Domit Azar

Publications (8)16.01 Total impact

• Article: Ockham's razor revisited: decreased visual acuity secondary to keratoconus in a patient with intracranial hypertension.

  Adrian T Fung, Domit Azar, Samantha Fraser-Bell, Peter McCluskey, John Grigg
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  ABSTRACT: Both intracranial hypertension and keratoconus may be associated with visual impairment. The authors present a case of a young female with poor right vision that did not improve despite treatment of her intracranial hypertension. Ophthalmic consultation diagnosed keratoconus as the cause.
  Case Reports 01/2011; 2011.
• Article: Graft-free Molteno tube insertion: 10-year outcomes.

  Lia Rossiter-Thornton, Domit Azar, James Leong, Susan Lightman, Hamish M A Towler, Peter McCluskey
  The British journal of ophthalmology 05/2010; 94(5):665-6. · 2.92 Impact Factor
• Article: Q fever-associated HLAB27 anterior uveitis.

  Lia Rossiter-Thornton, Michael Rossiter-Thornton, Domit Azar
  Clinical and Experimental Ophthalmology 12/2008; 36(8):797-8. · 1.98 Impact Factor
• Article: Pars plana vitrectomy for the management of retained lens material after cataract surgery.

  Rohan Merani, Alex P Hunyor, T Justin Playfair, Andrew Chang, John Gregory-Roberts, Alex B L Hunyor, Domit Azar, Robert G Cumming
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  ABSTRACT: To evaluate the management and outcomes of patients undergoing pars plana vitrectomy (PPV) for retained lens material after cataract surgery; and to evaluate risk factors for poor visual outcome, retinal detachment, raised intraocular pressure (IOP), and cystoid macular edema (CME). Retrospective interventional consecutive case series. setting: Institutional and Clinical practice. study population: Patients with retained lens material after cataract surgery who underwent vitrectomy at Sydney Eye Hospital between July 1, 1998 and October 31, 2003. intervention: Standard three-port PPV/lensectomy. main outcome measures: Final best-corrected visual acuity (BCVA), retinal detachment, raised IOP, and CME. A total of 223 eyes of 223 patients were included, with a mean follow-up of 20.5 months after vitrectomy. Final BCVA was 6/12 or better in 159 patients (71.3%). Retinal detachment occurred in 20 patients (9%), with 11 diagnosed before or during vitrectomy, and nine occurring after vitrectomy. Ten patients (5.0%) developed raised IOP and 42 (23.2%) developed CME. Poor final visual acuity was associated with retinal detachment (P = .0026), and with poor visual acuity at presentation (P = .030). There was a significant association between retinal detachment and a long interval (>30 days) between cataract surgery and vitrectomy (P = .00047) and between retinal detachment and younger age (P = .0070). Visual acuity results in this study compared favorably with previously published reports. Although the overall rate of retinal detachment was low, it was significantly higher in those with a delayed interval between cataract surgery and vitrectomy, and was significantly associated with a poorer visual outcome.
  American Journal of Ophthalmology 10/2007; 144(3):364-70. · 4.22 Impact Factor
• Article: Retinoblastoma in New South Wales 1975 to 2001.

  Domit Azar, Craig Donaldson, Freny Kalapesi, Robert Cumming
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  ABSTRACT: To examine the epidemiology of retinoblastoma in New South Wales (NSW), from 1975 to 2001, comparing the incidence with other parts of the developed world. Examination of medical files for patients presenting to NSW retinoblastoma treatment centers between 1975 and 2001. Comparisons to international data were made. One hundred twenty-eight patients [63 (49.2%) male and 65 (51.8%) female] presented. The mean annual incidence of retinoblastoma in NSW was 8 per million children aged 0 to 6 years, per year. The incidence of retinoblastoma in NSW is similar to other parts of the developed world.
  Journal of Pediatric Hematology/Oncology 11/2006; 28(10):642-6. · 1.16 Impact Factor
• Article: Paediatric uveitis: a Sydney clinic experience.

