A Jovanovic

Publications (13)18.24 Total impact

• Article: [Vertical distraction osteogenesis of the extremely resorbed edentulous mandible. A retrospective description of 16 patients].

  S R Grauwen, A Jovanovic, L Amir, A G Becking
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  ABSTRACT: This study's objective is to assess long-term results of vertical distraction osteogenesis for the extremely resorbed edentulous mandible by clinically measuring and taking x-rays from the beginning of the treatment of 16 subsequent patients to its final moment in the follow up period (ranging from 2-62 months). Bone height, nerve sensitivity, complications and loss of implant were registered. Average bone resorption after 3 years was 11.2%. Out of 16 patients 5 experienced sensory nerve disturbance; 3 suffered complications. The implant success rate was 89.2%. Distraction osteogenesis appears to be a reliable technique, with which stable bone tissue is developed. Risk of sensory nerve disturbance and complications however, must be taken into consideration.
  Nederlands tijdschrift voor tandheelkunde 09/2006; 113(8):308-12.
• Article: Risk of second primary cancer following treatment of squamous cell carcinoma of the lower lip.

  I G van der Tol, J G de Visscher, A Jovanovic, I van der Waal
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  ABSTRACT: The risk of second primary cancers (excluding skin cancers) was evaluated among 56 patients who underwent treatment for a squamous cell carcinoma of the lower lip. The mean follow-up was 5.5 years. Ten patients (17.8%) developed at least one new primary cancer. The prevalence of second primary cancers within the respiratory and upper digestive tract, and elsewhere in the body, was 19.4 and 12.9 per 1000 person-years of follow-up, respectively. Patients were at risk for a second primary cancer at a steady rate of 2.7% per year during at least 5 years.
  Oral Oncology 12/1999; 35(6):571-4. · 2.86 Impact Factor
• Article: Autotransplantation of premolars. A retrospective study.

  J W Frenken, J A Baart, A Jovanovic
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  ABSTRACT: The purpose of this clinical follow-up study was to evaluate the success rate of autotransplantation of human premolars. In the period between 1982 and 1994, 46 premolars in 31 patients were transplanted. A long-term success rate of 97.5% with a mean follow-up period of 3.5 years was achieved. It seems to be justified, therefore, in selected cases, to consider the possibility of autotransplantation as a good alternative to orthodontic or prosthetic treatment, including implant insertion, when closing a gap in the dental arch.
  International Journal of Oral and Maxillofacial Surgery 07/1998; 27(3):181-5. · 1.51 Impact Factor
• Article: A modified technique to determine the desired length of bicortical screws in sagittal split osteotomies.

  A Jovanovic, J P Bouwman, D B Tuinzing
  Journal of Oral and Maxillofacial Surgery 05/1996; 54(4):528-9. · 1.64 Impact Factor
• Article: Role of genetic factors in the etiology of squamous cell carcinoma of the head and neck.

  M P Copper, A Jovanovic, J J Nauta, B J Braakhuis, N de Vries, I van der Waal, G B Snow
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  ABSTRACT: To determine the role of genetic predisposition in the etiology of head and neck squamous cell carcinoma. Retrospective study. The outpatient clinics of the departments of otorhinolaryngology and maxillofacial surgery. First-degree relatives of patients with new head and neck cancer, with first-degree relatives of the patients' spouses as controls. Occurrence of cancer of the respiratory and upper digestive tract in relatives of patients with head and neck cancer and controls. First-degree relatives (n = 617) of 105 patients with head and neck cancer had 31 cases of cancer of the respiratory and upper digestive tract vs 10 cases in the control group (n = 618) (relative risk, 3.5; P = .0002). This higher rate of cancer was even larger in siblings (16 vs 2, relative risk, 14.6; P = .0001). Genetic predisposition is an important risk factor for squamous cell carcinoma of the head and neck.
  Archives of Otolaryngology - Head and Neck Surgery 03/1995; 121(2):157-60. · 1.63 Impact Factor
• Article: [Second primary tumors following treatment of squamous cell carcinoma of the oral cavity].

