Publications (32)76 Total impact
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Dataset: Wiswede Taubner Münte Roth et al (2011) PLoS ONE Neurophysiological Correlates of Laboratory-Induced Aggression in Young Men with and without a History of Violence
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Article: Mentalisierung und externalisierende Verhaltensstörungen in der Adoleszenz
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ABSTRACT: Soziale Kognitionen sind die Grundlage für ein erfolgreiches soziales Miteinander. Externalisierende Verhaltensstörungen zeichnen sich durch ein Scheitern des zwischenmenschlichen Umgangs aus; deshalb erweist sich die Betrachtung der Rolle der sozialen Kognition als fruchtbar zum Verständnis externalisierender Symptome sowie ihrer Ätiologie und Behandlungsmöglichkeiten. In dem vorliegenden Beitrag wird zunächst die klinische Theorie der Mentalisierung erläutert und dann mit den Forschungsergebnissen zu externalisierenden Verhaltensstörungen im Feld der „theory of mind“ und zur sozialen Informationsverarbeitung verbunden. Es zeigt sich, dass je nach Ausprägung proaktiver bzw. reaktiver Aggressivität unterschiedliche Defizite der sozialen Kognition dokumentiert werden. Allerdings ist die Lebensphase der Adoleszenz trotz der maßgeblichen Veränderung der sozialen Kognition, die auch neurobiologisch belegt ist, bislang wenig untersucht worden. Daher wird eine Analyse von zwei Studien vorgestellt, die Mentalisierungsfähigkeiten von spätadoleszenten Gewalttätern mit den reflexiven Fähigkeiten einer Kontrollgruppe vergleichen. Hierzu wurden Adult Attachment Interviews mit 42 jungen Männern geführt, die nach der Reflective Functioning Scale ausgewertet wurden. Es zeigt sich, dass Gewalttäter signifikant schlechter mentalisieren können als eine gleichaltrige Kontrollgruppe. Dies ist unabhängig von der Intelligenz der Teilnehmer. Instrumentell proaktive Aggression und psychopathische Tendenzen weisen ebenfalls einen deutlichen Zusammenhang zu niedrigen reflexiven Fähigkeiten auf. Die Ergebnisse verweisen auf die Bedeutsamkeit eines Therapieangebots für externalisierende Verhaltensstörungen in der Adoleszenz, das Mentalisierungsfähigkeiten fördert. Social cognition creates the conditions for successful human interaction. Externalizing disorders are characterized by a failure of adequate social cooperation. Therefore, social cognition seems to be a key factor in understanding externalizing behavior, its etiology and treatment options. The present article combines the clinical theory of mentalization with the state-of-the-art of empirical data on externalizing behavior and of the theory-of-mind research as well as research on social information processing. Empirical evidence suggests that there are distinct deficits in social cognition depending on the type of aggression (proactive or reactive). However, even though it is known from a neurobiological perspective that social cognition is reorganized in adolescence, research on externalizing behavior and social cognition in adolescence is limited. Hence the analysis of two studies is presented which compared reflective functioning between a group of late adolescent violent offenders and a control group. A total of 42 young men participated in the studies and were interviewed with the adult attachment interview. Interviews were coded with the reflective functioning scale. Results showed that violent offenders scored significantly lower on the reflective functioning scale than age and gender matched controls. This result is independent of intelligence. Instrumental proactive aggression and psychopathic tendencies are also strongly associated with lower reflective functioning. The results underline the importance of therapeutic interventions for externalizing adolescents which enhance reflective functioning. SchlüsselwörterSoziale Kognition-Adoleszenz-Externalisierende Verhaltensstörungen-Reflexionsfähigkeit-Defizite KeywordsSocial cognition-Adolescence-Externalizing behavioral disturbances-Reflective functions-DeficitsPsychotherapeut 04/2012; 55(4):312-320. · 0.36 Impact Factor -
Article: Evolution of the brain and intelligence in primates.
