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ABSTRACT: Du 6 juillet au 29 septembre 2009, 380 patients ont consulté pour syndrome grippal et 355 dossiers (253 femmes, 102 hommes)
ont été analysés rétrospectivement. La moyenne d’âge était de 32 ans. Cent cinquante-huit patients, dont 22 avec grippe A(H1N1)2009,
présentaient un terrain à risque: grossesse (n = 87), asthme (n = 37), obésité (n = 17). Les symptômes les plus fréquents des patients avec grippe A(H1N1)2009 étaient: fièvre (97 % des patients), toux (94
%), rhinorrhée (59 %), myalgies (56 %), céphalées (36 %). Un prélèvement nasopharyngé pour recherche de virus grippal par
PCR a été réalisé chez 118 patients, dont 27 femmes enceintes. Le résultat était positif pour 44 patients, dont 40 cas de
grippe A(H1N1)2009. Vingt et un patients ont été adressés aux urgences pour bilan complémentaire ou traitement et 31 patients
ont été hospitalisés. Vingt femmes enceintes ont été adressées en milieu obstétrical pour monitoring cardiaque foetal; aucune
n’a présenté de détresse respiratoire ou de signe de souffrance foetale. Aucun patient vu en consultation dédiée n’a été admis
en réanimation ou n’est décédé.
From July 6 to September 29, 2009, 380 patients were seen as out-patients for flu-like illness, and 355 files (253 women and
102 men) were available for retrospective analysis. Mean age was 32 years. 158 patients, including 22 with A(H1N1)2009 influenza
had underlying medical conditions: pregnancy (N = 87), asthma (N = 37), obesity (N = 17). Most frequent symptoms of A(H1N1)2009 influenza patients were fever (97% of the patients), cough (94%), rhinorrhea
(59%), myalgia (56%), headache (36%). A nasopharyngeal swab for influenza virus detection by PCR was performed on 118 patients
including 27 pregnant women. 44 patients, including 40 A(H1N1)2009 influenza cases were tested positive. 21 patients were
referred to the emergency department for further tests or treatment and 31 patients were admitted as in-patients. 20 pregnant
women were referred for further obstetrical monitoring; none presented with respiratory failure or foetal distress. None of
the patients were admitted to the ICU or died.
Mots clésGrippe A(H1N1)2009–Facteurs de risque–Grossesse–Évolution–Île de la Réunion
KeywordsA(H1N1)2009 influenza–Risk factors–Pregnancy–Outcome–Réunion Island
Bulletin de la Société de pathologie exotique 04/2012; 104(2):142-146.
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ABSTRACT: From July 6 to September 29, 2009, 380 patients were seen as out-patients for flu-like illness, and 355 files (253 women and 102 men) were available for retrospective analysis. Mean age was 32 years. 158 patients, including 22 with A(H1N1)2009 influenza had underlying medical conditions: pregnancy (N = 87), asthma (N = 37), obesity (N = 17). Most frequent symptoms of A(H1N1)2009 influenza patients were fever (97% of the patients), cough (94%), rhinorrhea (59%), myalgia (56%), headache (36%). A nasopharyngeal swab for influenza virus detection by PCR was performed on 118 patients including 27 pregnant women. 44 patients, including 40 A(H1N1)2009 influenza cases were tested positive. 21 patients were referred to the emergency department for further tests or treatment and 31 patients were admitted as in-patients. 20 pregnant women were referred for further obstetrical monitoring; none presented with respiratory failure or foetal distress. None of the patients were admitted to the ICU or died.
Bulletin de la Société de pathologie exotique 05/2011; 104(2):142-6.
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ABSTRACT: The antibiotic resistance of enterobacteriacae knows a worldwide worrying evolution with an increase of the extended spectrum betalactamases (ESBL) that spread into the community. Few publications describe this problem in the Indian Ocean area. The aim of this study is first to identify in Félix Guyon Hospital (Reunion Island) the emergent antibiotics resistance for enterobacteriaceae between 1997/1998 and 2006/2007 periods, at second, to update the prophylactic and therapeutic measures for handling the risk linked to multiresistant enterobacteriaceae in our hospital and third, to assess the risk in Reunion Island and especially at the community level.
The antibiotic susceptibility of 7814 enterobacteriaceae strains collected among patients, during 1997/1998 and 2006/2007 periods, were analysed as well as the consumption of the third generation cephalosporins, imipenem and fluoroquinolones.
Within a span of time of 10 years, an important increase (+57 %) of the resistance prevalence of enterobacteriaceae is observed. The resistance by the ESBL production mechanism is predominant especially for Enterobacter cloacae and Escherichia coli. An important use of broad spectrum antibiotics is correlated with this resistance evolution.
The emergence of ESBL-producing enterobacteriaceae in our hospital is impairing both therapeutic and health care. It requires a much better control of antibiotics prescriptions and therefore, an important multidisciplinary implication. A proof molecular analysis would allow to evaluate the risk more precisely, especially at the community level.
Pathologie Biologie 10/2009; 58(1):18-24. · 1.53 Impact Factor