V Preininger

Publications (26)49 Total impact

• Article: Separation and Quantification of Some Alkaloids from Fumaria parviflora by Capillary Isotachophoresis1.

  I Válka, D Walterová, M E Popova, V Preininger, V Simánek
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  ABSTRACT: The isotachophoretic separation of some isoquinoline alkaloids in acid-base partially purified extracts from Bulgarian FUMARIA PARVIFLORA was studied. The electrolyte system for model mixtures of alkaloids (-)-stylopine, (-)-canadine, coptisine, berberine, protopine, cryptopine, chelidonine, bulbocapnine, papaverine, parfumine and for the plant extracts contained the leading ion K (+) (0.01 M), counter ion CH (3)COO (-), pH (L) 5.5, and the terminating ion H (+) (acetic acid 0.01 M). In the plant extracts, protopine and parfumine were quantitatively determined during F. PARVIFLORA growth and development in the term May-June 1984.
  Planta Medica 09/1985; 51(4):319-22. · 2.15 Impact Factor
• Article: Alkaloids of Corydalis cheilanthifolia1.

  P Oroszlán, L Dolejs, V Simánek, V Preininger
  Planta Medica 07/1985; 51(3):286. · 2.15 Impact Factor
• Article: Alkaloids from Seeds of Iphigenia stellated1.

  H Potesilová, S Dvorácková, V Preininger, V Simánek
  Planta Medica 03/1985; 51(1):72. · 2.15 Impact Factor
• Article: Practical application of isotachophoresis in analysis of isoquinoline alkaloids.

  D Walterová, Z Stránský, V Preininger, V Simánek
  Acta Universitatis Palackianae Olomucensis Facultatis Medicae 02/1985; 111:23-36.
• Article: Qualitative and quantitative isotachophoretic analysis of some quaternary isoquinoline alkaloids1,2.

  D Walterová, V Preininger, V Simánek
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  ABSTRACT: A rapid isotachophoretic separation of benzo[ C]phenanthridine alkaloids from CHELIDONIUM MAJUS L. is described. The method allows the determination of sanguinarine and chelerythrine in the presence of other isoquinoline alkaloids in crude alkaloids extracts.
  Planta Medica 05/1984; 50(2):149-51. · 2.15 Impact Factor
• Article: Isoquinoline alkaloids in local periodontal disease therapy (preliminary notice).

  H Cerná, B Fiala, J Lenfeld, E Marsálek, V Preininger, V Simánek
  Acta Universitatis Palackianae Olomucensis Facultatis Medicae 02/1984; 107:159-62.
• Article: Inhibition of butyrylcholinesterase activity by some isoquinoline alkaloids.

  J Ulrichová, D Walterová, V Preininger, V Simánek
  Planta Medica 08/1983; 48(3):174-7. · 2.15 Impact Factor
• Article: Alkaloids of Fumaria densiflora*.

  M E Popova, V Simánek, J Novák, L Dolejs, P Sedmera, V Preininger
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  ABSTRACT: FUMARIA DENSIFLORA DC., collected near Varna (Bulgaria) was investigated for its alkaloidal content. Protopine, cryptopine, coptisine, palmatine, adlumidiceine, (+/-)-sinactine, and a new spirobenzylisoquinoline alkaloid densiflorine were isolated. Benzophenanthridine alkaloids were not detected.
  Planta Medica 08/1983; 48(8):272-4. · 2.15 Impact Factor
• Article: Inhibition of butyrylcholinesterase activity by some isoquinoline alkaloids.

  J Ulrichová, D Walterová, V Preininger, V Simánek
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  ABSTRACT: The inhibition of butyrylcholinesterase activity in human serum by protoberberine, benzophenanthridine and aporphine alkaloids as well as four model compounds has been studied. The mechanism of the inhibition is discussed on the basis of the different types of interaction of these compounds with butyrylcholinesterase and acetylcholinesterase.
  Planta Medica 07/1983; 48(7):174-7. · 2.15 Impact Factor
• Article: Inhibition of acetylcholinesterase activity by some isoquinoline alkaloids.

  J Ulrichová, D Walterová, V Preininger, J Slavík, J Lenfeld, M Cushman, V Simánek
  Planta Medica 07/1983; 48(2):111-5. · 2.15 Impact Factor
• Article: Alkaloids from Fumaria parviflora and F. kralikii.

  M E Popova, V Simánek, L Dolejs, B Smysl, V Preininger
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  ABSTRACT: From Fumaria parviflora Lam. were isolated the major alkaloids protopine and adlumidiceine and the minor alkaloids parfumine, fumariline, dihydrofumariline, cryptopine, (-)-stylopine, 8-oxocoptisine, sanguinarine, and oxysanguinarine. The quaternary protoberberine fraction gave coptisine. Adlumidiceine, dihydrofumariline, 8-oxocoptisine, sanguinarine, and oxysanguinarine were found in F. parviflora for the first time. F. kralikii Jordan gave, besides the major alkaloids protopine, fumarophycine, and O-methylfumarophycine, the alkaloids adlumidiceine, berberine, coptisine, cryptopine, (-)-stylopine, and (-)-canadine. Only protopine and cryptopine have been isolated from F. kralikii earlier.
  Planta Medica 06/1982; 45(2):120-2. · 2.15 Impact Factor
• Article: Determination of antioxidants of the diphenylamine type in butadiene-styrene rubber (BSR).

