Publications (2)5.07 Total impact
-
Article: The effect of a non-intensive community-based lifestyle intervention on the prevalence of Metabolic Syndrome. The DEPLAN study in Greece.
[show abstract] [hide abstract]
ABSTRACT: The aim of the present study was to evaluate the effectiveness of a non-intensive, community-based, lifestyle intervention program on the prevalence of metabolic syndrome (MS), in individuals at high risk for development of type 2 diabetes (T2D). In accordance with the FINDRISC score, 191 high-risk persons for T2D, 56.3±10.8 years old, participated in a one-year lifestyle intervention program consisting of six bi-monthly sessions with a dietician. MS prevalence was assessed at baseline and one year later. The intervention was completed by 125 participants. They lost on average 1.0±4.8 kg (p=0.025) (mean±SD) and registered favourable dietary changes. The baseline prevalence of MS was similar among age groups and genders and decreased after one year (from 63.4±48.4% to 54.8±50.0%, p<0.001). In a multiple logistic regression model, younger age (p=0.009), male gender (p=0.004), improvement of the dietary score after one year (p=0.022), a lower FINDRISC score (p=0.033), a lower triglyceride level (p=0.010) and a higher baseline HDL-C level (p=0.003) were significantly and independently associated with improvement in MS status. A non-intensive lifestyle intervention program to prevent T2D is effective in decreasing the prevalence of MS in individuals at high risk for T2D development, possibly conferring multiple cardiovascular health benefits.Hormones (Athens, Greece) 07/2012; 11(3):316-24. · 2.44 Impact Factor -
Article: The association between physical activity and the development of acute coronary syndromes in diabetic subjects (the CARDIO2000 II study).
[show abstract] [hide abstract]
ABSTRACT: The prevalence of type-2 diabetes is increasing dramatically, primarily being driven by environmental factors, like dietary and exercise habits. In this study we investigated the association of physical activity and acute coronary events in diabetic patients, an issue that has not been adequately studied so far. Cross-sectional, case-control study. We studied demographic, lifestyle, dietary and clinical information in 216 hospitalized diabetic patients (171 men, 45 women) with a first event of an acute coronary syndrome and 196 frequency matched (by age and sex) diabetic controls (154 men, 42 women) without any evidence of coronary heart disease. Physical activity was evaluated according to the kcal/min expended and the weekly frequency of exercise. Physically active were considered those who reported non-occupational physical activity >once/week (at least 30 min/time). Seventy-eight (36%) of 216 patients and 110 (56%) of 196 controls were classified as physically active (P<0.001). Multivariate conditional logistic regression analysis revealed that the odds ratio for developing an acute coronary event in diabetic subjects who reported moderate levels of physical activity was 0.22 [95% confidence interval (CI): 0.12-0.47], while in those who reported vigorous physical activity it was 0.33 (95% CI: 0.21-0.59), after adjusting for age, sex, and the conventional cardiovascular risk factors. Physical activity (moderate and vigorous) seems to be associated with a lower prevalence of acute coronary events in the investigated group of diabetic subjects. Light physical activity does not seem to have any significant association with the development of acute coronary events.European Journal of Cardiovascular Prevention and Rehabilitation 09/2004; 11(4):298-303. · 2.63 Impact Factor
