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Clinical and molecular hepatology. 03/2013; 19(1):92-96.
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ABSTRACT: Bleeding jejunal varices are rare and could be life threatening. They are usually found in the presence of portal hypertension and prior history of gastrointestinal surgery. They can be effectively managed by radiological interventions such as transjugular intrahepatic portosystemic shunt or transhepatic embolization of varices. However, in patients with portal vein obstruction, an alternative access is necessary. We report a case of bleeding jejunal varices associated with postoperative adhesion in a patient with portal vein thrombosis which was successfully managed by percutaneous transsplenic embolization.
Abdominal Imaging 04/2012; · 1.73 Impact Factor
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ABSTRACT: The purposes of this study were to assess retrospectively whether the waveform change during respiration on hepatic vein Doppler sonography is a parameter of severe portal hypertension as estimated by the hepatic venous pressure gradient (HVPG) and to compare with a hepatic vein damping index (DI) at expiration.
Spectral Doppler sonography of the hepatic vein was performed on 22 consecutive patients who underwent HVPG measurement for portal hypertension with liver cirrhosis. From the maximum and minimum velocities of systolic hepatofugal venous flow on Doppler sonography, 3 parameters were derived: damping index at expiration (DI(exp)), damping index ratio (DI(ratio)), and damping index difference (ΔDI) between inspiration and expiration. Considering an HVPG level of 12 mm Hg or higher as the threshold level for high-grade portal hypertension, we assessed the diagnostic capability of these Doppler sonographic parameters to discriminate using receiver operating characteristic curve analysis.
Area under the curve values for the DI(ratio) and ΔDI (0.875 and 0.889, P = .807 and .682, respectively) were slightly higher than the area for the DI(exp) (0.861; respectively). When the DI(exp) was greater than 0.56, the sensitivity and specificity for high-grade portal hypertension were 66.7% and 100.0%, respectively. In the case of the DI(ratio), the sensitivity and specificity were 77.8%, and 100.0% at greater than 0.69. The corresponding sensitivity and specificity at a value of 0.25 or less for the ΔDI were 83.3% and 100.0%.
The ratio and difference of the DI of the hepatic vein waveform are helpful parameters in assessing the severity of portal hypertension as well as using the existing DI on its own.
Journal of ultrasound in medicine: official journal of the American Institute of Ultrasound in Medicine 04/2011; 30(4):455-62. · 1.25 Impact Factor
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Seung Soo Lee,
Seong Ho Park,
Hye Jin Kim,
So Yeon Kim, Min-Yeong Kim,
Dae Yoon Kim,
Dong Jin Suh,
Kang Mo Kim,
Mi Hyun Bae,
Joo Yeon Lee,
Sung-Gyu Lee,
Eun Sil Yu
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ABSTRACT: Despite increasing use of various imaging examinations for non-invasive assessment of hepatic steatosis (HS), their relative accuracy is unknown. The objective of this study is to prospectively compare the accuracy of computed tomography (CT), dual gradient echo magnetic resonance imaging (DGE-MRI), proton magnetic resonance spectroscopy ((1)H-MRS), and ultrasonography (US) for the diagnosis and quantitative estimation of HS.
A total of 161 consecutive potential living liver donors underwent US (performed by two independent radiologists, US1 and US2), CT, DGE-MRI, (1)H-MRS, and liver biopsy on the same day. Using the histologic degree of HS as the reference standard, we compared the diagnostic performance of US1, US2, CT, DGE-MRI, and (1)H-MRS for diagnosing HS >or= 5% and HS >or= 30% and compared the accuracy of CT, DGE-MRI, and (1)H-MRS in the quantitative estimation of HS.
DGE-MRI and (1)H-MRS significantly outperformed CT and US for the diagnosis of HS5%. DGE-MRI showed a tendency of higher accuracy than the other examinations for diagnosing HS >or= 30%. The cross-validated sensitivity and specificity of DGE-MRI at the optimal cut-off were 76.7% and 87.1%, respectively, for diagnosing HS >or= 5% and 90.9% and 94%, respectively, for diagnosing HS >or= 30%. The cross-validated Bland-Altman 95% limits of agreement between the estimated degree of HS on imaging examinations and the histologic degree of HS, were the narrowest with DGE-MRI, yielding -12.7% to 12.7%.
Among CT, DGE-MRI, (1)H-MRS, and US, DGE-MRI is the most accurate method for the diagnosis and quantitative estimation of HS. Therefore, DGE-MRI may be the preferred imaging examination for the non-invasive assessment of HS.
Journal of Hepatology 02/2010; 52(4):579-85. · 9.26 Impact Factor
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ABSTRACT: Institutional review board approval and informed consent were obtained. This study was conducted to evaluate a newly developed technique for discriminative color coding of tagged stool during three-dimensional (3D) endoluminal fly-through computed tomographic (CT) colonography and to determine its effect on reading efficiency. Thirty patients, including three dropouts, were prepared with moderate cathartic preparation (20 mg bisacodyl, three doses of 200 mL of 5% wt/vol barium sulfate). Images were reviewed by two independent readers with and without color coding. Reader preference, interpretation time, and diagnostic performance were evaluated. Both reviewers preferred color coding. With color coding, interpretation time was shortened by 3 minutes (reader 1, P = .002) and 2.5 minutes (reader 2, P = .009); sensitivity for 6-mm-diameter or larger lesions remained constant at 96% (24 of 25; 95% confidence interval: 78.9%, <100%; P = >.99). This technique facilitates primary 3D interpretation of images obtained with moderate cathartic preparation.
Radiology 09/2008; 248(3):1018-27. · 5.73 Impact Factor
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Soo Mee Lim,
Eun Jin Chae, Min Yeong Kim,
Jae Kyun Kim,
Sang Joon Kim,
Choong Gon Choi,
Jae Sung Ahn,
Young-Shin Ra,
Jong-Uk Kim,
Kyung Don Hahm,
Hae Wook Pyun,
Dae Chul Suh
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ABSTRACT: Branch occlusion of the anterior cerebral artery (ACA) is regarded as a part of Moyamoya disease. The purpose of this study is to define the ACA steal phenomenon (SP) in Moyamoya disease and to evaluate temoporal changes according to the disease progression. From 139 Moyamoya patients we defined ACASP as narrowing of the ipsilateral A1-2 junction while preserving the anterior communicating artery and supplying the contralateral ACA cortical branches with the development of leptomeningeal collaterals by the ipsilateral middle cerebral artery into the hypoperfused ipsilateral ACA territory. Direction of the steal related to the stage in both hemispheres by Suzuki classification was statistically analyzed using the binomial test based on binomial distribution. Follow-ups of ACASP were evaluated in five patients. We identified ACASP in 13 (9%) patients (male:female=7:6, mean age 18 years, range: 2-58 years) of the 139 study patients. The presenting pattern was ischemic in 12 and hemorrhagic in one. The direction of SP occurred from the hemisphere in the lower to the higher stage of Suzuki classification (two-tail P value=0.0002). After revascularization surgery, ACASP disappeared or diminished. ACASP may occur in bilaterally different stages of Moyamoya disease as a transient self-adaptive process. It regresses after revascularization surgery.
European Radiology 02/2007; 17(1):61-6. · 3.22 Impact Factor
