Mehrad M Jaberi

McGill University, Montréal, Quebec, Canada

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Publications (3)7.3 Total impact

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    ABSTRACT: Electromagnetic fields have been proposed to enhance healing of cartilage defects by stimulation of chondrocyte proliferation, proteoglycan synthesis as well as decreasing pain and improving motion in osteoarthritic patients. However, the effects of a moderate-intensity static magnetic field on cartilage repair have not been investigated. This study tries to determine the effects of a moderate-intensity permanent magnetic field of 40 mT on cartilage repair. Defects of 3 mm in diameter and 6 mm in depth were made on the weight bearing surface of the right medial femoral condyle of 30 rabbits. The animals were divided randomly into three equal groups (magnet, sham and control). In the magnet group, cylindrical permanent magnets were implanted subcutaneously medial to the medial femoral condyle, while in the sham group the cylindrical ceramic were not magnetized, and nothing was implanted in controls. After 12 weeks of observation, Mankin's microscopic scoring was done on all specimens, and irregularity of surface characteristics, cell colonization, hypocellularity, cartilage matrix formation, and presence of empty lacunae were investigated. Each of these characteristics showed significant differences in magnet group relative to control and sham groups (p <0.05). Mankin's score was 1.6 ± 0.6 in magnet group, 7.2 ± 1.6 in sham group and 7.7 ± 1 in control group (p <0.001). CONLUSIONS: In this animal study, microscopic Mankin's scoring depicted histological improvement in cartilage of magnet group.
    Archives of medical research 05/2011; 42(4):268-73. DOI:10.1016/j.arcmed.2011.06.004 · 2.65 Impact Factor
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    ABSTRACT: Among several graft fixation options in arthroscopic ACL reconstruction for hamstring tendons, transcondylar fixation has been suggested to offer mechanical advantages compared to other femoral fixation systems. Blind nature of the procedure may result in several complications including iliotibial band irritation syndrome, breakage of the bio absorbable cross-pin, stress fracture of the femoral cortex, and more commonly intraoperative wire loop twisting, resulting in fixation failure, wire breakage or graft laceration. We used "wireless" transfixation technique to avoid complications associated with wire loop.
    Knee Surgery Sports Traumatology Arthroscopy 02/2010; 18(11):1508-10. DOI:10.1007/s00167-010-1079-3 · 3.05 Impact Factor
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    ABSTRACT: This study presents a modification of tibial inlay technique in posterior cruciate ligament (PCL) reconstruction and evaluates the structural properties of tibial side fixation of the graft, comparing tibial inlay technique and a new modification, that is interference screw fixation of tibial side of the graft in suggested supine position which is more applicable, with less potential intraoperative neurovascular complications. Forty fresh calf knees that were prepared from 20 healthy 3 years old calves which were between 200 and 220 kg were the subject of this study. The tibias were separately used simulating tibial side PCL reconstruction with tibial tuberosity-patellar tendon-patellar bone graft. Tibial side of the graft was fixed using two cancellous screws in 20 tibiae and with interference screw in obliquely oriented canal in another 20 tibiae. Load-to-failure test was carried out on ten samples from each group. The remaining samples were used for cycling loading. Mann-Whitney U test was used to compare structural properties of each group. No significant differences were observed between two methods at load-to-failure test; but mean elongation at 1,000 cycles of new modification was significantly lower than tibial inlay technique.
    Archives of Orthopaedic and Trauma Surgery 10/2008; 130(9):1065-9. DOI:10.1007/s00402-008-0734-3 · 1.60 Impact Factor