Hiroshi NOGIMURA

Publications (40)3.74 Total impact

• Article: [Successful thoracoscopic surgery for mediastinal parathyroid tumor with preoperative intravenous methylene blue infusion; report of a case].

  Tsuyoshi Takahashi, Ryo Kobayashi, Hiroshi Nogimura, Takeyuki Hiramatsu, Kazuya Suzuki
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  ABSTRACT: A 56-year-old woman was referred to our hospital presenting high serum levels of calcium (Ca) and intact-parathyroid hormone (PTH) and an anterior mediastinal nodule of 18×13 mm in size on chest computed tomography (CT). Tumor was suspected of a parathyroid tumor. 99mTc-methoxy-isobutylisonitrile( MIBI) scintigram showed abnormal radioactive tracer accumulation in the lesion. 3 ml/kg of methylene blue was administered intravenously an hour before surgery, and the stained tumor was successfully resected by thoracoscopic surgery. Pathological diagnosis was parathyroid hyperplasia. Postoperative course was uneventful and serum levels of Ca and intact-PTH returned to normal ranges.
  Kyobu geka. The Japanese journal of thoracic surgery 03/2013; 66(3):259-61.
• Article: [Clinical study of forty-two patients who underwent resection for pulmonary adenosquamous carcinoma].

  Yasumasa Shundo, Tsuyoshi Takahashi, Toru Itaya, Hiroshi Neyatani, Hisao Sugimura, Yusuke Kita, Hiroshi Nogimura, Ryo Kobayashi, Kazuya Suzuki, Kei Shimizu, Kazuhito Funai, Norihiko Shiiya
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  ABSTRACT: Pulmonary adenosquamous carcinoma is a rare malignant tumor as defined by the Japan Lung Cancer Society Classification. At our institution, of the 1,023 patients who underwent resection for primary lung cancer, 42 (4.0%) had adenosquamous carcinoma. Here, we present the clinical features of this malignant tumor. The male : female ratio was low. Many tumors were located peripherally, and the positive rate for carcinoembryonic antigen (CEA) was 54.8%; these clinical findings were similar to those of adenocarcinoma. On the other hand, many tumors had relatively large diameter, and most of the patients were heavy smokers; these findings were consistent with those of squamous cell carcinoma. Hence, the cases of adenosquamous carcinoma had the characteristics of both adenocarcinoma and squamous cell carcinoma. The prognosis of patients with adenosquamous carcinoma was poorer than those of patients with adenocarcinoma and those with squamous cell carcinoma, irrespective of whether it was stages I or II. Adenosquamous carcinoma is characterized by a highly aggressive biological behavior and a high rate of early metastasis. Therefore, even if the diagnosis is made at an early phase, an aggressive approach, including adjuvant chemotherapy, might be necessary for adenosquamous carcinoma.
  Kyobu geka. The Japanese journal of thoracic surgery 09/2011; 64(10):871-6; discussion 876-9.
• Article: CTLA4Ig-gene transfection inhibits obliterative airway disease in rats.

  Yusuke Kita, Kazuya Suzuki, Hiroshi Nogimura, Tsuyoshi Takahashi, Teruhisa Kazui
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  ABSTRACT: Obliterative airway disease (OAD) is a major cause of long-term morbidity following lung transplantation. Its pathologic characteristics are small-airway inflammation and occlusion by fibrous tissue. However, the pathogenesis is uncertain and therapy is ineffective. This study presents the effects of CTLA4Ig-gene therapy on OAD in heterotopically transplanted rat tracheal allografts. Dark Agouti (DA, RT1a) allografts and Lewis (LEW, RT1l) isografts were transplanted into Lewis recipients. The tracheal graft was transplanted heterotopically into the subcutaneous pocket into the back. Adenoviral vectors (1.0x10(9) pfu) containing the CTLA4Ig-gene (AdCTLA4Ig) or the LacZ-gene (AdLacZ) were injected into the tail vein immediately after grafting. Grafts were harvested and examined after more than 35 days for mononuclear cell infiltration development and lumen occlusion with fibrosis. Fully allogenic DA tracheas, treated with AdCTLA4Ig had significantly lower pathologic scores and infiltrating scores than the control allografts. The pathologic findings of the grafts, treated with AdCTLA4Ig, were very similar to those of the syngeneic grafts. The animals experienced no adverse events during follow-up. No evidence of vector-mediated tissue damage was seen in any graft. Adenoviral vectors containing the CTLA4Ig-gene markedly inhibited the obliteration of the airway lumen. OAD may be associated with T-cell responses against graft tissue and alloimmune injury.
  The Annals of Thoracic Surgery 05/2003; 75(4):1123-7. · 3.74 Impact Factor
• Article: Spontaneous parathyroid adenoma hemorrhage.

