[Show abstract][Hide abstract] ABSTRACT: Background: Demodex species are ectoparasites living in the hair follicles and sebaceous glands in human. Only two species, Demodex folliculorum and D. brevis were identified in human. While the D. folliculorum is settling in infundibular part of the hair follicles mostly, D. brevis settles into the sebaceous glands and ducts, which are deeper. These parasites live preferentially in hair follicles on the face and in the sebaceous glands, although they have also been reported to reside in seborrheic parts of the human body. The Demodex species have the highest rate on the face which has thesignificant number of sebaceous glands and sebum production in the skin. However, the rate of infestation increases with age in healthy skin. Objectives: The aim of this study was to determine the prevalence of Demodex species in healthy women and the relationship between the incidence of Demodex and metabolic syndrome (MetS). Patients and Methods: This study consisted of 151,498 women aged ≥ 20 years who reside in the central district of Malatya province, Turkey. In 5% confidence interval of sample size, while the design effect was 1.5 it was calculated as 552 individuals and while the design effect was 2 it was calculated as 736 individuals. The World Health Organization 30 cluster sampling method was used to select the samples. Women aged ≥ 20 years who were not pregnant or lactating were included in the study. From a total of 669 subjects included in this study, 90.89% of the largest sample was accessed. Results: Parasites were detected in 263 (39.3%) of 669 subjects and 3 of them were D. brevis. In chi-square analysis, nosignificant relationship was found between the incidence of the parasite, age, education level, occupation, marital status, family type, and MetS. However, a significant relationship was found between the diastolic pressure and those who fed with fatty foods and the incidence of parasite’s occurrence. Conclusions: According to the results of this study, MetS has no effect on the frequency of occurrence of the parasite; however, weight, fatty foods, and high diastolic pressure are effective in the frequency of occurrence of the parasite. The effects of these factors on the incidence of parasites should be supported by further study designs.
[Show abstract][Hide abstract] ABSTRACT: Objective: The aim of study was to evaluate depression and impulsivity in obese people with binge eating
Method: The study included 149 obese subjects who were compared to 151 non-obese healthy controls.
They were assessed with the Structured Clinical Interview (SCID-I), Eating Attitudes Test (EAT), Beck
Depression Inventory (BDI), and Barratt Impulsiveness Scale-11 (BIS-11).
Results: The prevalence of BED was 47.6% in the obese subjects. Obesity with BED was more common in
females. Depressive disorder was detected in 41.2% of the obese subjects. There was no significant difference
between BED (+) and BED (-) groups with respect to depressive disorder (p>0.05). The cognitive impulsivity
and non-planning activity scores of the depressive group were significantly higher than for the subjects
without depression (p<0.05). The cognitive impulsivity scores of depressive obese subjects were significantly
higher than for obese subjects without depression (p<0.05).
Conclusion: Obesity appears to be associated with depression rather than impulsivity. Impulsivity was found
in obese people with binge-eating specifically. This study suggests that depression and/or binge eating may
be mediating factors for the outcome of obesity.
[Show abstract][Hide abstract] ABSTRACT: Background: Cyclospora species are rare among other Coccidia parasites and can cause recurrent gastroenteritis. Cyclospora spp. can infect reptiles, insects, rodents, and mammals. Objectives: The present study aimed to determine the epidemiology of Cyclospora spp. in Malatya province and its neighboring provinces. Patients and Methods: Totally, 2281 stool samples taken from patients with digestive system complaints who referred to the polyclinics afliated with Inonu University, Faculty of Medicine in Malatya Province and its neighboring provinces, in 2006, and whose stool specimens were submitted to the parasitology department were examined. A questionnaire was developed to determine the epidemiology of Cyclospora spp. in the patients as the dependent variable of the study. All the participants signed an informed written consent. The samples were coated with Entellan™ after staining via acid-fast staining and were examined on an immersion microscope objective. The data are presented as mean, standard deviation, or number/percentage. The chi-square test was used for the statistical analyses. Statistically, a P value < 0.05 was accepted as meaningful. Results: The stool samples were examined via direct microscopic examination and acid-fast staining. Positivity was determined in 129 (5.7%) cases. In the overall assessment of the patients with respect to general body itching, rectal itching, allergy, immunosuppression plus cancer, shortness of breath, ulcerative colitis, diarrhea, abdominal pain, salivation, constipation, nausea, vomiting, growth retardation, and anemia, there was no significant relationship. However, in the statistical evaluations among the positive cases, the diference was found to be significant. Conclusions: The study was conducted in Malatya Province, but patients from the neighboring provinces were also included in the evaluation during the study. Of all the positive cases, 5.6% were those from Malatya Province and its surrounding areas. Additionally, Cyclospora spp. were observed among the patients referring to the polyclinics with digestive system complaints in 8.1% of those from the Adiyaman province and in 6.9% of those from the Kahramanmaraş region. The incidence of Cyclospora cayetanensis may be higher in these regions if an epidemiological study is performed. Consequently, we suggest that Cyclospora spp. be investigated in digestive system disorders, especially in immunosuppressed patients.
