ABSTRACT: Two soft tissue masses from different locations on two dogs were submitted for histopathologic examination. Each was well demarcated and consisted of interweaving streams of bland spindle cells among which numerous plasma cells and lymphocytes were scattered. Spindle cells reacted strongly to antibodies against vimentin and calponin, while a subset of the spindle cells expressed smooth muscle actin and desmin. Immunohistochemistry results were consistent with a myofibroblastic derivation for the spindle cell population and the diagnosis of inflammatory myofibroblastic tumor (IMT) was made. This is the second report of IMT in the veterinary literature.
Veterinary Pathology 02/2009; · 1.95 Impact Factor