  Domit Azar, Frank Martin
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  ABSTRACT: The aim of this study was to retrospectively review uveitis cases at The Children's Hospital at Westmead, Sydney, since its inception in 1997 to 2001, including patients presenting at the Camperdown, Sydney, campus between 1989 and 1997 attending Westmead for further care. Comparison is made with international centres. Information was obtained from medical records. Forty patients (53 eyes) presented, of whom 23 (57.5%) were female and 17 (42.5%) were male (mean age 6.7 years). Of 53 eyes, 35 (66%) had anterior uveitis, three (5.7%) intermediate uveitis, seven (13.2%) posterior uveitis and eight (15.1%) panuveitis. Twenty-seven (67.5%) patients had disease unilaterally and 13 (32.5%) bilaterally. Twenty-four (60%) cases were idiopathic. Seven (17.5%) cases were associated with juvenile rheumatoid arthritis, three (7.5%) with herpes zoster, two (5%) with herpes simplex, two (5%) with toxocara, one (2.5%) with toxoplasma, and one (2.5%) with ulcerative colitis. Complications included cataract in 14 (26.4%) eyes; band keratopathy in four (7.5%) eyes; macular scarring in three (5.7%) eyes; and glaucoma in four (7.5%) eyes. Last measured acuity was 6/6 for 19 (35.8%) eyes, < or =6/18 for 15 (28.3%) eyes and <6/60 for eight (15.1%) eyes. Despite small numbers, the comparisons of this study with some international studies, and its contrasts with other studies, are due to similarities and differences amongst these studies with respect to factors of referral bias, and the aetiological basis of disease.
  Clinical and Experimental Ophthalmology 11/2004; 32(5):468-71. · 1.98 Impact Factor
• Article: Questioning the need for routine bone marrow aspiration and lumbar puncture in patients with retinoblastoma.

  Domit Azar, Craig Donaldson, Luciano Dalla-Pozza
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  ABSTRACT: This study assesses the value of routinely investigating children with retinoblastoma with bone marrow aspiration and lumbar puncture, staging investigations not without risk and trauma to the patient, emotional stress on parents and financial cost to the community. Medical files and specimens were obtained and examined for patients with retinoblastoma presenting to the Royal Alexandra Hospital for Children, Camperdown and the Children's Hospital at Westmead, Sydney, from 1975 to 2001. In total, 123 patients presented; 62 (50.4%) were boys and 61 (49.6%) were girls. Of these 123 patients, 74 (60.2%) had unilateral disease, 46 (37.4%) involving the left eye and 28 (22.8%) involving the right eye. There were 47 (38.2%) patients with bilateral disease, and two (1.6%) with trilateral disease. Mean age of presentation was 17.9 months (23.1 months for unilateral subjects; 10.3 months for bi-lateral subjects; 3.5 months for trilateral subjects). There were 13 (10.6%) with a positive family history. Of 74 unilateral subjects, 70 (94.6%) required enucleation and four (5.4%) were salvaged. Of 47 bilateral subjects, 13 (27.7%) did not require enucleation, 27 (57.4%) required unilateral enucleation and seven (14.9%) required bilateral enucleation. Both trilateral subjects died. Of all 123 subjects, 112 (91.1%) had bone marrow aspiration and lumbar puncture performed during initial assessment, and none showed evidence of malignancy. Given the small but significant risks associated with these procedures, the results of this study cannot support bone marrow aspiration and lumbar puncture as routine investigations in all patients presenting with retinoblastoma, suggesting a more limited usage of these investigations is warranted.
  Clinical and Experimental Ophthalmology 03/2003; 31(1):57-60. · 1.98 Impact Factor
• Article: Brimonidine-induced anterior uveitis and conjunctivitis: clinical and histologic features.

  Ethan V Nguyen, Domit Azar, Daya Papalkar, Peter McCluskey
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  ABSTRACT: Brimonidine tartarate is a selective alpha2-adrenergic receptor agonist that is indicated for use in the treatment of glaucoma and ocular hypertension. Since its introduction in 1997 there have been a small number of case reports concerning granulomatous anterior uveitis as a late adverse reaction to long-term brimonidine therapy. We report a case of bilateral anterior uveitis and granulomatous papillary conjunctivitis in a 78-year-old gentleman after 2 years of brimonidine therapy. Cessation of brimonidine lead to rapid termination of uveitis. The histologic features of the conjunctiva are described. This has not been previously reported.
  Journal of Glaucoma 17(1):40-2. · 1.78 Impact Factor