  I G van der Tol, A Jovanovic, E A Schulten, P J Kostense, N de Vries, G B Snow, I van der Waal
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  ABSTRACT: In the hospital of the Free University in Amsterdam (the Netherlands) 727 patients with primary squamous cell carcinoma of the oral cavity and lip have been studied for the incidence of second primary tumors occurring in the respiratory and upper digestive tract. Out of the 727 patients, 74 (10.2%) developed a second primary tumor in these tracts. The incidence of second primary tumors was expressed per 1.000 person-years of follow-up; 28 second primary tumors per 1.000 person-years of follow-up were seen in the respiratory and upper digestive tract. The patients ran the risk of developing a second primary tumor at a steady rate of approximately 2.8% per year during at least ten years. Furthermore, an increasing incidence of second primary tumors could be observed in case of increasing use of tobacco.
  Nederlands tijdschrift voor tandheelkunde 11/1994; 101(10):403-5.
• Article: Second respiratory and upper digestive tract cancer following oral squamous cell carcinoma.

  A Jovanovic, I G van der Tol, P J Kostense, E A Schulten, N de Vries, G B Snow, I van der Waal
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  ABSTRACT: 727 patients with squamous cell carcinoma (SCC) of the lip and oral cavity have been followed for the occurrence of second primary tumours (SPTs) in the respiratory and upper digestive tract (RUDT). 74 patients (10%) developed at least one SPT in the RUDT. The incidence of SPTs was expressed per 1000 person-years of follow-up. In our study about 28 SPTs per 1000 person-years of follow-up were seen in the RUDT. Patients were at risk for a second primary tumour, at a steady rate of approximately 2.8% per year during at least 10 years. Furthermore, patients with an index tumour in the lower part of the mouth (floor of mouth, retromolar area and lower alveolar process), which is more related to tobacco and/or alcohol, seem to be more at risk for SPTs than patients with an index tumour in the other (sub)sites of the mouth.
  European Journal of Cancer Part B Oral Oncology 08/1994; 30B(4):225-9.
• Article: Risk of multiple primary tumors following oral squamous-cell carcinoma.

  A Jovanovic, I G van der Tol, E A Schulten, P J Kostense, N de Vries, G B Snow, I van der Waal
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  ABSTRACT: The follow-up of 727 patients with squamous-cell carcinoma (SCC) of the lip and oral cavity has been used for the risk analysis of multiple primary tumors (MPTs) following SCC of the lip and oral cavity. Age-, gender- and site-specific cancer-incidence rates from the general population have been applied to the appropriate persons-years of follow-up of patients with SCC of the lip and oral cavity. The study indicates that patients with a primary SCC of the lip and oral cavity have, compared with the general population, a significantly elevated risk of developing an additional cancer of the oral cavity and/or pharynx, the risk being 74.7-fold for males and 190.4-fold for females. Furthermore, a 24.6 and 45.3 times higher risk of an additional esophageal tumor was found in males and females respectively. The risk of cancer of the lung and pharynx was less elevated compared with the risk of cancer of the upper digestive tract. No elevated risks were established in organs outside the respiratory and upper digestive tract.
  International Journal of Cancer 03/1994; 56(3):320-3. · 5.44 Impact Factor
• Article: Tobacco and alcohol related to the anatomical site of oral squamous cell carcinoma.

