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ABSTRACT: Wat is psycho-educatie? Erik Hoencamp en Judith Haffmans doen een moedige poging deze lastige vraag te beantwoorden in hun
boek ‘Psycho-educatie in de GGz en de verslavingszorg’. Psycho-educatie is een onderdeel van ziektemanagement. Het omvat het
bespreken van ziektesymptomen en hun achtergronden, oorzaken en beloop van de ziekte, behandelmogelijkheden; het voorkómen
van terugval, en hoe de patiënt en zijn verwanten met de gevolgen van de ziekte kunnen omgaan. Zo breed gedefinieerd is psycho-educatie
een onlosmakelijk
Tijdschrift voor Bedrijfs- en Verzekeringsgeneeskunde 04/2012; 17(9):416-417.
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ABSTRACT: It has been well documented that acute tryptophan depletion (ATD) induces symptoms in remitted depressed patients treated with an SSRI. ATD also has effects on cognition, both in patients and in healthy samples. The exact nature of ATD-induced cognitive changes in depression remains unclear. It is also unclear whether cognitive effects can be induced through partial ('low-dose') depletion. The aim of this study is to investigate the differential effects of low-dose and high-dose ATD on emotional information processing and mood in remitted depressed patients. Eighteen remitted depressed patients received high-dose and low-dose ATD in a randomized, double-blind, within-subjects crossover design. Mood was assessed before and after administration of the depletion drink. Five hours after administration, patients conducted tests measuring neutral and emotional information processing. High-dose ATD increased depressive symptoms and induced a temporary depressive 'relapse' in half of the patients. High-dose ATD also decreased the recognition of fear and impaired learning and memory retrieval. The impaired learning occurred only in mood-responders. Low-dose ATD had no effects on mood but speeded the recognition of facial expressions of disgust. Accurate recognition of sad faces at baseline was associated with mood response to ATD. High-dose ATD leads to changes in memory and in the recognition of negative facial expressions in SSRI-treated remitted depressed patients. The effect of low-dose ATD on mood and cognition seems to be quite limited. Emotional information processing at baseline predicts mood-response to ATD.
Journal of Psychopharmacology 03/2008; 22(6):653-62. · 3.04 Impact Factor
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ABSTRACT: The objective of this study was to estimate the prevalence of Seasonal Affective Disorder (SAD) in adults with lifetime Attention-Deficit/Hyperactivity Disorder (ADHD).
Patients eligible for this study had lifetime impairing symptoms of ADHD and a current and/or past co-morbid mood disorder according to their medical record. The Seasonal Pattern Assessment Questionnaire (SPAQ) was administered by a telephone interview to assess seasonality.
The overall rate of SAD in this clinical population of adults with ADHD was estimated at 27%. Females were more at risk to develop SAD than men.
The SPAQ is a screening, not a diagnostic instrument.
SAD symptoms are frequently comorbid with ADHD in adults. These results have clinical relevance for the recognition and treatment of SAD with bright light therapy in adults with ADHD.
Journal of Affective Disorders 05/2006; 91(2-3):251-5. · 3.52 Impact Factor
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British Journal of Psychiatry, 187, 148 - 154 (2005).
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Journal of Psychopharmacology, 19, 267 - 276 (2005).
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Psychiatric Services, 60, 74 - 79 (2009).
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Biological Psychiatry, 60 (5), 507 - 514 (2006).
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Journal of Affective Disorders, 86, 305 - 311 (2005).
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Journal of Psychopharmacology, 22, 653 - 662 (2008).
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Journal of Affective Disorders, 104, 119 - 126 (2007).
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Psychotherapy and Psychosomatics, 76, 289 - 297 (2007).