Publications (2)0 Total impact
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ABSTRACT: To retrospectively analyze oral lichen planus (OLP) patients and to summarize the clinical characteristic of OLP in Chinese patients. A total of 724 patients with histologically and clinically confirmed OLP were collected from department of oral mucosa in School of Stomatology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University between 1978 and 2006. The OLP patients were followed up from 1 month to 259 months (mean 21 months). Of the 724 patients, 68.23% were women and 31.77% were men. The buccal mucosa was the most common site of involvement in each form, followed by the dorsal tongue, ventral tongue, lip, gingiva, palate and the floor of mouth. The reticular form of the disease was the predominant type in 53.82% of patients at initial presentation. About 48.76% of the patients had multiple oral sites of involvement. Fifteen OLP lesions developed into carcinoma, the malignant transformation rate was 2.07%. Because OLP has potential of malignant change, a long time and periodical follow-up is of great importance for detection of malignant lesions.Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 12/2007; 42(11):669-71.
Article: [The application of 18F-fluorodeoxyglucose positron emission tomography in the diagnosis and staging of lung cancer].[show abstract] [hide abstract]
ABSTRACT: To study the clinical value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in the diagnosis and staging of lung cancer. Ninety-four patients with lung nodular changes were examined by CT, 18F-FDG PET and pathology, cytology. 18F-FDG PET images were analyzed by semi-quantitative standard uptake value (SUV) only and (or) SUV plus visual observation. Focuses with a SUV > 2.5 were judged as malignant changes, while SUV < or = 2.5 was judged as benign. SUV plus visual analysis, based on the focal SUV, the nodular size and shape, and clinical data, was carried out by two nuclear doctors. CT imaging was interpreted by two radiological doctors. The sensitivity, specificity, accuracy, positive predictive and negative predictive values of 18F-FDG PET and CT in the diagnosis, and in the evaluation of lymphatic metastasis and remote metastasis of lung lesions were calculated. The diagnostic efficiency of the two methods (SUV or visual plus SUV method) was compared. (1) 58 cases were confirmed to be malignant by surgery or pathological examination, while 36 cases were proved benign by pathology or empirical therapy. (2) The sensitivity, specificity, accuracy, positive and negative predictive values were 69%, 65%, 68%, 82% and 49% respectively for CT; and 91%, 89%, 90%, 93% and 87% respectively for SUV analysis; and 95%, 94%, 95%, 97% and 92% respectively for visual plus SUV methods. (3) Among 34 patients with mediastinal lymph node involvement confirmed by pathology, 18F-FDG PET detected 30 cases, while CT detected only 18 cases (P < 0.01). (4) 18F-FDG PET revealed 19 cases with distant metastases, while CT only discovered 8 cases with distant metastases. As a result, the therapy was modified by PET examination in 14 patients. 18F-FDG PET imaging is of important clinical value in the diagnosis of lung lesions and the staging of malignancy.Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 03/2005; 28(2):108-11.