Publications (7)7.35 Total impact
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Conference Proceeding: Investigation of the correlation between heart rate and heart rate variability
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ABSTRACT: Pathologic conditions are frequently associated with marked changes in heart rate (HR), which itself influences its variability (HRV). Accordingly, some researchers consider the HR and the HRV to be equivalent measures. The question was posed: Does the HRV afford different information than the HR itself? The HRV were investigated in ten patients during a normal autonomic tone and a pharmacological autonomic blockade, respectively. The results were analysed by calculation of the product-moment correlation coefficient and by means of linear regression of the HRV and the HR. Significant correlations were found between the HR and all of the HRV bands. The regression coefficients of the HR and HRV increased markedly after a sympathetic blockade. The extent of the regression decreased to nearly zero during a total vegetative blockade. It was concluded that (1) There is a significant negative correlation between the HR and the HRV; (2) The degree of this connection is influenced markedly by the actual tone of the autonomic nervous system, which means different information contents of the HR and its variability in the autonomic regulation of the circulation.Computers in Cardiology 1995; 10/1995 -
Article: 964 Parallel evaluation of coronary flow velocity reserve and elastic moduli of the descending aorta in hypertensive patients with normal epicardial coronary arteries
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Article: 965 Coronary flow velocity reserve and aortic distensibility indices in patients with untreated hypercholesterolaemia with a negative coronary angiogram
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Article: 915 Correlation between aortic distensibility and body weight in obesity -- a transthoracic echocardiographic study
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Article: Alcohol-induced congestive cardiomyopathy in adult turkeys: effects on myocardial antioxidant defence systems.
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ABSTRACT: The effects of chronic intake of dietary alcohol upon left ventricular function, activities of myocardial antioxidant enzymes, reduced glutathione (GSH) content and lipoperoxidation (measured as the formation of diene conjugates and lipid-soluble fluorescence) were studied in adult domestic Nicholas turkeys. The non-invasive evaluation of left ventricular function by echocardiography revealed an impaired contractile function (the calculated fractional shortening values were 31.1 +/- 4.1% in the alcoholic group and 38.8 +/- 4.4% in the controls) and dilatation of the heart in the alcoholic birds. The changes in the non-invasive parameters of the left ventricle indicate that the adult Nicholas turkey developed congestive cardiomyopathy secondary to the ingestion of ethanol. In the hearts of normal adult turkeys, high GSH content (2.39 +/- 0.25 mumol/g wet weight) and superoxide dismutase activity were found, as compared to other animals, indicating the relatively higher development of antioxidant defence systems. Compared to the controls, significant increases were noted for all the antioxidant enzymes investigated (superoxide dismutase, catalase and glutathione peroxidase) and a moderately significant decrease in the GSH content was found in the left ventricle of alcoholic birds. The changes in GSH concentration and antioxidant enzyme activities might indirectly indicate some involvement of free radicals in the pathogenesis of ethanol-induced myocardial lesion. However, the levels of in vivo lipoperoxidation in the alcoholic birds did not significantly vary from those of control turkeys. Based on these findings, it appears that the reactive oxygen radicals may play a less important role in the pathogenesis of alcohol-induced cardiomyopathy in turkeys--probably due to the higher development of myocardial antioxidant defence systems.Archiv für Kreislaufforschung 82(6):551-6. · 7.35 Impact Factor -
Article: 699 Obesity is associated with aortic enlargement and increased stiffness
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Article: 714 Diabetes mellitus facilitates aortic stiffening in acromegaly
