Jasmina Alibegovic

University of Geneva, Genève, Geneva, Switzerland

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Publications (4)6.9 Total impact

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    ABSTRACT: The occurrence of atrial fibrillation after percutaneous closure of a patent foramen ovale for cryptogenic stroke has been reported in a variable percentage of patients. However, its precise incidence and mechanism are presently unclear and remain to be elucidated. Prospective follow-up study. Ninety-two patients undergoing a percutaneous patent foramen ovale closure procedure (closure group) for cryptogenic stroke were compared with a similar group of 51 patients, who were medically treated. A systematic arrhythmia follow-up protocol to assess the incidence of AF was performed including a 7-day event-loop recording at day 1, after 6 and 12 months in patients of the closure group and compared with those of the medically treated group. The incidence of AF was similar in both study groups during a follow-up of 12 months, including 7.6% (95% CI: 3.1-15.0%) in the closure and 7.8% (95% CI: 2.18-18.9%) in the medically treated group (P=1.0). The presence of a large patent foramen ovale was the only significant risk factor for the occurrence of AF as demonstrated by a multivariate Cox regression analysis (95% CI, 1.275-20.018; P=0.021). Our findings indicate that patients with cryptogenic stroke and patent foramen ovale have a rather high incidence of AF during a follow-up of 12 months. Atrial fibrillation occurred with a similar frequency whether the patent foramen ovale/atrial septal defect was successfully percutaneously closed or was medically managed. The presence of a large patent foramen ovale was the only significant predictor of AF occurrence during follow-up.
    International Journal of Stroke 02/2010; 5(1):4-9. DOI:10.1111/j.1747-4949.2009.00336.x · 4.03 Impact Factor
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    ABSTRACT: Myocardial bridge (MB) or tunneled coronary artery is an inborn abnormality, which implicates a systolic vessel compression with a persistent mid-late diastolic diameter reduction. Myocardial bridges are often observed during coronary angiography with an incidence of 0.5%-5.5%. The most involved coronary artery is the left anterior descending artery followed by the diagonal branches, the right coronary artery, and the left circumflex. The overall long-term prognosis is generally benign. However, several risk or precipitating factors (e.g., high heart rate, left ventricular hypertrophy, decreased peripheral vascular resistance) may trigger symptoms (most frequently angina). Herein, we describe two cases of symptomatic myocardial bridge, where medical treatment (i.e., inotropic negative drug) and coronary stenting were successfully utilized to treat this pathology. We also focus on the clinical presentation, and the diagnostic and therapeutic modalities to correctly manage this frequently observed congenital coronary abnormality, underlining the fact that in cases of typical angina symptoms without any significant coronary artery disease, MB should be considered as a possible differential diagnosis.
    Heart and Vessels 02/2008; 23(1):67-70. DOI:10.1007/s00380-007-1011-z · 2.11 Impact Factor
  • Source
    J Alibegovic · Rf Bonvini · U Sigwart · Pa Dorsaz · E Camenzind · V Verin
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    ABSTRACT: To find a correlation between the patent foramen ovale (PFO) size measured by the sizing balloon and the appropriate closure device size. The PFO of 57 patients was closed using a sizing balloon. A mathematical model was introduced to relate the PFO balloon waist diameter to the closure device size based on the PFO transformation from a slit-like to a circular form during balloon inflation. According to this model, PFOs smaller than 8 mm should be closed with a 25 mm device, PFOs 8 mm to 11 mm with a 35 mm device, and PFOs larger than 11 mm with an Amplatzer septal occluder. In the first group, 36 patients (63.2%) received an appropriately sized device and six patients (10.5%) received an oversized device. In the second group, 15 patients (26.3%) received an undersized device. A comparison of the PFO dimensions in two views showed that the PFO slit was circular when the balloon was inflated. A six-month echocardiography follow-up was obtained in 46 patients (80.7%). Five patients (13.9%) in the group with an appropriately sized device had a discrete residual shunt during Valsalva. In the second group, five patients (33.3%) had a residual shunt (P = 0.06), of which one was considered large. The sizing balloon is helpful in selecting the PFO closure device size. Consequently, the incidence of residual shunt and recurrent events may be reduced.
    Experimental and clinical cardiology 01/2008; 13(1):42-6. · 0.76 Impact Factor
  • Taoufik Hendiri · Jasmina Alibegovic · Robert F Bonvini · Edoardo Camenzind
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    ABSTRACT: A 48-year-old woman was admitted for an acute infero-lateral myocardial infarction (AMI). The coronary angiography showed an occluded aberrant left circumflex artery taking off from the right sinus of Valsalva of the aortic root. This rare coronary anomaly represents a challenge for interventional cardiologists, especially in the setting of AMI, since it may be difficult to identify an aberrant occluded vessel, to predict its origin and course and finally to choose the material which offers an adequate support during the revascularization procedure. In this particular case, the percutaneous treatment of initially occluded aberrant circumflex artery was performed successfully.
    Acute Cardiac Care 02/2006; 8(2):125-7. DOI:10.1080/17482940600767717