[Show abstract][Hide abstract] ABSTRACT: Hemodynamic status, cardiac enzymes, and imaging-based risk stratification are frequently used to evaluate a pulmonary embolism (PE). This study investigated the prognostic role of a simplified Pulmonary Embolism Severity Index (sPESI) score and the European Society of Cardiology (ESC) model. Methods : The study included 50 patients from the emergency and pulmonology department of one medical center between October 2005 and June 2006. The ability of the sPESI and ESC model to predict short-term (in-hospital) and long-term (6-month and 6-year) overall mortality was assessed, in addition to the accurancy of the sPESI and ESC model in predicting short-term adverse events, such as cardiopulmonary resuscitation, or major bleeding. Results : Of the 50 patients, the in-hospital and 6-year mortality rates were 14% and 46%, respectively. Fifteen (30%) of these experienced adverse events during hospitalization. Importantly, patients classified as low-risk according to the sPESI had no short-term adverse events as opposed to 4.8 % in the ESC low-risk group. They also had no in-hospital, 6-month, or 6-year mortality compared to 4.8%, %14.3, and %23.8, respectively, in the ESC low-risk group.
The sPESI predicted short-term and long-term survival. The exclusion of short-term adverse events does not appear to require imaging and laboratory testing.
Pakistan Journal of Medical Sciences Online 11/2014; 30(6):1259-64. DOI:10.12669/pjms.306.5737 · 0.23 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: Objective:
Demodex folliculorum and Demodex brevis can cause different skin and eye symptoms. There are indications showing that the prevalence of these parasites is higher in public places. In this direction, the study was aimed to determine the prevalence of demodex in university students, inhabiting in dormitories.
The study consisted of 300 men and women, college students who were staying in the dormitories in the city of Ordu. Random sampling method was used in the sample selection. Each participating student had to sign a patient's consent form, before samples were taken using standard superficial skin biopsies from the faces of the patients. The samples were embedded in Entellan mounting solution and examined under the light microscope.
Samples were taken from 300 college students (170 males and 130 females) aged between 18-30 years, and in 110 (37%) of them, demodex mites were found. No significant differences were found between gender, age, type of skin or skin care, and Demodex incidence.
Demodex mites are very prevalent in college students studying in Ordu.
[Show abstract][Hide abstract] ABSTRACT: There are limited data regarding the pattern of Helicobacter pylori (Hp) antibiotic resistance and virulence factors in children. Evaluation of prevalence of drug resistance and virulence-factor genotype in children with Hp gastritis and to investigate whether there is any relation between drug resistance and genotype were our aims in this study.
Ninety-eight children with polymerase chain reaction-positive Hp gastritis were included. Antimicrobial susceptibility was tested by disc diffusion method and polymerase chain reaction assays were used for the determination of virulence factors.