  Yasumasa Shundo, Hiroshi Nogimura, Yusuke Kita, Hiroshi Neyatani, Ryo Kobayashi, Hisao Sugimura
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  ABSTRACT: We report a case of spontaneous parathyroid adenoma hemorrhage. A 50-year-old man with a sore throat, and swelling and ecchymosis of the entire anterior neck was found in cervical and chest computed tomography revealed to have a low-density area extending from the parapharyngeal region to below the carina, Suspecting descending necrotizing mediastinitis secondary to a peritonsillar abscess, we conducted mediastinal and cervical drainage, but found no abscess. No evidence was found, either, in bacteriological culture of sputum and pleural effusion. After the hematoma disappeared, cervical ultrasonography indicated parathyroid adenoma. Serum calcium was marginally increased, indicating that serum calcium should be determined if cervical or mediastinal hematoma develops without an obvious cause.
  The Japanese Journal of Thoracic and Cardiovascular Surgery 10/2002; 50(9):391-4.
• Source

  Available from: Teruhisa Kazui

  Article: PS-054-5 当院における特発性縦隔気腫の検討(第2報)(肺嚢胞性疾患6・縦隔気腫, 第24回日本呼吸器外科学会総会号)

  雄介 北, 宏 野木村, 一也 鈴木, 暉 数井, Yusuke KITA, Hiroshi NOGIMURA, Kazuya SUZUKI, Teruhisa Kazui
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  ABSTRACT: rights: 特定非営利活動法人日本呼吸器外科学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110006371330/
• Article: P-121 癌性胸膜炎を伴う肺腺癌の治療に関する臨床的検討

  一也 鈴木, 倫博 堀口, 久雄 杉村, 宏 野木村, 亮 小林, 明望 富井, 幸雄 原田, Kazuya SUZUKI, Tomohiro HORIGUCHI, Hisao SUGIMURA, Hiroshi NOGIMURA, Ryou KOBAYASHI, Meibou TOMII, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003121465/
• Article: 特発性縦隔気腫の3例(症例 (7), 第22回日本呼吸器外科学会総会)

  雄介 北, 宏 野木村, 洋 閨谷, 毅 高橋, 亮 小林, 諭 大井, 晃三 松下, 一也 鈴木, 暉久 数井, Yusuke KITA, Hiroshi NOGIMURA, Hiroshi NEYATANI, Tuyoshi TAKAHASHI, Ryou KOBAYASHI, Satoshi OHI, Kozo MATSUSHITA, Kazuya SUZUKI, Teruhisa Kazui
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  ABSTRACT: rights: 特定非営利活動法人日本呼吸器外科学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110004034645/
• Article: 再発肺癌に対する治療 : FOCAL unit を用いた定位放射線治療(肺癌 (5), 第22回日本呼吸器外科学会総会)

  雄介 北, 宏 野木村, 洋 閨谷, 毅 高橋, 亮 小林, 諭 大井, 晃三 松下, 一也 鈴木, 暉久 数井, Yusuke KITA, Hiroshi NOGIMURA, Hiroshi NEYATANI, Tuyoshi TAKAHASHI, Ryou KOBAYASHI, Satoshi OHI, Kozo MATSUSHITA, Kazuya SUZUKI, Teruhisa Kazui
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  ABSTRACT: rights: 特定非営利活動法人日本呼吸器外科学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110004034304/
• Article: 腫瘍マーカー、proGRPの臨床的有用性

  雄介 北, 善彦 影山, 宏 野木村, 一也 鈴木, 幸雄 原田, 啓史 早川, 金吾 千田, 篤彦 佐藤, 諭 大井, 倫博 堀口, Yusuke KITA, Yoshihiko KAGEYAMA, Hiroshi NOGIMURA, Kazuya SUZUKI, Yukio HARADA, Hiroshi Hayakawa, Kingo Chida, Atsuhiko SATO, Satoshi OHI, Tomohiro HORIGUCHI
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003139822/
• Article: 17 胸腔内腫瘤性病変に対する胸腔鏡の有用性

