E. Kostka

Friedrich-Schiller-University Jena, Jena, Thuringia, Germany

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Publications (6)4.5 Total impact

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    ABSTRACT: Zusammenfassung Von einer 73-jährigen Patientin wurden rechtsseitige Gesichtsschmerzen, eine progrediente Hörminderung, Drehschwindel bei Lagewechsel, eine präaurikuläre Schwellung und mangelnde Mimik angegeben. Klinisch bestand in der rechten Temporalregion eine indolente, nicht verschiebliche Raumforderung von etwa 7 cm Größe sowie eine inkomplette ipsilaterale akute periphere Fazialisparese. Magnetresonanztomographisch zeigten sich eine etwa 75 mm durchmessende Raumforderung rechts temporal sowie multilokuläre Filiae in Becken, Wirbelsäule, Klavikula und Schädelkalotte. Histologisch lag ein gut bis mäßig differenziertes Adenokarzinom vor mit fokal positiver Immunantwort auf GCDFP-24 („gross cystic disease fluid protein“). In der daraufhin veranlassten Computertomographie des Thorax und die Mammographie stellte sich der etwa 25 mm große Primärtumor in der linken Brust dar. Nach Operation und Radiatio lautete die TNM-Klassifikation: tubuläres Adenokarzinom der Mamma links, G2 (Grading 2), T2N0M1 [OSS (multipel ossär), BRA (Brain)], Stadium IV.
    HNO 01/2011; 59(12). DOI:10.1007/s00106-009-2010-4 · 0.58 Impact Factor
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    ABSTRACT: A 73-year-old female patient complained of right-sided facial pain, progressive loss of hearing, giddiness when changing position, a pre-auricular swelling and lack of facial expression. Clinically there was a right-sided indolent and immovable swelling approximately 7 cm in size and an incomplete ipsilateral acute peripheral facial paralysis. Magnetic resonance tomography revealed a space-occupying lesion approximately 75 mm in diameter right temporal and multilocular metastases in the pelvis, spinal column, clavicle and skull. Histology showed this to be a well to moderately differentiated adenocarcinoma with centers of positive immune response to GCDFP-24 (gross cystic disease fluid protein). The subsequent computed tomography of the thorax and mammography located the approximately 25 mm in size primary tumor in the left breast. After surgery and radiation therapy the TNM classification was a tubular adenocarcinoma of the left breast grade 2, T2N0M1 (OSS multiple osseous, BRA brain) stage IV.
    HNO 12/2010; 59(12):1219-23. · 0.58 Impact Factor
  • Laryngo-Rhino-Otologie 01/2010; 89(01):36-38. DOI:10.1055/s-0029-1237709 · 0.84 Impact Factor
  • Laryngo-Rhino-Otologie 10/2009; 89(1):36-8. · 0.84 Impact Factor
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    ABSTRACT: The tongue is said to be the mirror of physical health. The tongue dorsum is most delicate regarding the sense of touch. Pathologic coating of the tongue accounts for paresthesia during chewing, swallowing, speaking, tasting, and also may result in mouth odor. Tongue coating can result from increased formation or decreased natural abrasion, and from xerostomia or dyschylia. In clinical otorhinolaryngology pathologic tongue coating often is idiopathic or present after surgery of the oral cavity or pharynx. Critical analysis of published studies reveals that effectivity and justification to administer xenobiotics or vitamins in that condition is doubtful. Recently, it has been shown that tongue fur was able to be reduced by an easy-to-handle mechanical tongue cleaner or tongue scraper. Due to its simple use, tongue scrapers could be a welcome supplement for the treatment of tongue fur, mouth odor, and in particular cases, to enhance gustatory sense. Preliminary results of an ongoing prospective trial showed that tongue scrapers can effectively be applied after surgery of the oral cavity or pharynx. After tonsillectomy, tongue fur seemed to be reduced and gustatory sense to be enhanced when tongue scrapers were applied during postoperative care. After confirming these promising results in further investigations, an inexpensive and simple option for the treatment of a large amount of patients in clinical otorhinolaryngology would exist.
    Laryngo-Rhino-Otologie 08/2008; 87(8):546-50. · 0.84 Impact Factor
  • Laryngo-Rhino-Otologie 08/2008; 87(08):546-550. DOI:10.1055/s-2007-995614 · 0.84 Impact Factor