José Carlos Rivero Vera

Publications (1)1.64 Total impact

• Article: Hypoglycemic coma secondary to big insulin-like growth factor II secretion by a giant phyllodes tumor of the breast.

  David Aguiar Bujanda, José Carlos Rivero Vera, Miguel Angel Cabrera Suárez, José Aguiar Morales, Rémy Christol, Uriel Bohn Sarmiento, Casimira Domínguez Cabrera, Yves Le Bouc
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  ABSTRACT: Nonislet cell tumor hypoglycemia (NICTH) is uncommon, and has been related to the production of insulin-like growth factor II or its high-molecular-weight precursor (big IGF-II) by the tumor. Cases of NICTH have been related to different tumors, mainly sarcomas. However, only three cases secondary to a phyllodes tumor of the breast (PTB) have been previously reported. We present the clinical course of a woman with a giant PTB, who developed an irreversible hypoglycemic coma secondary to big IGF-II production by the tumor. A brief review of the literature and possible mechanisms of this infrequent condition are also commented.
  The Breast Journal 13(2):189-91. · 1.64 Impact Factor