Fazaa Becima

Publications (3)2.72 Total impact

• Article: Linear IgA bullous dermatosis in tunisian children: 31 cases.

  Kharfi Monia, Khaled Aida, Karaa Amel, Zaraa Ines, Fazaa Becima, Kamoun Mohamed Ridha
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  ABSTRACT: Linear IgA bullous dermatosis (LAD) of children is relatively frequent in Africa. We undertook this study to evaluate the frequency of this disease among autoimmune bullous diseases (AIBDs) in Tunisian children. We present a 32-year retrospective study (January 1976 to December 2007). Children with chronic acquired bullous diseases seen at the Charles Nicolle Hospital of Tunis and for who direct immunofluorescence (DIF) of the perilesional skin demonstrated linear IgA immunoglobulin deposits were included in the study population. Thirty-one children with LAD were selected representing 65.9% of all AIBDs of children selected in the same period, with a mean age of 5.5 years and a sex ratio (M/F) of 2.4. Most of the children had generalized eruption (28/31), more profuse on the face, pelvic region, buttocks and limbs. Mucosal lesions happened in only four children (12.9%). The mean duration of the disease was 14 months. DIF demonstrated linear IgA deposits along the dermal-epidermal junction in all patients. IgG, IgM, and complement were also seen (20/31). Indirect immunofluorescence was negative in 67% of cases. Eight patients responded to dapsone; however, prednisone had to be added in seven children to control the disease and erythromycin in four others. A long-term remission period was achieved in 76.1% of patients. This study confirms that LAD is the most common AIBD in children in Tunisia which frequently occurs in preschool-aged males. Independently of the used drug, a long-term remission is frequently observed.
  Indian Journal of Dermatology 03/2011; 56(2):153-9.
• Article: Pigmented mammary Paget's disease mimicking melanoma a further case in a man.

  Zeglaoui Faten, Khaled Aida, Fazaa Becima, Hchich Monia, Ben Romdhane Khaled, Kamoun Mohamed Ridha
  The Breast Journal 06/2009; 15(4):420-1. · 1.64 Impact Factor
• Article: Agminated Spitz nevi arising on a nevus spilus after chemotherapy.

  Khaled Aida, Kharfi Monia, Sellami Ahlem, Hamel-Teillac Dominique, Fazaa Becima, Fraitag Sylvie, Kamoun Mohamed Ridha
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  ABSTRACT: Agminated Spitz nevus arising on a background of nevus spilus (NS) is a rare condition. We report here a further case in a child that is original because it is induced by chemotherapy. A 3-year-old boy presented 3 months after the onset of a chemotherapy for a vesico-prostatic rhabdomyosarcoma, multiple pigmented papulo-nodules located on the face, neck, chest wall, and the higher back. These lesions have arose on a pre-existent large congenital histologically confirmed nevus spilus extending along the face, neck, the left shoulder and the left chest wall. Histological examination of three excised nodules led to the diagnosis of Spitz nevus. Our patient may have a high risk for melanoma since he has many criteria predisposing to this risk. Some of these criteria are related to NS but we should also take into account the chemotherapy induction and the high number of Spitz nevi.
  Pediatric Dermatology 27(4):411-3. · 1.07 Impact Factor