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ABSTRACT: Primates are, on average, more intelligent than other mammals, with great apes and finally humans on top. They generally have larger brains and cortices, and because of higher relative cortex volume and neuron packing density (NPD), they have much more cortical neurons than other mammalian taxa with the same brain size. Likewise, information processing capacity is generally higher in primates due to short interneuronal distance and high axonal conduction velocity. Across primate taxa, differences in intelligence correlate best with differences in number of cortical neurons and synapses plus information processing speed. The human brain stands out by having a large cortical volume with relatively high NPD, high conduction velocity, and high cortical parcellation. All aspects of human intelligence are present at least in rudimentary form in nonhuman primates or some mammals or vertebrates except syntactical language. The latter can be regarded as a very potent "intelligence amplifier."Progress in brain research 01/2012; 195:413-30. · 3.04 Impact Factor -
Article: Changes in prefrontal-limbic function in major depression after 15 months of long-term psychotherapy.
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ABSTRACT: Neuroimaging studies of depression have demonstrated treatment-specific changes involving the limbic system and regulatory regions in the prefrontal cortex. While these studies have examined the effect of short-term, interpersonal or cognitive-behavioural psychotherapy, the effect of long-term, psychodynamic intervention has never been assessed. Here, we investigated recurrently depressed (DSM-IV) unmedicated outpatients (N = 16) and control participants matched for sex, age, and education (N = 17) before and after 15 months of psychodynamic psychotherapy. Participants were scanned at two time points, during which presentations of attachment-related scenes with neutral descriptions alternated with descriptions containing personal core sentences previously extracted from an attachment interview. Outcome measure was the interaction of the signal difference between personal and neutral presentations with group and time, and its association with symptom improvement during therapy. Signal associated with processing personalized attachment material varied in patients from baseline to endpoint, but not in healthy controls. Patients showed a higher activation in the left anterior hippocampus/amygdala, subgenual cingulate, and medial prefrontal cortex before treatment and a reduction in these areas after 15 months. This reduction was associated with improvement in depressiveness specifically, and in the medial prefrontal cortex with symptom improvement more generally. This is the first study documenting neurobiological changes in circuits implicated in emotional reactivity and control after long-term psychodynamic psychotherapy.PLoS ONE 01/2012; 7(3):e33745. · 4.09 Impact Factor -
Article: Neurophysiological correlates of laboratory-induced aggression in young men with and without a history of violence.
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ABSTRACT: In order to further understand the mechanisms involved in planning an aggressive act, we conducted an event-related potential (ERP) study of young men with and without a history of violence. Participants completed a competitive reaction time task (based on the Taylor aggression paradigm) against a virtual opponent. In "passive" blocks, participants were punished by the opponent when losing the trial but could not punish, when winning, whereas in "active" blocks, participants were able to punish the opponent when winning, but were not punished when losing. Participants selected punishment strength in a decision phase prior to each reaction time task and were informed whether they had won or lost in the outcome phase. Additionally, a flanker task was conducted to assess basic performance monitoring. Violent participants selected stronger punishments, especially in "active" blocks. During the decision phase, a frontal P200 was more pronounced for violent participants, whereas non-violent participants showed an enhanced frontal negativity around 300 ms. The P200 might reflect the decision to approach the opponent at a very early state, the latter negativity could reflect inhibition processes, leading to a more considerate reaction in non-violent participants. During the outcome phase, a Feedback-Related Negativity was seen in both groups. This effect was most pronounced when losing entailed a subsequent inability to retaliate. The groups did not differ in the flanker task, indicating intact basic performance monitoring. Our data suggest that the planning of an aggressive act is associated with distinct brain activity and that such activity is differentially represented in violent and non-violent individuals.PLoS ONE 01/2011; 6(7):e22599. · 4.09 Impact Factor -
Article: Individualized and clinically derived stimuli activate limbic structures in depression: an fMRI study.