  善彦 影山, 一也 鈴木, 宏 野木村, 亮 小林, 太 豊田, 幸雄 原田, 篤彦 佐藤, Yoshihiko KAGEYAMA, Kazuya SUZUKI, Hiroshi NOGIMURA, Ryou KOBAYASHI, Futoru TOYODA, Yukio HARADA, Atsuhiko SATO
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003142940/
• Article: 胸腔鏡を利用した区域切除 : 胸腔鏡下手術1

  一也 鈴木, 諭 大井, 雄介 北, 善彦 影山, 太 豊田, 宏 野木村, 幸雄 原田, Kazuya SUZUKI, Satoshi OHI, Yusuke KITA, Yoshihiko KAGEYAMA, Futoru TOYODA, Hiroshi NOGIMURA, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003134348/
• Article: P-376 非小細胞肺癌の試験開胸例の検討

  亮 小林, 太 豊田, 宏 野木村, 一也 鈴木, 幸雄 原田, Ryou KOBAYASHI, Futoru TOYODA, Hiroshi NOGIMURA, Kazuya SUZUKI, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003125877/
• Article: P-194 肺癌脳転移例の検討

  太 豊田, 一也 鈴木, 宏 野木村, 亮 小林, 幸雄 原田, 哲夫 西村, 昌生 金子, Futoru TOYODA, Kazuya SUZUKI, Hiroshi NOGIMURA, Ryou KOBAYASHI, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003125695/
• Article: Ga-12 I期、II期肺癌手術後1年以内再発死亡例の検討

  一也 鈴木, 倫博 堀口, 宏 野木村, 亮 小林, 幸雄 原田, 洋 閨谷, Kazuya SUZUKI, Tomohiro HORIGUCHI, Hiroshi NOGIMURA, Ryou KOBAYASHI, Yukio HARADA, Hiroshi NEYATANI
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003122441/
• Article: CDDPを含む肺癌化学療法の副作用対策としてのMPA(Medroxyprogesterone Acetate)投与の有用性に関する検討

  一也 鈴木, 宏 野木村, 倫博 堀口, 久雄 杉村, 隆久 伴野, 幸雄 原田, Kazuya SUZUKI, Hiroshi NOGIMURA, Tomohiro HORIGUCHI, Hisao SUGIMURA, Takahisa TOMONO, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003132958/
• Article: P-249 高齢者肺癌の検討

  太 豊田, 善彦 影山, 宏 野木村, 亮 小林, 一也 鈴木, 幸雄 原田, Futoru TOYODA, Yoshihiko KAGEYAMA, Hiroshi NOGIMURA, Ryou KOBAYASHI, Kazuya SUZUKI, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003143427/
• Article: 癌性心嚢炎に対する局所療法の検討

  久雄 杉村, 宏 野木村, 倫博 堀口, 隆久 伴野, 一也 鈴木, 幸雄 原田, Hisao SUGIMURA, Hiroshi NOGIMURA, Tomohiro HORIGUCHI, Takahisa TOMONO, Kazuya SUZUKI, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003132614/
• Article: 245 当院におけるLaser治療症例の検討

  倫博 堀口, 明望 富井, 宏 野木村, 亮 小林, 久雄 杉村, 隆久 伴野, 一也 鈴木, 幸雄 原田, Tomohiro HORIGUCHI, Meibou TOMII, Hiroshi NOGIMURA, Ryou KOBAYASHI, Hisao SUGIMURA, Takahisa TOMONO, Kazuya SUZUKI, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003121174/
• Article: P-220 飾骨洞にatypical chondroid tumorを合併した胸腺扁平上皮癌の1例

  明望 富井, 一也 鈴木, 倫博 堀口, 久雄 杉村, 宏 野木村, 亮 小林, 幸雄 原田, Meibou TOMII, Kazuya SUZUKI, Tomohiro HORIGUCHI, Hisao SUGIMURA, Hiroshi NOGIMURA, Ryou KOBAYASHI, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003121564/
• Article: P-126 術中温熱化学療法の試み

  善彦 影山, 一也 鈴木, 宏 野木村, 亮 小林, 太 豊田, 幸雄 原田, Yoshihiko KAGEYAMA, Kazuya SUZUKI, Hiroshi NOGIMURA, Ryou KOBAYASHI, Futoru TOYODA, Yukio HARADA
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  ABSTRACT: rights: 日本肺癌学会 rights: 本文データは学協会の許諾に基づきCiNiiから複製したものである relation：isVersionOf: http://ci.nii.ac.jp/naid/110003143304/