  Z Stránský, J Vicar, V Preininger, V Simánek
  Acta Universitatis Palackianae Olomucensis Facultatis Medicae 02/1982; 103:147-53.
• Article: Antiinflammatory activity of quaternary benzophenanthridine alkaloids from Chelidonium majus.

  J Lenfeld, M Kroutil, E Marsálek, J Slavík, V Preininger, V Simánek
  Planta Medica 11/1981; 43(2):161-5. · 2.15 Impact Factor
• Article: Inhibition of liver alanine aminotransferase activity by some benzophenanthridine alkaloids.

  D Walterová, Ulrichová, V Preininger, V Simánek, J Lenfeld, J Lasovský
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  ABSTRACT: The quaternary benzophenanthridine alkaloids sanguinarine (1) and chelerythrine (2) inhibit rat liver L-alanine-:2-oxoglutarate aminotransferase (EC 2.6.1.2) activity. Nitidine (3) has no inhibitory effect. The inhibitory activity of alkaloids depends on the reactivity of the iminium bond with the nucleophilic reagent, e.g., the thiol group. The stability constants of adduct formation for thioethanol, cysteine, and glutathione with sanguinarine (1) and chelerythrine (2) are given. The mechanism of the inhibition of alanine aminotransferase activity by the alkaloids 1 and 2 is discussed.
  Journal of Medicinal Chemistry 10/1981; 24(9):1100-3. · 5.25 Impact Factor
• Article: Transformation of alkaloids of the Colchicine type in leaves and flowers of Colchicum autumnale and C. byzantinum.

  F Santavý, V Preininger, V Simánek, H Potesilová
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  ABSTRACT: It was found that the so far described variations in the content of colchicine alkaloids in leaves and flowers of Colchicum autumnale L. and C. byzantinum Ten. are due to enzymatic O-demethylation and degradation of colchicine (I), N-deacetyl-N-formylcolchicine (XI), and demecolcine (XVII) during drying and storing of the plant material. A simplified method was elaborated to separate the neutral, phenolic, basic, and basic-phenolic fractions of tropolone alkaloids.
  Planta Medica 10/1981; 43(2):153-60. · 2.15 Impact Factor
• Article: [Isolation and chemistry of the alkaloids from plants of the Papaveraceae, LXXXI Glauca - a new section of the genus Papaver].

  V Preininger, J Novák, F Santavý
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  ABSTRACT: On the basis of alkaloidal, morphological and chromosomal studies, the section Mecones Bernh. (Syn.: Papaver L., sect. Papaver) has been subdivided into two sections. Thus the new section Glauca J. Novak includes the species Papaver glaucum Boiss. et Hausskn., P. gracile Auch. and P. decaisnei Hochst. et Steud., whereas the section mecones Bernh. only the species P. somniferum L. and P. setigerum Dc. The major alkaloids of the species of the section mecones are the morphinane alkaloids morphine and codeine, whereas those of the section Glauca the rhoeadine and the papaverrubines. The section mecones has the basic chromosome number x = 11, and the section Glauca x = 7. The basic chromosome numbers have been correlated with the morphological features.
  Planta Medica 02/1981; 41(2):119-23. · 2.15 Impact Factor
• Article: Alkaloids from leaves and flowers of colchicum autumnale L.

  V Malichová, H Potĕsilová, V Preininger, F Santavý
  Planta Medica 07/1979; 36(2):119-27. · 2.15 Impact Factor
• Article: [Electrolytic status, acidobasic equilibrium, and buffer capacity of the semen in man (author's transl)].

  J Bartek, V Preininger, F Santavý
  Bratislavske lekarske listy 05/1978; 69(4):386-401. · 0.40 Impact Factor
• Article: Isolation and chemistry of alkaloids from plants of the family Papaveraceae LXVII: Corydalis cava (L.) Sch. et K. (C. tuberosa DC).

  V Preininger, R S Thakur, F Santavý
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  ABSTRACT: From Corydalis cava (L.) Sch. et K. (C. tuberosa DC) (Papaveraceae: genus Corydalis Med.), a mixture of alkaloids (0.53%) was isolated. The main alkaloid was (+)-bulbocapnine, and the minor alkaloids were coptisine, (+)-domestine, adlumidiceine, (+)-predicentrine, protopine, (-)-capnoidine, (+)-stylopine, (+)-isoboldine, 8-oxocoptisine, 1,2-methylenedioxy-6a,7-dehydroaporphine-10,11-quinone, and corysamine. In addition, fumaric acid was obtained. Coptisine, adlumidiceine, predicentrine, 8-oxocoptisine, corysamine, 1,2-methylenedioxy-6a, 7-dehydroaporphine-10,11-quinone, and isoboldine were found in C. cava for the first time, but rhoeadine and papaverrubine alkaloids were not detected. Predicentrine and isoboldine were identified on the basis of the UV, IR, mass, and PMR spectra.
  Journal of Pharmaceutical Sciences 03/1976; 65(2):294-6. · 3.06 Impact Factor
• Article: [Isolation and identification of the alkaloids in papaver radicatum (author's transl)].

  H Böhm, L Dolejs, V Preininger, F Santavý, V Simánek
  Planta Medica 12/1975; 28(3):210-4. · 2.15 Impact Factor