Ai-Guo Zhong

Publications (4)19.57 Total impact

• Article: Chiral squaramides as highly enantioselective catalysts for Michael addition reactions of 4-hydroxycoumarins and 4-hydroxypyrone to beta,gamma-unsaturated alpha-keto esters.

  Dan-Qian Xu, Yi-Feng Wang, Wei Zhang, Shu-Ping Luo, Ai-Guo Zhong, Ai-Bao Xia, Zhen-Yuan Xu
  Chemistry 03/2010; 16(14):4177-80. · 5.93 Impact Factor
• Article: Enantioselective Michael Addition of Aromatic Ketones to Nitroolefins Catalyzed by Bifunctional Thioureas and Mechanistic Insight

  Bai-Lin Li, Yi-Feng Wang, Shu-Ping Luo, Ai-Guo Zhong, Zhao-Bo Li, Xiao-Hua Du, Dan-Qian Xu
  Annalen der Chemie und Pharmacie 12/2009; 2010(4):656 - 662. · 3.10 Impact Factor
• Article: One-pot organocatalytic asymmetric synthesis of 3-nitro-1,2-dihydroquinolines by a dual-activation protocol.

  Yi-Feng Wang, Wei Zhang, Shu-Ping Luo, Bai-Lin Li, Ai-Bao Xia, Ai-Guo Zhong, Dan-Qian Xu
  [show abstract] [hide abstract]
  ABSTRACT: Generally, amine-catalyzed enantioselective transformations rely on chiral enamine or unsaturated iminium intermediates. Herein, we report a protocol involving dual activation by an aromatic iminium and hydrogen-bonding. An enantioselective aza-Michael-Henry domino reaction of 2-aminobenzaldehydes with nitroolefins has been developed through this protocol using primary amine thiourea catalysts to provide a variety of 3-nitro-1,2-dihydroquinolines in moderate yields and with up to 90% ee. The mechanism for the catalytic enantioselective reaction was confirmed by ESI mass spectrometric detection of the reaction intermediates. The products formed are substructures found in skeletons of important biological and pharmaceutical molecules.
  Chemistry - An Asian Journal 10/2009; 4(12):1834-8. · 4.50 Impact Factor
• Article: A Novel Enantioselective Catalytic Tandem Oxa‐Michael–Henry Reaction: One‐Pot Organocatalytic Asymmetric Synthesis of 3‐Nitro‐2H‐chromenes

  Dan-Qian Xu, Yi-Feng Wang, Shu-Ping Luo, Shuai Zhang, Ai-Guo Zhong, Hui Chen, Zhen-Yuan Xu
  Advanced Synthesis & Catalysis 11/2008; 350(16):2610 - 2616. · 6.05 Impact Factor