R Bussar-Maatz

Publications (2)1.41 Total impact

• Article: Klinische Studien außerhalb von Universitätskliniken

  U. Zurbuchen, W. Schwenk, R. Bussar-Maatz, F. Wichlas, H.-J. Buhr, J. Neudecker, J.-P. Ritz
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  ABSTRACT: Die Forderung nach hochwertiger evidenzbasierter Therapie in der operativen Medizin in Deutschland und das Bewusstsein über die meist erheblich mangelhafte Qualität der chirurgischen Studien macht die Notwendigkeit von randomisiert-kontrollierten Studien deutlich. In 6 öffentlich geförderten operativen Studienzentren wird seit 2006 an der Schaffung einer professionellen Infrastruktur für chirurgische Studien gearbeitet. Ziel ist die Initiierung chirurgischer Multicenterstudien, die durch regionale Vernetzung effektiv durchgeführt werden können. Um eine zeitgerechte Patientenrekrutierung in diesen Studien zu sichern, ist es essenziell, in Zukunft nichtuniversitäre chirurgische Kliniken in die Studiendurchführung zu integrieren. Mithilfe einer Fragebogenaktion in nichtuniversitären chirurgischen Kliniken in Berlin und Brandenburg wurden das Interesse, die Studienerfahrungen und die strukturellen Gegebenheiten in diesen Kliniken evaluiert. Der vorliegende Beitrag diskutiert anhand der Ergebnisse dieser Umfrage, wie zukünftig nichtuniversitäre chirurgische Kliniken in die aktive Studiendurchführung eingebunden werden können und wie zu einer hohen Patientenrekrutierung motiviert werden kann. The demand for high quality evidence-based surgical treatment in Germany and awareness of the poor quality of surgical trials highlight the basic necessity of randomized controlled trials. In six surgical trial centers a professional infrastructure for surgical trials is in the process of being established since 2006.The aim is the initiation of surgical multicenter trials which can be effectively conducted by local networking. To accomplish a timely recruitment of patients it is necessary to integrate surgical departments outside university hospitals into multicenter trials. With a questionnaire survey of non-university surgical departments in the federal states of Berlin and Brandenburg, interest, experience in clinical trials and structural conditions in these departments were evaluated. Based on the results of this survey the possibilities to integrate non-university surgical departments into multicenter trials and how a high recruitment of patients can be motivated will be discussed in this article.
  Der Chirurg 05/2012; 81(2):160-166. · 0.70 Impact Factor
• Article: [Clinical studies outside university clinics : What are the problems to implement this?].

  U Zurbuchen, W Schwenk, R Bussar-Maatz, F Wichlas, H-J Buhr, J Neudecker, J-P Ritz
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  ABSTRACT: The demand for high quality evidence-based surgical treatment in Germany and awareness of the poor quality of surgical trials highlight the basic necessity of randomized controlled trials. In six surgical trial centers a professional infrastructure for surgical trials is in the process of being established since 2006.The aim is the initiation of surgical multicenter trials which can be effectively conducted by local networking. To accomplish a timely recruitment of patients it is necessary to integrate surgical departments outside university hospitals into multicenter trials. With a questionnaire survey of non-university surgical departments in the federal states of Berlin and Brandenburg, interest, experience in clinical trials and structural conditions in these departments were evaluated. Based on the results of this survey the possibilities to integrate non-university surgical departments into multicenter trials and how a high recruitment of patients can be motivated will be discussed in this article.
  Der Chirurg 12/2009; 81(2):160; 162-6. · 0.70 Impact Factor