Guido Meissner

Publications of Guido Meissner

• Comparison of prevalence of microorganisms on titanium and silicone/polymethyl methacrylate obturators used for rehabilitation of maxillary defects.

  Authors: Rita A Depprich, Jorg G Handschel, Ulrich Meyer, Guido Meissner

  The Journal of prosthetic dentistry. 06/2008; 99(5):400-5.

  STATEMENT OF PROBLEM: Silicone or polymethyl methacrylate obturators, used for rehabilitation of maxillary defects, bear the risk of an enhanced settlement of microorganisms and, therefore, imposeSTATEMENT OF PROBLEM: Silicone or polymethyl methacrylate obturators, used for rehabilitation of maxillary defects, bear the risk of an enhanced settlement of microorganisms and, therefore, impose the risk of local or systemic infections. Titanium-based obturators offer favorable characteristics in contrast to polymer-based protheses in terms of microbial biofilm formation. PURPOSE: The purpose of this study was to compare the prevalence of microorganisms on titanium and silicone/PMMA (polymethyl methacrylate) obturators used for rehabilitation of maxillary defects. MATERIAL AND METHODS: The obturators of 36 patients (17 titanium based, 19 polymer based) who underwent maxillectomy due to malignancy were evaluated. Microbiological specimens from obturator surfaces, the adjacent mucous surfaces, and the interior of polymer-based obturators were obtained with a sterile swab. Microbiological analysis was performed using conventional methods, including microscopy and culture, on several agar media. For statistical data analysis, Fisher's exact test (FT) (alpha=.05) and odds ratio (OR) (95% confidence interval) were used. RESULTS: Polymer-based obturators showed a significantly higher quantitative and qualitative presence of nonphysiological microorganisms compared to titanium obturators. There is a significant risk (factor 1.4) for the penetration of bacteria to the depths of polymer-based obturators, especially if the surface is contaminated by pathological bacteria (P=.02). CONCLUSIONS: The use of titanium-based obturators for the oral rehabilitation of postmaxillectomy patients significantly reduces the risk of infections with pathogenic oral microorganisms and, therefore, may protect patients from local oral or systemic infections.

• Comparison of prevalence of microorganisms on titanium and silicone/polymethyl methacrylate obturators used for rehabilitation of maxillary defects

  Authors: Rita A. Depprich, Jorg G. Handschel, Ulrich Meyer, Guido Meissner

  The Journal of Prosthetic Dentistry.

  Statement of problemSilicone or polymethyl methacrylate obturators, used for rehabilitation of maxillary defects, bear the risk of an enhanced settlement of microorganisms and, therefore, impose theStatement of problemSilicone or polymethyl methacrylate obturators, used for rehabilitation of maxillary defects, bear the risk of an enhanced settlement of microorganisms and, therefore, impose the risk of local or systemic infections. Titanium-based obturators offer favorable characteristics in contrast to polymer-based protheses in terms of microbial biofilm formation.PurposeThe purpose of this study was to compare the prevalence of microorganisms on titanium and silicone/PMMA (polymethyl methacrylate) obturators used for rehabilitation of maxillary defects.Material and methodsThe obturators of 36 patients (17 titanium based, 19 polymer based) who underwent maxillectomy due to malignancy were evaluated. Microbiological specimens from obturator surfaces, the adjacent mucous surfaces, and the interior of polymer-based obturators were obtained with a sterile swab. Microbiological analysis was performed using conventional methods, including microscopy and culture, on several agar media. For statistical data analysis, Fisher's exact test (FT) (α=.05) and odds ratio (OR) (95% confidence interval) were used.ResultsPolymer-based obturators showed a significantly higher quantitative and qualitative presence of nonphysiological microorganisms compared to titanium obturators. There is a significant risk (factor 1.4) for the penetration of bacteria to the depths of polymer-based obturators, especially if the surface is contaminated by pathological bacteria (P=.02).ConclusionsThe use of titanium-based obturators for the oral rehabilitation of postmaxillectomy patients significantly reduces the risk of infections with pathogenic oral microorganisms and, therefore, may protect patients from local oral or systemic infections. (J Prosthet Dent 2008;99:400-405)