Publications (4)10.15 Total impact
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Article: Plastic protein microarray to investigate the molecular pathways of magnetic nanoparticle-induced nanotoxicity.
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ABSTRACT: Superparamagnetic iron oxide nanoparticles (SPIONs) (about 15 nm) were synthesized via a hydrothermal method and characterized by field emission scanning electron microscopy, transmission electron microscopy, dynamic light scattering, x-ray diffraction, and vibrating sample magnetometer. The molecular pathways of SPIONs-induced nanotoxicity was further investigated by protein microarrays on a plastic substrate from evaluation of cell viability, reactive oxygen species (ROS) generation and cell apoptosis. The experimental results reveal that 50 μg ml(-1) or higher levels of SPIONs cause significant loss of cell viability, considerable generation of ROS and cell apoptosis. It is proposed that high level SPIONs could induce cell apoptosis via a mitochondria-mediated intrinsic pathway by activation of caspase 9 and caspase 3, an increase of the Bax/Bcl-2 ratio, and down-regulation of HSP70 and HSP90 survivor factors.Nanotechnology 04/2013; 24(17):175501. · 3.98 Impact Factor -
Article: Enhancement of photoelectric response of bacteriorhodopsin by multilayered WO3 x H2O nanocrystals/PVA membrane.
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ABSTRACT: For the first time, a multilayered WO(3) x H(2)O/PVA membrane on bacteriorhodopsin (bR) is constructed to significantly enhance the photoelectric response of bR by the spillover effect of WO(3) x H(2)O nanocrystals, providing great potential in its important applications in bioelectronics and proton exchange membrane fuel cells.Chemical Communications 02/2010; 46(5):689-91. · 6.17 Impact Factor -
Article: Supercapacitance of Solid Carbon Nanofibers Made from Ethanol Flames
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ABSTRACT: Solid carbon nanofibers (CNFs) made from ethanol flames were used to prepare supercapacitors. Their microstructure, crystallinity, porosity, chemical properties, and electrochemical activity were compared with the multiwalled carbon nanotubes (MWCNTs) synthesized by chemical vapor deposition. The produced CNFs have a unique microstructure with a solid core and porous surface. The specific surface area of CNFs was comparable to that of MWCNTs because of their larger amount of micropores on the surface. The synthesis environment also resulted in abundant functional groups absorbed on the surface of the CNFs. Electrochemical characterization shows that CNFs have much larger capacitance than that of MWCNTs. The capacitance of CNFs consists of both double-layer capacitance contributed by micropores and pseudo-capacitance produced from redox reactions of the absorbed oxygen functional groups. In comparison to the reported MWCNTs-based supercapacitors, the CNF demonstrates more promising potential in energy storage applications because of its larger electrochemical capacitance.02/2008; -
Article: Lithium Insertion in Channel-Structured β-AgVO3: In Situ Raman Study and Computer Simulation
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ABSTRACT: Lithium insertion is the fundamental electrochemical process of rechargeable lithium batteries. We report here in situ Raman and atomistic simulation studies of the lithium insertion process in β-AgVO3 nanowired structure material. Key issues of the process relate to structural variations and lithium migration pathways in the β-AgVO3. The simulation model shows good agreement with the experimental results. It indicates that the lithium insertion can be divided into three steps. The reduction sites at each step in the β-AgVO3 lattice are confirmed: the most favorable reduction sites at higher potential are V1/V4; at medium potential, Ag2/Ag3 are reduced and substituted; after that Li+ ion reduces V2/V3/Ag4 and further reduces V1/V4. The migration pathways of Li+ ions in β-AgVO3 are proposed for the first time. Our discovery would help us to greatly understand the deep insight of the Li+ insertion process in lithium batteries.11/2007;