The resistance rates to clarithromycin, metronidazole, and amoxicillin were 23.5%, 11.7%, and 3.9%, respectively. All strains carried vacA genotype, and 51%, 70.4%, 49%, 34.7%, and 25.5% were cagA-, cagE-, babA2-, iceA1-, and iceA2-positive, respectively. Of those 98 specimens, 81.6%, 19.4%, 38.8%, and 63.3% carried vacAs1, vacAs2, vacAm1, and vacAm2, respectively. Dominant vacA type was s1am2 (32.7%), followed by s1am1 (14.3%) and s2m2 (12.2%). Significant rates of clarithromycin resistance were observed in cagE-, iceA1-, babA2-, and vacAs1c-positive groups. In those with metronidazole resistance, vacAs1 and vacAs1c were more common (P < 0.05).
The cagE-positive and vacA s1a/m2 genotypes, which are correlated with increased antibiotic resistance, were predominant in our population. In countries where Hp infection is prevalent, studies focusing on virulence factors and antibiotic susceptibility may provide anticipation of the prognosis and may be helpful to reduce morbidity and mortality.
Journal of pediatric gastroenterology and nutrition 05/2014; 58(5):608-12. DOI:10.1097/MPG.0000000000000273 · 2.63 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: As there are limited data regarding the correlation between virulence factors and clinical, endoscopic, and histological findings in children with Helicobacter pylori gastritis, we aimed to evaluate that probable relationship in pediatric cases.
One hundred and fifty-nine children with chronic abdominal pain or dyspepsia were included in this study. Upper gastrointestinal endoscopy was performed and multiple biopsy samples were taken from the esophagus, the antrum, and the duodenum. PCR was used for the determination of virulence factors.
According to PCR analysis, 98 (61.6%) children were positive for H. pylori. Using histopathological examination and culture, H. pylori was detected in 65 (40.9%) and 51 (32.1%) children, respectively. Peptic ulcer prevalence and histopathological features were not different among cagA, cagE, or iceA1 positive and negative groups (P>0.05). Peptic ulcer prevalence and histopathological findings were more common in iceA2-positive patients (P<0.05). Antral nodularity was more common in cagA-positive patients (P<0.05). Endoscopic and histological features were not different among patients with or without m1 or m2 strains (P>0.05). S1b positivity was associated with a higher esophagitis rate (P<0.05).
Among virulence factors, iceA2 was associated with peptic ulcer and milder histopathological findings, and vacAs1 was associated with milder histopathological findings.
European journal of gastroenterology & hepatology 04/2014; 26(6). DOI:10.1097/MEG.0000000000000095 · 2.25 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: Chronic obstructive pulmonary disease (COPD) is a respiratory disorder, and is characterized by persistent airflow obstruction. These patients are exposed to severe physical limitations and substantial psychosocial trouble. The aims of this study were to determine the temperament and character profiles of personality in patients with COPD and to compare the results with those of healthy controls.
Thirty-nine male COPD patients and 67 age- and gender-matched healthy controls completed the self-administered 240-item temperament and character inventory (TCI) and 14-item hospital anxiety and depression scale. The relationships between temperament and character personality profiles and clinical factors such as severity of COPD, anxiety, and depression were evaluated.
COPD patients had significantly higher mean scores of Harm avoidance and lower mean score of Self-directedness than those of healthy controls. In the COPD patients, the anxiety score was significantly higher (P=0.03) and the depression score was found to be insignificantly higher than that of control group. The TCI profiles were not correlated with the severity of COPD. In COPD patients, Self-directedness and Cooperativeness traits of TCI character negatively correlated with anxiety, but any of traits did not correlate with depression.
The present study defined the Harm avoidance score was higher and Self-directedness was lower in COPD patients and the COPD severity did not correlate with any of the personality trait. We suggest that during evaluation of COPD patients for treatment, personality trait should also be considered in clinical practice.
