both portal (59.8HU versus 65.5HU; P=0.78) and equilibrium (40.4HU versus 41.8HU; P=0.55) phases. Iodixanol 320 and Iomeprol 400 injected at the same iodine delivery rate (1.6gI/s) and total iodine load (40gI) did not provide statistically significant differences in liver parenchymal and vascular contrast enhancement.European journal of radiology 06/2012; 81(11):3096-101. · 2.65 Impact Factor -
Article: The optimal contrast media policy in CT of the liver. Part II: Clinical protocols.
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ABSTRACT: The advent of multidetector computed tomography (MDCT) revolutionized abdominal imaging. In particular, the definitive assessment of CT injection protocols, for the evaluation of the liver parenchyma, is still a critical issue for radiologists. Over the last years, this feature encouraged several authors to address their efforts to find the most accurate delay between the contrast medium injection and the effective scan-start, for the identification and characterization of liver lesions. Technological developments of the present century such as number of slices, submillimetric collimation, and the use of multiple dynamic post-contrast phases per single examination, may all contribute to increase the radiation exposure of single patients. The aim of this review is to propose liver imaging protocols, taking into consideration different clinical needs such as patients with chronic liver disease, healthy patients with focal liver lesion, and oncological patients to minimize radiation exposure. Finally, two recent innovations in MDCT which illustrate the potential application of multi-energy computed tomography (MECT) and perfusion computed tomography (CTp) when evaluating liver parenchyma will be discussed in a short closing paragraph.Acta Radiologica 06/2011; 52(5):473-80. · 1.37 Impact Factor -
Article: The optimal contrast media policy in CT of the liver. Part I: Technical notes.
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ABSTRACT: Latest developments of multidetector computed tomography (MDCT), which is today considered a real volumetric technique, have revolutionized abdominal imaging. Technological improvements such as higher spatial resolution, larger volume coverage and higher temporal resolution, have reduced scan times allowing CT studies of the abdomen within a single breath-hold. Furthermore, the increased number of slices, the submillimetric collimation, and the use of multiple dynamic post-contrast phases per single examination, may all contribute to increase the radiation exposure of single patients. The aim of this review is to discuss different parameters affecting contrast media enhancement, as vascular enhancement, parenchymal enhancement and timing, in order to minimize the amount of contrast medium injected and the radiation exposure.Acta Radiologica 06/2011; 52(5):467-72. · 1.37 Impact Factor -
Chapter: Artifacts in MR-Angiography
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ABSTRACT: Artifacts represent potential pitfalls in MR-angiography: radiologists should be aware of them to prevent their appearance. They can be classified according to the mechanism responsible for their genesis. Flow Artifacts are strictly related to modification of signal intensity induced by dephasing proton mechanism when the blood flow loses the characteristic laminar pattern; they are turbulence'artifact and artefact due to saturation. Hinge artefact, typical of 3DTOF sequence, is characterized by alternating hyper-hypointense punctiform images. Geometrical artefacts are caused by wrong geometric positioning of angiographic sequence or saturation bands; they are called hypointensity linear horizontal artefact and the artefact due to non-inclusion of the vase in the excited volume. Artifacts related to wrong acquisition time with respect to contrast medium bolus arrival are maki artefact and vascular blurring. Voluntary and involuntary movement are the primary cause of patient artifacts like the gost artifact. The main artifacts from post-processing consist of the artifact from projection of the background noise and the step artifact. Magnetic susceptibility artifacts are caused by paramagnetic external substances. Finally we remember radiofrequency artifacts, due to the instability of radiofrequency or nonhomogeneity of magnetic field or instability of the the system receiver-trasmitter.12/2009: pages 27-33; -
Article: ECG-gated multidetector-row computed tomography in the assessment of left ventricular function
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ABSTRACT: An accurate quantitative and qualitative assessment of cardiac function is critical for clinical diagnosis, risk stratification, management and prognosis in patients with suspected or documented heart disease. Magnetic resonance, owing to its excellent temporal and spatial resolution, is currently considered a reference standard in the assessment of cardiac function. Multidetector-row computed tomographic scanners, with sub-second rotation times and dedicated cardiac reconstruction algorithms, have shown their ability to acquire high-resolution images suitable for coronary imaging. With retrospective ECG-gating technique, diastolic and systolic images can be produced and analyzed to assess left ventricle functional parameters. The combination of noninvasive coronary artery imaging and assessment of cardiac function with multidetector-row computed tomography is a suitable approach to a conclusive cardiac work-up in patients with suspected coronary artery disease.Imaging in medicine 12/2009; 1(2):187-194. -
Article: Adult celiac disease: MRI findings.
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ABSTRACT: The purpose of our report is to describe a spectrum of findings of celiac disease at MR enterography. MR enterography is a non-invasive, feasible, and reproducible imaging technique for the evaluation of small bowel. Findings on MR enterography, similar to those of conventional barium studies, may suggest a diagnosis of celiac disease.Abdominal Imaging 32(4):433-40. · 1.73 Impact Factor
Top co-authors
Top Journals
Institutions
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2011–2012
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Sapienza University of Rome
- Department of Radiological, Oncological and Pathological Sciences
Roma, Latium, Italy
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2009
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The American University of Rome
Roma, Latium, Italy
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