Fukushima Y.

Publications (2)2.39 Total impact

• Article: Myelodysplastic syndrome in a child with 15q24 deletion syndrome.

  Narumi Y, Shiohara M, Wakui K, Hama A, Kojima S, Yoshikawa K, Amano Y, Kosho T, Fukushima Y.
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  ABSTRACT: 15q24 deletion syndrome is a recently-described chromosomal disorder, characterized by developmental delay, growth deficiency, distinct facial features, digital abnormalities, loose connective tissue, and genital malformations in males. To date, 19 patients have been reported. We report on a 13-year-old boy with this syndrome manifesting childhood myelodysplastic syndrome (MDS). He had characteristic facial features, hypospadias, and mild developmental delay. He showed neutropenia and thrombocytopenia for several years. At age 13 years, bone marrow examination was performed, which showed a sign suggestive of childhood MDS: mild dysplasia in the myeloid, erythroid, and megakaryocytic cell lineages. Array comparative genomic hybridization (array CGH) revealed a de novo 3.4 Mb 15q24.1q24.3 deletion. Although MDS has not been described in patients with the syndrome, a boy was reported to have acute lymphoblastic leukemia (ALL). The development of MDS and hematological malignancy in the syndrome might be caused by the haploinsufficiency of deleted 15q24 segment either alone or in combination with other genetic abnormalities in hematopoietic cells. Further hematological investigation is recommended to be beneficial if physical and hematological examination results are suggestive of hematopoietic disturbance in patients with the syndrome. © 2011 Wiley-Liss, Inc.
  American Journal of Medical Genetics Part A 01/2011; · 2.39 Impact Factor
• Source

  Available from: hindawi.com

  Article: Applications of Cu@C Nanoparticles in New Dye-Sensitized Solar Cells

  Liao Chang-Yu, H Paul Wang, Chen F.-L, Huang C.-H, Fukushima Y
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  ABSTRACT: To enhance the efficiency of a newly developing dye-sensitized solar cell (DSSC), the Cu@C (Cu size=7 and 20 nm) core-shell nanoparticles-dispersed molten salt-conjugated electrolyte has been studied. Experimentally, the efficiencies (η) of the DSSC are in the range of 2.70–4.09% with a short-circuit photocurrent density (JSC) of 5.775–9.910 mA/cm2. Interestingly, it is found that dispersion of 1% of the Cu@C (Cu size=7 nm) nanoparticles in the molten salt-(1,2-dimethyl-3-propylimidazolium iodide (DMPII)) conjugated electrolyte results in an enhancement (about 11%) of the η (4.06%). Greater fractions (3–10%) of the Cu@C nanoparticles dispersed in the molten salt cause a poor performance (lower JSC and η) of the DSSC possibly due to interference of the internal electron transportation routes in the DSSC by oxidation of Cu with I2 originally in the electrolyte.
  Journal of Nanomaterials. 01/2009;