Rika Fukui,
Fumitake Hata,
Takahiro Yasoshima,
Toshio Honma,
Hiroki Nomura,
Kenichi Sasaki,
Hidefumi Nishimori,
Kazunori Sasaki,
Goro Kutomi,
Keisuke Ohno, Ikuo Oikawa,
Kazuaki Sasaki,
Ken Tarumi,
Yuuji Ishiyama,
Kenji Kobayashi,
Naoya Yamamoto,
Koichi Hirata
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ABSTRACT: Four cases of anorectal malignant melanoma are reported in this paper. All patients underwent an abdominoperineal resection with lymph node dissection for a curative operation and received postoperative chemotherapy with dacarbazine, ranimustine, and vincristine, either with or without interferon-beta. One of these patients has been observed for more than 6 years postoperatively without any evidence of recurrence. The other three patients had advanced diseases at the time of diagnosis, and died within 3 years after operation. The prognosis of anorectal malignant melanoma is considered to be directly related to tumor size and depth. Therefore, a staging system and treatments based on the tumor size and depth (or thickness) are needed.
Surgery Today 02/2002; 32(6):555-8. · 1.22 Impact Factor