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ABSTRACT: In the search for neurobiological correlates of depression, a major finding is hyperactivity in limbic-paralimbic regions. However, results so far have been inconsistent, and the stimuli used are often unspecific to depression. This study explored hemodynamic responses of the brain in patients with depression while processing individualized and clinically derived stimuli. Eighteen unmedicated patients with recurrent major depressive disorder and 17 never-depressed control subjects took part in standardized clinical interviews from which individualized formulations of core interpersonal dysfunction were derived. In the patient group such formulations reflected core themes relating to the onset and maintenance of depression. In controls, formulations reflected a major source of distress. This material was thereafter presented to subjects during functional magnetic resonance imaging (fMRI) assessment. Increased hemodynamic responses in the anterior cingulate cortex, medial frontal gyrus, fusiform gyrus and occipital lobe were observed in both patients and controls when viewing individualized stimuli. Relative to control subjects, patients with depression showed increased hemodynamic responses in limbic-paralimbic and subcortical regions (e.g. amygdala and basal ganglia) but no signal decrease in prefrontal regions. This study provides the first evidence that individualized stimuli derived from standardized clinical interviewing can lead to hemodynamic responses in regions associated with self-referential and emotional processing in both groups and limbic-paralimbic and subcortical structures in individuals with depression. Although the regions with increased responses in patients have been previously reported, this study enhances the ecological value of fMRI findings by applying stimuli that are of personal relevance to each individual's depression.PLoS ONE 01/2011; 6(1):e15712. · 4.09 Impact Factor -
Article: Responses of the Toad Bufo bufo (L.) to Stationary Prey Stimuli1
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ABSTRACT: Abstract and SummaryIn the present work toads (Bufo bufo) are shown to respond with prey catching to stationary dummies without previous or accompanying visual or olfactory stimulation. The subjects very rarely showed jerky head movements which, therefore, cannot be necessary for perception of stationary objects. Size preference with respect to stationary stimuli is about the same as in experiments with moving stimuli. However, differences exist between the effects of stationary and moving stimuli with respect to shape and orientation. If a square measuring 10 times 10 mm and a rectangle measuring 5 times 20 mm, oriented either horizontally or vertically, are presented within the frontal-vertical plane, the square is preferred to the rectangles, and among these the horizontal rectangle is to the vertical one. This latter preference is due to the negative effect of the vertical extension: If the vertical rectangle is reduced in length, it becomes more effective as compared to the horizontal rectangle. In the horizontal (X-Z) plane the square and the rectangle oriented parallel to the Z-axis are equally superior to the bar oriented parallel to the X-axis. At presentation of a pair of stimuli in both planes, the one in the frontal-vertical plane is always preferred to that in the horizontal plane.Correspondences and differences of these results to those from experiments with moving prey dummies are discussed.Ethology 04/2010; 61(3):225 - 234. · 2.01 Impact Factor -
Article: [Neurobiological aspects of reactive and proactive violence in antisocial personality disorder and "psychopathy"].
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ABSTRACT: Impulsive-reactive violent offenders show increased autonomic activity in response to negative emotional and threatening stimuli. A volume reduction and/or activity decrease of frontal brain structures associated with impulse control and the regulation of fear and anger are likewise found in combination with a fear-related hyperactivity of the amygdala. In addition, impulsive aggression is facilitated by variants of gene polymorphisms influencing the serotonergic system. Conversely, proactive-instrumental violent offender with psychopathy, who are characterized by a lack of empathy and remorse, demonstrate an autonomic hypo-responsivity as well as dysfunctions of the amygdala and of cortical regions related to empathic and social behavior. Developmentally, aggressive children exhibit temperamental differences from early childhood on that are characteristic of a developmental pathway towards either reactive or proactive violence later in life. Exposure to negative environmental factors like ineffective parenting or childhood maltreatment has been related to a heightened risk for developing reactive violence. A developmental trajectory of proactive violence, however, has been related to a mostly genetically determined callous unemotional temperament of the child that disrupts the parental socialization efforts during childhood.Praxis der Kinderpsychologie und Kinderpsychiatrie 01/2009; 58(8):587-609. · 0.58 Impact Factor -
Article: Trait aggressiveness modulates neurophysiological correlates of laboratory-induced reactive aggression in humans.
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ABSTRACT: Reactive aggression following provocation is a frequent form of human social behavior. The neural basis of reactive aggression, especially its control, remains poorly understood, however. We conducted an event-related potential (ERP) study using a competitive reaction time task that elicits aggression through provocation. Participants were selected from a larger sample because of extreme scores in trait aggressiveness, yielding high and low trait aggressive groups. As each trial in the task is separated into a decision phase, during which the punishment level for the opponent is set, and an outcome phase, during which the punishment is applied or received, we were able to disentangle provocation-related and evaluation-related modulations of the ERPs during the aggressive interaction. Specifically, we observed an enhanced frontal negativity during the decision phase under high provocation that was positively correlated with the participants' ability to refrain from retaliation. This held true for high trait aggressive participants only, pointing to a higher need for inhibitory and control processes in these people when provoked. During the outcome phase, we detected a mediofrontal negativity in loss compared to win trials, resembling previous ERP findings to negative feedback stimuli, which have been linked to the evaluation of an outcome's valence. This mediofrontal negativity was differentially pronounced in aggressive and nonaggressive participants: Nonaggressive participants showed only a slightly smaller mediofrontal negativity in win than in loss trials, suggesting that for them punishing the opponent had a similar negative valence as being punished.Journal of Cognitive Neuroscience 09/2008; 20(8):1464-77. · 5.18 Impact Factor -
Article: Thalamo-telencephalic pathways in the fire-bellied toad Bombina orientalis.