[Show abstract][Hide abstract] ABSTRACT: Background: Acne is the most common skin disease, affecting nearly 85% of the population as well as their lives. Acne can severely affect social and psychological functioning. Patients with acne may have anxiety, depression, decreased self-esteem, interpersonal difficulties, unemployment, social withdrawal, and even suicidal intent. Aims: The aim of this study was to evaluate the temperament and character inventory (TCI) of patients with acne and to compare the results with those of healthy controls. Study Design: Case-control study Methods: The study population consisted of 47 patients with acne, and 40 healthy control subjects. All participants were instructed to complete a self-administered 240-item TCI and the Hospital Anxiety and Depression Scale. Results: In this study, the scores for the temperament properties Worry and pessimism (HA1) and Dependence (RD4) and the character properties Social acceptance (C1) and Integrated conscience (C5) were found to be higher in acne patients than in healthy controls (p<0.05). Compared to the controls, depression and anxiety scores were found to be markedly higher in the patients with acne. Acne type correlated positively with the Disorderliness (NS4) subscale of Novelty seeking (NS) and anxiety. Additionally, acne type correlated negatively with the Attachment (RD3) subscale of Reward Dependence (RD), with the Transpersonal identification (ST2) and Spiritual acceptance (ST3) subscales of Self-Trancendence (ST), and with the Compassion (C4) subscale of Cooperativeness (C). Conclusion: Studies in this area may lead to the development of specific and focused interventions for TCI in patients with acne vulgaris. We suggest that the evaluation and treatment of acne should also include psychosomatic approaches in clinical practice.
Balkan Journal of Medical Genetics 06/2013; 30(2):161-6. DOI:10.5152/balkanmedj.2012.101 · 0.50 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: Objective: The aim of this study was to evaluate the differences among dimensions of temperament and character within type 2 diabetes patients. Methods: Temperament and character inventory, Montgomery-Asberg Depression Rating Scale, Hamilton Anxiety Rating Scale were administered to type 2 diabetes patients and control groups. Results: Anxiety and depression scores were significantly higher in patients with type 2 diabetes (p=0.0001 and p=0.009, respectively). According to inventory, the scores of harm avoidance-fatigability, self directedness-resourcefulness, and cooperativeness-helpfulness of patients were significantly different from controls (p=0.001, p=0.004 and p=0.040, respectively). Conclusions: Our research findings indicate that the patients with type 2 diabetes differ from the control group members in terms of higher levels of anxiety and depression as well as the temperament and character traits of fatigability; resourcefulness and helpfulness.
[Show abstract][Hide abstract] ABSTRACT: Introduction:
The aim of our study is; to assess the approach of smokers to tobacco law, examine changes in their smoking related behaviors after the new law and determine the factors associated with these changes.
Materials and methods:
Data collected by questionnaire including 30 question. We applied the questionnaire to 1509 current smokers, and ex-smokers who quitted smoking after the law. SPSS packet programme was used for analyses.
Participants consisted of 419 (28.0%) female, 1090 (72.0%) male with an average age of 33.6 ± 10.5 years. Although 80% of them knew that passive smoking is harmful to non-smokers, rate of smoking at home and in the car were very high. 869 (58.0%) of participants supported the law. 87 (5.8%) smokers quitted smoking after the law, 316 (20.9%) reduced. While health problems (37.3%) were the most frequent reason for quitting, restriction of smoking area had the most effect to reduce (54.2%).
We satisfied that; the new tobacco law encouraged smokers to quit smoking. In addition, the majority of smokers supported the law.
Tuberkuloz ve toraks 12/2012; 60(4):350-4. DOI:10.5578/tt.3549
[Show abstract][Hide abstract] ABSTRACT: Objective: Laparoscopic surgery has become increasingly popular in urology over the last decade. This survey was performed to evaluate the current practice patterns in laparoscopy among urologists in Turkey. Material and methods: A detailed questionnaire about urologic laparoscopic practice patterns was distributed to 1242 urologists who were working in Turkey. The questions pertained to age, practice demographics, and the amount and variety of laparoscopy performed. Results: Nearly half of the respondents (48.3%) already performed laparoscopy. Of the urologists in academic settings, including university hospitals and education and research hospitals, 69.6% and 59.4% performed laparoscopy, respectively. In state hospitals, the percentage of those who performed laparoscopy was lower (26.9%). The most important reasons mentioned for performing laparoscopy were shorter hospital stay, patient requests and greater flexibility of possible surgical techniques. The main laparoscopic procedures performed were nephrectomy (benign indication), 91%; renal cyst decortications, 90%; nephrectomy (malign indication), 65%; laparoscopic stone surgery, 47% and pyeloplasty, 38%. A large percentage (77.2%) of respondents intended to attend continuing education and to perform laparoscopy in the future. Conclusions: Our results show that laparoscopic practice steadily increases in frequency and that urologists are willing to substitute open surgery for laparoscopic surgery. The performance of laparoscopic surgery has become a goal for most urologists in Turkey to achieve in the near future.