  A Jovanovic, E A Schulten, P J Kostense, G B Snow, I van der Waal
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  ABSTRACT: The aim of the present study was to evaluate the possible relationship between tobacco smoking and alcohol drinking and the anatomical sites of squamous cell carcinoma (SCC) of the lip and oral cavity. For this purpose, a case-case study has been performed in 690 patients. The study was focused on the relative risk (RR) or developing SCC at various (sub)sites, for smokers and drinkers of alcohol (divided into moderate and heavy users) relative to non-smokers and non-drinkers. Estimates of ratios of these relative risks were obtained. The relative risk associated with tobacco smoking, adjusted for the use of alcohol, appeared to be highest for SCC in the retromolar area, followed by the floor of mouth, whereas the lowest RR was found in the cheek mucosa. For alcohol drinking, adjusted for tobacco smoking, RR of SCC of the floor of mouth was significantly higher than for the tongue, whereas the RR of SCC of the cheek appeared to be lowest. Furthermore, this study suggests that the contrasts between relative risks, observed by anatomical site of oral SCC, are more pronounced for tobacco smoking than for the use of alcohol. The possible local and systemic factors responsible for these variations of susceptibility for tobacco and alcohol within the oral cavity are discussed.
  Journal of Oral Pathology and Medicine 12/1993; 22(10):459-62. · 1.63 Impact Factor
• Article: Squamous cell carcinoma of the lip and oral cavity in The Netherlands; an epidemiological study of 740 patients.

  A Jovanovic, E A Schulten, P J Kostense, G B Snow, I van der Waal
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  ABSTRACT: The epidemiological data of 740 patients with primary squamous cell carcinoma (SCC) of the lips or oral cavity is reported. The mean age was 63 years. The mean onset of oral cancer in women was 7 years later than in men. Patients under the age of 40 years were mainly males. The male-to-female ratio ranged from 8.3 for the lower lip to 0.9 for the upper alveolar ridge with an overall ratio of 1.8. In the case of multiple oral SCCs the tongue was the most frequently affected site. No significant association was found between the age or gender of patients and the size of the tumour. However, a significant association was observed between the site and size of the tumour. Lesions of the lower lip had a significantly smaller size than tumours of other sites. Furthermore, a linear trend could be observed between the size of the tumour and the clinical stage of the neck.
  Journal of Cranio-Maxillofacial Surgery 07/1993; 21(4):149-52. · 1.64 Impact Factor
• Article: Delay in diagnosis of oral squamous cell carcinoma; a report from The Netherlands.

  A Jovanovic, P J Kostense, E A Schulten, G B Snow, I van der Waal
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  ABSTRACT: The referral pattern, patients' and doctors' delay of a limited number of 50 patients suffering from oral squamous cell carcinoma have been investigated. The majority of the patients consulted the family doctor as the first source of help. The mean patients' and doctors' delay was 103 and 22 days, respectively the median being 35 and 11 days, respectively. The gender, dental status, site and tumour size did not show a significant correlation with the delay. Measures directed to the early detection of oral cancer should place special emphasis on the patients' delay.
  European Journal of Cancer Part B Oral Oncology 08/1992; 28B(1):37-8.
• Article: Referral pattern of patients with oral mucosal lesions in The Netherlands.

  A Jovanovic, E A Schulten, I van der Waal
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  ABSTRACT: The referral pattern of 140 Dutch patients with oral mucosal lesions, who had been referred to a Department of Oral & Maxillofacial Surgery and Oral Pathology, shows that patients with oral mucosal lesions consult the dentist as often as the family doctor as the first source of help or information. Furthermore, family doctors were much more used to refer patients with oral mucosal disease to medical specialists rather than to the dentist or the oral and maxillofacial surgeon.
  Community Dentistry And Oral Epidemiology 05/1992; 20(2):94-6. · 1.89 Impact Factor
• Article: [Prevalence study of oral mucosal lesions in 300 patients].

  E A Schulten, A Jovanovic, I van der Waal
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  ABSTRACT: Intraoral examination was performed in 300 consecutive patients, who attended the Department of Oral and Maxillofacial Surgery of the Free University Hospital, Amsterdam. In 89% of the patients one or more oral mucosal lesions were observed. Fordyce's spots, coated tongue, leukoedema, melanin pigmentation, frictional keratosis, and morsicatio buccarum were the most frequent occurring lesions.
  Nederlands tijdschrift voor tandheelkunde 12/1989; 96(11):538-9.