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ABSTRACT: It was suggested that among extant vertebrates, anuran amphibians display a brain organization closest to the ancestral tetrapod condition, and recent research suggests that anuran brains share important similarities with the brains of amniotes. The thalamus is the major source of sensory input to the telencephalon in both amphibians and amniote vertebrates, and this sensory input is critical for higher brain functions. The present study investigated the thalamo-telencephalic pathways in the fire-bellied toad Bombina orientalis, a basal anuran, by using a combination of retrograde tract tracing and intracellular injections with the tracer biocytin. Intracellular labeling revealed that the majority of neurons in the anterior and central thalamic nuclei project to multiple brain targets involved in behavioral modulation either through axon collaterals or en passant varicosities. Single anterior thalamic neurons target multiple regions in the forebrain and midbrain. Of note, these neurons display abundant projections to the medial amygdala and a variety of pallial areas, predominantly the anterior medial pallium. In Bombina, telencephalic projections of central thalamic neurons are restricted to the dorsal striato-pallidum. The bed nucleus of the pallial commissure/thalamic eminence similarly targets multiple brain regions including the ventral medial pallium, but this is accomplished through a higher variety of distinct neuron types. We propose that the amphibian diencephalon exerts widespread influence in brain regions involved in behavioral modulation and that a single dorsal thalamic neuron is in a position to integrate different sensory channels and distribute the resulting information to multiple brain regions.The Journal of Comparative Neurology 07/2008; 508(5):806-23. · 3.81 Impact Factor -
Article: Sex, aggression and impulse control: an integrative account.
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ABSTRACT: There is evidence that the male sex and a personality style characterized by low self-control/high impulsivity and a propensity for negative emotionality increase the risk for impulsive aggressive, antisocial and criminal behavior. This article aims at identifying neurobiological factors underlying this association. It is concluded that the neurobiological correlates of impulsive aggression act through their effects on the ability to modulate impulsive expression more generally, and that sex-related differences in the neurobiological correlates of impulse control and emotion regulation mediate sex differences in direct aggression. A model is proposed that relates impulse control and its neurobiological correlates to sex differences in direct aggression.Neurocase 02/2008; 14(1):93-121. · 1.11 Impact Factor -
Article: Is there a structure equivalent to the mammalian basolateral amygdaloid complex in amphibians?
Journal of Anatomy 01/2008; 211(6):830; author reply 830-1. · 2.37 Impact Factor -
Article: Organization of the sensory input to the telencephalon in the fire-bellied toad, Bombina orientalis.
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ABSTRACT: The functional organization of sensory activity in the amphibian telencephalon is poorly understood. We used an in vitro brain preparation to compare the anatomy of afferent pathways with the localization of electrically evoked sensory potentials and single neuron intracellular responses in the telencephalon of the toad Bombina orientalis. Anatomical tracing showed that the anterior thalamic nucleus innervates the anterior parts of the medial, dorsal, and lateral pallia and the rostralmost part of the pallium in addition to the subpallial amygdala/ventral pallidum region. Additional afferents to the medial telencephalon originate from the thalamic eminence. Electrical stimulation of diverse sensory nerves and brain regions generated evoked potentials with distinct characteristics in the pallium, subpallial amygdala/ventral pallidum, and dorsal striatopallidum. In the pallium, this sensory activity is generated in the anterior medial region. In the case of olfaction, evoked potentials were recorded at all sites, but displayed different characteristics across telencephalic regions. Stimulation of the anterior dorsal thalamus generated a pattern of activity comparable to olfactory evoked potentials, but it became similar to stimulation of the optic nerve or brainstem after bilateral lesion of the lateral olfactory tract, which interrupted the antidromic activation of the olfactohabenular tract. Intracellular bimodal sensory responses were obtained in the anterior pallium, medial amygdala, ventral pallidum, and dorsal striatopallidum. Our results demonstrate that the amphibian anterior pallium, medial amygdala/ventral pallidum, and dorsal striatopallidum are multimodal sensory centers. The organization of the amphibian telencephalon displays striking similarities with the brain pathways recently implicated in mammalian goal-directed behavior.The Journal of Comparative Neurology 06/2007; 502(1):55-74. · 3.81 Impact Factor -
Article: Organization of the pallium in the fire-bellied toad Bombina orientalis. I: Morphology and axonal projection pattern of neurons revealed by intracellular biocytin labeling.