Turk Uroloji Dergisi 11/2012; 38(4):201-204. DOI:10.5152/tud.2012.042
[Show abstract][Hide abstract] ABSTRACT: Trichodynia refers to pain, discomfort, and/or paresthesia of the scalp. Trichodynia may be associated with anxiety.
To assess serum vitamin B12, folate, thyroid stimulating hormone (TSH), ferritin, and zinc levels, and to investigate anxiety in telogen alopecia patients with trichodynia.
The study included 31 telogen alopecia patients who complained of trichodynia and 30 telogen alopecia patients without trichodynia. Their serum vitamin B12, folate, TSH, ferritin, and zinc levels were assessed and their anxiety levels were scored using the Beck Anxiety Inventory (BAI) and the State-Trait Anxiety Inventory (STAI).
No significant difference was found in the serum levels of vitamin B12, folate, TSH, ferritin, and zinc in the patient and control groups. The anxiety scores in both groups were similar.
Our data provide no evidence for the association of serum vitamin B12, folate, TSH, ferritin, and zinc levels or anxiety scores with trichodynia.
International Journal of Trichology 10/2012; 4(4):251-4. DOI:10.4103/0974-7753.111208
[Show abstract][Hide abstract] ABSTRACT: The purpose of this study was to investigate the ovarian protective effects of resveratrol in rats exposed to total body irradiation.
Thirty female rats were randomized into four groups: (1) control group (n = 7); (2) low-dose (10 mg/kg) resveratrol group (n = 8); (3) high-dose (100 mg/kg) resveratrol group (n =7); and (4) sham irradiation group (n = 8). The drugs were administered intraperitoneally as single doses, and the rats were exposed to total body radiation 24 h after the treatment. The animals were sacrificed the following day, and their ovaries were excised for histopathological and biochemical analysis.
The ovarian follicle counts were calculated, and irradiation-dependent ovarian damage and tissue levels of antioxidant enzymes were evaluated.
Group 2 and Group 3 showed significantly higher numbers of total follicle counts compared with Group 1 (P < 0.01). The low-dose resveratrol treatment was associated with significantly higher numbers of primary follicles than the high-dose group. The tissue activities of glutathione peroxidase (GsH-Px) and catalase (CAT) were significantly elevated in the resveratrol-treated animals. Evaluation of ovarian histology revealed no remarkable changes in fibrosis and leucocyte infiltration among the resveratrol-treated and control rats; however, vascularity was significantly reduced in the high-dose group (P = 0.014).
Resveratrol attenuated irradiation-dependent ovarian damage, suggesting that this natural antioxidant is effective in reducing the follicle loss induced by ionizing radiation.
Journal of pediatric and adolescent gynecology 08/2012; 25(4):262-6. DOI:10.1016/j.jpag.2012.04.001 · 1.68 Impact Factor
[Show abstract][Hide abstract] ABSTRACT: In this study, we aimed to determine the different sociodemographic variables of polygamous and monogamous wives, and the relationship between depression and polygamous marriage. Seventy-nine polygamous wives and 73 monogamous wives from Kahramanmaras, located in southern Turkey, were interviewed. After reviewing the data, we suggest that there is a statistically significant difference between polygamous wives and monogamous wives in terms of Beck Depression Inventory (BDI) scores. The results highlighted many implications for clinical practice and for future research. Additional research needs to be conducted in order to investigate the effects of polygamy on women's mental health.
Health Care For Women International 08/2012; 34(11). DOI:10.1080/07399332.2012.692414 · 0.63 Impact Factor