Publications (4)0.47 Total impact
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Article: [Prevalence of anti-HCV antibodies and seroconversion incidence in five haemodialysis units in Morocco].
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ABSTRACT: Dialysis patients are among groups at risk for development of hepatitis C infection (HCV). The aim of the study was to evaluate the prevalence and the incidence of seroconversion for HCV in five haemodialysis units in Morocco. The study was conducted during the period from September 2003 to September 2004. We studied 303 patients (148 females), mean age 49+/-16 years; dialysis duration was higher than five years in 64% of the cases. The prevalence of HCV infection was evaluated by using a fourth generation enzyme immunoassays. In the seronegative patients, we performed anti-HCV tests at three and six months intervals and monthly testing of alanine aminotransferase (ALT) activity and assessment of anti-HCV tests if the ALT activity was elevated. Moreover, risk factors, such as blood transfusion, surgery and other invasive procedures were recorded. Seroprevalence of HCV was 68.3%. Among 85 patients who were tested negative for anti-HCV at the entry of the study, four (4.60%) seroconverted in six month (estimated incidence: 9.41 new cases per year). HCV seropositivity was associated with longer duration of dialysis (p=0.000), and previous blood transfusions (p=0.047). The follow-up of the ALT in the seronegative patients did not show any significant variation. In conclusion, the prevalence and incidence of HCV infection in haemodialysis units in Morocco are dramatically elevated. High incidence seropositivity suggested nosocomial transmission of HCV; the dialysis processes itself, and blood transfusions are important risk factors for HCV transmission in these patients.Néphrologie & Thérapeutique 05/2008; 4(2):105-10. · 0.47 Impact Factor -
Article: Renal Replacement therapy in Morocco
Saudi Journal of Kidney Diseases and Transplantation. 01/1999; -
Article: Enuresis: epidemiological study in moroccan children.
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ABSTRACT: Enuresis is a common symptom that leads to significant psychosocial sequalae. In this study we analyzed three surveys in three different urban and suburban regions in Morocco in order to evaluate the epidemiological characteristics and profiles of the young patients who had enuresis and the attitudes of their parents towards this problem. There were 1,520 children and adolescents in this analysis whose age ranged between 5 and 15 years. They were attending various outpatient surgical and medical clinics when their parents were asked to answer a pre-prepared questionnaire. The prevalence of enuresis was 35% with preponderance of males (54%). The cause could not be defined (primary) in 91.5% of the patients with enuresis. There were familial factors associated with enuresis that included history of enuresis in the parents or siblings in 56% of the cases and coercion attitude of the parents in 23%. Enuresis was associated with impediment of learning in 23% and chastisement of children in 85.4% of the cases. Twenty three percent of the patients also had chronic organic disorders. The parents were concerned mostly when the children approached puberty or when enuresis was secondary to another problem. Spontaneous improvement was the rule by adolescence, hence only 8.7% sought medical advice for enuresis. Treatment was conventional in 67% of the cases and confined to restriction of fluids and food items in 73% of the treated patients. We conclude that enuresis is apparently higher in Moroccan children compared to reports from other countries. However, enuresis was not considered a major medical problem of concern to parents who rarely sought medical advice for it.Saudi journal of kidney diseases and transplantation: an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 13(2):151-4. -
Article: Acute renal failure in moroccan children.
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ABSTRACT: To evaluate the etiology and prognosis of acute renal failure (ARF) in Moroccan children, we retrospectively studied 120 cases of ARF that presented to two centers in Casablanca, Morocco between 1982 and 1999. There were 72 (60%) boys and 48 (40%) females with age that ranged between six months and 15 years with a mean of 6.8 +/- 5.0 years. All patients received appropriate medical treatment, while 76 (74%) patients required dialysis; peritoneal dialysis in 31 (40%) patients and hemodialysis in 45 (60%). Emergency dialysis was performed in 37 (48.7%) patients due to severe sodium and water overload and/or severe hyperkalemia, while dialysis was initiated in 39 (51.3%) because of high blood urea and creatinine levels. Predialysis serum urea nitrogen (BUN) exceeded 33 mmol/l in all of these cases and the mean was 51 mmol/l. The causes of ARF included acute glomerulonephritis (GN) in 61 (50.8%), hemolytic uremic syndrome (HUS) in 18 (15%), renal hypoperfusion in 12 (10%), acute interstitial nephritis in 9 (7.5%), urinary tract obstruction in 7 (5.9%) and the cause was not identified in 13 (10.8%). Mortality rate was 17%; recovery rate was higher in the non-oliguric patients. Outcome was favorable in 65% of the patients with glomerular disease. Most patients in this study did not require intensive care and none had neonatal ARF, which is known to carry poor prognosis.Saudi journal of kidney diseases and transplantation: an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 13(1):66-70.