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ABSTRACT: The cytoarchitecture and axonal projection pattern of pallial areas was studied in the fire-bellied toad Bombina orientalis by intracellular injection of biocytin into a total of 326 neurons forming 204 clusters. Five pallial regions were identified, differing in morphology and projection pattern of neurons. The rostral pallium receiving the bulk of dorsal thalamic afferents has reciprocal connections with all other pallial areas and projects to the septum, nucleus accumbens, and anterior dorsal striatum. The medial pallium projects bilaterally to the medial pallium, septum, nucleus accumbens, mediocentral amygdala, and hypothalamus and ipsilaterally to the rostral, dorsal, and lateral pallium. The ventral part of the medial pallium is distinguished by efferents to the eminentia thalami and the absence of contralateral projections. The dorsal pallium has only ipsilateral projections running to the rostral, medial, and lateral pallium; septum; nucleus accumbens; and eminentia thalami. The lateral pallium has ipsilateral projections to the olfactory bulbs and to the rostral, medial, dorsal, and ventral pallium. The ventral pallium including the striatopallial transition area (SPTA) has ipsilateral projections to the olfactory bulbs, rostral and lateral pallium, dorsal striatopallidum, vomeronasal amygdala, and hypothalamus. The medial pallium can be tentatively homologized with the mammalian hippocampal formation, the dorsal pallium with allocortical areas, the lateral pallium rostrally with the piriform and caudally with the entorhinal cortex, the ventral pallium with the accessory olfactory amygdala. The rostral pallium, with its projections to the dorsal and ventral striatopallidum, resembles the mammalian frontal cortex.The Journal of Comparative Neurology 04/2007; 501(3):443-64. · 3.81 Impact Factor -
Article: Zur Ontogenese aggressiven Verhaltens
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ABSTRACT: In diesem Artikel werden nach der Definition der Begriffe tiologische Anstze zur Entstehung von Gewalt referiert. Zur Frage der Ursachen gewaltttigen Verhaltens liegen umfangreiche Untersuchungen in den Sozialwissenschaften, der Psychologie, der Psychotherapie und der (Neuro-)Biologie bzw. Physiologie vor, ohne dass die jeweiligen Forschungsergebnisse und die daraus resultierenden Erkenntnisse bislang zusammengefhrt und zu einem Gesamtbild vereinigt werden konnten. Der aktuelle Kenntnisstand lautet, dass bei individueller krperlicher Gewalt genetische, physiologische, entwicklungs- und persnlichkeitspsychologische, familire sowie soziale Faktoren ineinandergreifen. Entsprechend sind auch Interventionen zur Eindmmung von Gewalt mehrdimensional auszurichten.The present article reviews current etiological approaches to the origin of violence. In a wide range of empirical research ample results have been found on the causes of violence in many different disciplines like social sciences, psychology, psychotherapy, and neurobiology/neurophysiology. However, an integrative view is still missing. Current knowledge suggests a complex interaction of genetic, physiological, developmental psychological, personality-related, familial and social factors in shaping an individuals disposition to engage in physical violence. Accordingly, interventions for reducing violence have to be multidimensional in nature.Psychotherapeut 02/2007; 52(2):87-101. · 0.36 Impact Factor -
Article: Evolution of the amygdala: new insights from studies in amphibians.
