Publications (3)2.83 Total impact
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Article: Value of diffusion-weighted MRI in the differentiation of benign and malign breast lesions
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ABSTRACT: INTRODUCTION: Our purpose was to determine whether diffusion-weighted MR imaging (DWI) could be used in differentiation of benign and malign breast lesions. MATERIALS AND METHODS: 41 women patients were included in the study. 45 lesions were diagnosed by biopsy; 25 (55.5%) of these lesions were malignant and 20 (44.5%) were benign. The apparent diffusion coefficient (ADC) values of these lesions were prospectively compared with their histopathological results. RESULTS: Differentiation of the malignant and benign masses revealed that the threshold value of the ADC was 1.0×10–3 mm2/s, its sensitivity was demonstrated as 95%, specificity as 100%, positive predictive as 100%, negative predictive as 94% and accuracy rate as 97%. CONCLUSIONS: DWI improves diagnostic accuracy of the conventional breast MRI. ADC measurements may be useful for differentiation of the malign and benign masses. EINLEITUNG: Ziel unserer Studie war es, zu prüfen, ob eine diffusionsgewichtete MR Bildgebung (DWI) in der Differenzierung von benignen und malignen Läsionen der Brust nützlich ist. MATERIAL UND METHODEN: Es wurden 41 Frauen in die Studie eingeschlossen. Bei 45 Läsionen wurde die Diagnose bioptisch gestellt, wobei 25 (55,5 %) malign und 20 (44,5 %) gutartig waren. Der apparente Diffusions Koeffizient (ADC) dieser Läsionen wurde prospektiv mit dem histopathologischem Ergebnis verglichen. ERGEBNISSE: Als Schwellenwert zur Erkennung maligner Läsionen wurde ein ADC von 1,0×10–3 mm2/s erhoben. Die Sensitivität dieses Wertes lag bei 95 %, die Spezifität bei 100%. Der positive Voraussagewert bei 100 %, der negative bei 94 %, die Treffsicherheit -Rate bei 97 %. SCHLUSSFOLGERUNGEN: Die DWI verbessert die diagnostische Treffsicherheit der konventionelle MRI der Brust. ADC Messungen können bei der Differenzierung von malignen und benignen Läsionen der Brust nützlich sein. KeywordsBreast cancer–Breast mass–Magnetic resonance imaging–Diffusion-weighted imaging–Apparent diffusion coefficientWiener klinische Wochenschrift 04/2012; 123(21):655-661. · 0.81 Impact Factor -
Article: Value of diffusion-weighted MRI in the differentiation of benign and malign breast lesions.
[show abstract] [hide abstract]
ABSTRACT: Our purpose was to determine whether diffusion-weighted MR imaging (DWI) could be used in differentiation of benign and malign breast lesions. 41 women patients were included in the study. 45 lesions were diagnosed by biopsy; 25 (55.5%) of these lesions were malignant and 20 (44.5%) were benign. The apparent diffusion coefficient (ADC) values of these lesions were prospectively compared with their histopathological results. Differentiation of the malignant and benign masses revealed that the threshold value of the ADC was 1.0 x 10(-3) mm(2)/s, its sensitivity was demonstrated as 95%, specificity as 100%, positive predictive as 100%, negative predictive as 94% and accuracy rate as 97%. DWI improves diagnostic accuracy of the conventional breast MRI. ADC measurements may be useful for differentiation of the malign and benign masses.Wiener klinische Wochenschrift 09/2011; 123(21-22):655-61. · 0.81 Impact Factor -
Article: Split-cord malformation and accompanying anomalies.
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ABSTRACT: To present the magnetic resonance imaging (MRI) appearances of spinal split-cord malformation (SCM) and to investigate the various types of congenital spinal disorders associated with SCM. MR examinations of 23 patients with SCM were carried out in our hospital between June 2002 and May 2007 and retrospectively analysed. Nineteen (82.6%) patients were diagnosed as type I SCM, while four (17.4%) were diagnosed as type II SCM. The most commonly involved site of SCM was the dorsolumbar area (47.8%) while cervical involvement was the least common (4.3%). No accompanying congenital spinal disorders were detected in four patients (17.4%). In 19 patients (82.6%), congenital spinal disorders accompanying SCM were detected, the most common of which was a low-lying cord, found in 14 patients (60.9%). Other anomalies included hydromyelia in seven patients (30.4%), lipoma in six (26%), meningomyelocele in four (17.4%), thick filum in three (13%) and dermoid cyst in three (13%). In preoperative planning for SCM, its characteristics and those of the accompanying anomalies should be determined. MRI is a valuable tool for making such determinations.Journal of Neuroradiology 08/2008; 35(3):150-6. · 1.21 Impact Factor
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Institutions
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2008–2012
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Haydarpasa Numune Research and Teaching Hospital
İstanbul, Istanbul, Turkey
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