Atushi Noguchi

Publications (1)1.5 Total impact

• Source

  Available from: jsnm.org

  Article: A case of malignant pheochromocytoma with early intense uptake and immediate rapid washout of 99mTc-tetrofosmin characterizing the overexpression of anti-apoptotic Bcl-2.

  Shigetoshi Wakasugi, Toshiaki Kinouchi, Haruo Taniguchi, Kunihiko Yokoyama, Kazuki Fukuchi, Atushi Noguchi, Masanori Takeshita, Terumi Hashizume
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  ABSTRACT: Defective apoptotic program due to the overexpression of the anti-apoptotic Bcl-2 protein of the outer mitochondrial membrane may be a cause of the poor response of malignant pheochromocytoma to 131I-MIBG therapy. We report a case of malignant pheochromocytoma which showed early intense uptake and immediate rapid washout of 99mTc-tetrofosmin characterizing the overexpression of anti-apoptotic Bcl-2 and which was refractory to 131I-MIBG therapy.
  Annals of Nuclear Medicine 06/2006; 20(4):325-8. · 1.50 Impact Factor