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ABSTRACT: The histology of amphibian brains gives an impression of relative simplicity when compared with that of reptiles or mammals. The amphibian telencephalon is small and contains comparatively few and large neurons, which in most parts constitute a dense periventricular cellular layer. However, the view emerging from the last decade is that the brains of all tetrapods, including amphibians, share a general bauplan resulting from common ancestry and the need to perform similar vital functions. To what extent this common organization also applies to higher brain functions is unknown due to a limited knowledge of the neurobiology of early vertebrates. The amygdala is widely recognized as a brain center critical for basic forms of emotional learning (e.g., fear conditioning) and its structure in amphibians could suggest how this capacity evolved. A functional systems approach is used here to synthesize the results of our anatomical investigations of the amphibian amygdala. It is proposed that the connectivity of the amphibian telencephalon portends a capacity for multi-modal association in a limbic system largely similar to that of amniote vertebrates. One remarkable exception is the presence of new sensory-associative regions of the amygdala in amniotes: the posterior dorsal ventricular ridge plus lateral nuclei in reptiles and the basolateral complex in mammals. These presumably homologous regions apparently are capable of modulating the phylogenetically older central amygdala and allow more complex forms of emotional learning.Brain Behavior and Evolution 02/2006; 67(4):177-87. · 2.21 Impact Factor -
Article: The septal complex of the fire-bellied toad Bombina orientalis: chemoarchitecture.
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ABSTRACT: In order to investigate whether chemoarchitecture would support the subdivision of the anuran septum based on cytoarchitectonic and hodological studies, we performed enzyme-histochemical detection of NADPH-diaphorase and immunohistological demonstration of choline-acetyl transferase (ChAT), aspartate, calretinin, gamma-aminobutyric acid (GABA), 5-hydroxy-tryptamine, tyrosine hydroxylase, neuropeptide Y (NPY), somatostatin, Leu- and Leu + Met-enkephalin, and substance P in the fire-bellied toad Bombina orientalis. Labeling of cell bodies matched well the previously defined subnuclei: The dorsolateral septal nucleus contains enkephalin-immunoreactive (-ir) and weakly stained GABA-ir neurons; calretinin-ir and weakly labeled GABA-ir neurons are found in the ventrolateral septal nucleus. The medial septal nucleus is characterized by the presence of numerous ChAT-ir and some tyrosine hydroxylase-ir neurons, while the dorsal septal nucleus is outlined by its NPY-ir neurons. Many ChAT-ir and some aspartate-ir and somatostatin-ir neurons are found in the diagonal band of Broca, and the central septal nucleus contains some GABA-ir and ChAT-ir neurons. In contrast, labeled fibers form a pattern which does not match the boundaries of septal subnuclei. Comparing the anuran septal complex with that of other vertebrates reveals that the complexity of the lateral septum has increased during the evolution from anamniote to amniote vertebrates. In spite of this fact, many similarities in chemoarchitecture between anurans and other vertebrates are evident. Some basal septal functions such as involvement in learning and memory formation or inhibition of sexual behavior appear to have persisted during vertebrate evolution.Journal of Chemical Neuroanatomy 02/2006; 31(1):59-76. · 2.43 Impact Factor -
Article: Tatort Gehirn
Gehirn & Geist. 01/2006; -
Chapter: Funktionelle Neuroanatomie des limbischen Systems
12/2005: pages 1-74; -
Article: Connectivity and cytoarchitecture of telencephalic centers in the fire-bellied toad Bombina orientalis.
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ABSTRACT: In the fire-bellied toad Bombina orientalis, the connectivity and cytoarchitecture of telencephalic structures were studied by intracellular, anterograde and retrograde biocytin labelling in order to elucidate the neuronal basis of fear conditioning and context learning in amphibians. Our findings suggest the existence of a central amygdala-bed nucleus of the stria terminalis complex in the caudal mid-ventral telencephalon, a vomeronasal amygdala in the caudolateral ventral telencephalon, an olfactory amygdala in the caudal pole of the telencephalon lateral of the vomeronasal amygdala, and a ventromedially situated "medial" amygdala, which is assumed to be functionally equivalent to the basolateral amygdala of mammals. A ventromedial cellular column forms a nucleus accumbens rostrally and continues caudally into a shell-like ventral pallidum. A lateral column constitutes a dorsal striatum proper rostrally, a dorsal pallidum caudally, and a mixed striato-pallidum at intermediate levels. We conclude that the caudal mediolateral complex consisting of an extended central, vomeronasal and olfactory amygdala of anurans represents the ancestral equivalent of the amygdaloid complex of tetrapods. During the evolution of the mammalian telencephalon, this complex apparently was shifted medially and involuted.Brain Research Bulletin 10/2005; 66(4-6):270-6. · 2.82 Impact Factor
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Institutions
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1991–2012
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Universität Bremen
Bremen, Bremen, Germany
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2005–2006
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Institute of Advanced Study, Berlin
Berlin, Land Berlin, Germany
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