Sang Woo Kim

Catholic University of Korea, Sŏul, Seoul, South Korea

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Publications (324)674.45 Total impact

  • [Show abstract] [Hide abstract]
    ABSTRACT: Affine projection sign algorithm (APSA) is a useful adaptive filter for a highly correlated input signal in the presence of impulsive noise. In this study, a novel variable step-size APSA is proposed using selective input vectors to achieve both fast convergence rate and low steady-state mean-square deviation (MSD) with low computational cost. The selective input vectors and step size are chosen so as to maximize the theoretical MSD difference derived using Price׳s theorem. The simulation results show that the proposed algorithm has the fastest convergence rate and lowest steady-state MSD when compared with recent variable step-size APSAs. Moreover, it effectively reduces computational cost.
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    ABSTRACT: We report the fabrication of nickel nanofiber catalysts supported on nickel metallic foam using a modified electrospinning with a grounded rotor and sequential reduction process. The robust deposition of aligned Ni nanofibers with a uniform morphology on the highly porous surfaces of the metallic foam could be achieved by controlling electrospinning parameters such as applied voltage, tip-collector-distance (TCD), concentration of polymer, and humidity. The diameters of the obtained nanofibers decreased with increasing voltage and TCDs. The uniform and thinnest Ni nanofibers on the Ni foam were obtained at a humidity of less than 30%, 15 kV applied voltage, and 17 cm TCD when using a precursor composed of nickel nitrate salt and poly(vinyl) pyrrolidone. The Ni foam catalyst support exhibited the superior thermal conducting property than other supports of MgO–MgAl2O4, Al2 O3, and SiC, enabling to a higher heat transfer during catalytic reaction. As a result, the Ni nanofiber catalyst with a high surface area and superior heat transfer performance, which is supported on the metallic foam, were successfully fabricated via a modified electrospinning for potential application of XTL process converting anything to liquids, such as for Gas-to-Liquid (GTL), Coal-to-Liquid (CTL), and Biomass-to-Liquid (BTL).
    Journal of Nanoscience and Nanotechnology 07/2015; 15(7). DOI:10.1166/jnn.2015.10414 · 1.34 Impact Factor
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    ABSTRACT: For afternoon colonoscopy, same-day administration of sodium picosulfate, magnesium oxide, and citric acid (PM/Ca) is recommended. However, few studies have evaluated the bowel-cleansing efficacy and safety of this regimen. The aim of this study was to compare the bowel-cleansing efficacy, side effects, and patient's tolerability of a same-day split administration of PM/Ca with polyethylene glycol (PEG) for afternoon colonoscopy.Patients were randomly assigned to a PM/Ca group or a PEG group. The PM/Ca group consumed 1 sachet of PM/Ca at 06:00 and 1 sachet of PM/Ca 4 hours before the colonoscopy. They also took 2 tablets of bisacodyl before sleep on the night before. The PEG group consumed 2 L of PEG at 06:00 and 2 L of PEG 4 hours before the colonoscopy. All subjects were instructed to finish the bowel cleanser or fluid at least 2 hours before colonoscopy. All colonoscopic examinations were performed in the afternoon on the same day. The bowel-cleansing efficacy was scored using 2 scales: the Ottawa Bowel Preparation Scale (OBPS) and the Aronchick scale. Ease of using the bowel cleanser was rated from 1 (very easy) to 5 (very difficult).Two hundred nine patients underwent colonoscopy. The bowel-cleansing scores by OBPS did not differ between groups (5.0 vs 4.9, P = 0.63). Ease of using the bowel cleanser was superior in the PM/Ca group (P < 0.01).The cleansing efficacy of PM/Ca administered on the day of colonoscopy is comparable to that of PEG. Patients prefer PM/Ca.
    Medicine 04/2015; 94(13):e628. DOI:10.1097/MD.0000000000000628 · 4.87 Impact Factor
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    ABSTRACT: One of the most interesting issues in obesity research is why certain humans are obesity-prone (OP) while others are obesity-resistant (OR) upon exposure to a high-calorie diet. However, the pathways responsible for these phenotypic differences are still largely unknown. In order to discover marker molecules determining susceptibility and/or resistance to obesity in response to high fat diet (HFD) or anti-obesity herbal medicine (TH), we conducted comparative proteomic analysis of white adipose tissue (WAT) from OP, OR, as well as TH-treated mice. OP mice fed HFD gained approximately 33% more body weight than OR mice, and TH significantly reduced body weight gain in HFD-fed mice by 30%. These mice were further subjected to proteomic analysis using two-dimensional electrophoresis (2-DE) combined with matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS). Proteomic data revealed 59 spots that were differentially regulated from a total of 1,045 matched spots, and 57 spots of these were identified as altered WAT proteins between OP and OR mice by peptide mass finger printing. Interestingly, 45 proteins were similarly regulated in OR mice in response to TH treatment. Of these, 10 proteins have already been recognized in the context of obesity; however, other proteins involved in obesity susceptibility or resistance were identified for the first time in the present study. Our results suggest that TH actively contributed to body weight reduction in HFD-fed obese mice by altering protein regulation in WAT, and it was also found that TH-responsive proteins can be used as potent molecules for obesity treatment. © 2015 S. Karger AG, Basel.
    Cellular Physiology and Biochemistry 03/2015; 35(4):1482-1498. DOI:10.1159/000373967 · 3.55 Impact Factor
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    Ikchan Jeon, Sang Woo Kim
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    ABSTRACT: Posterior vertebral translation as a type of spondylolisthesis, retrolisthesis is observed commonly in patients with degenerative spinal problems. Nevertheless, there is insufficient literature on retrolisthesis compared to anterolisthesis. The purpose of this study is to clarify the clinical features of retrolisthesis, and its developmental mechanism associated with a compensatory role in sagittal imbalance of the lumbar spine. From 2003 to 2012, 230 Korean patients who underwent spinal surgery in our department under the impression of degenerative lumbar spinal disease were enrolled. All participants were divided into four groups : 35 patients with retrolisthesis (group R), 32 patients with simultaneous retrolisthesis and anterolisthesis (group R+A), 76 patients with anterolisthesis (group A), and 87 patients with non-translation (group N). The clinical features and the sagittal parameters related to retrolisthesis were retrospectively analyzed based on the patients' medical records. There were different clinical features and developmental mechanisms between retrolisthesis and anterolisthesis. The location of retrolisthesis was affected by the presence of simultaneous anterolisthesis, even though it predominantly manifest in L3. The relative lower pelvic incidence, pelvic tilt, and lumbar lordosis compared to anterolisthesis were related to the generation of retrolisthesis, with the opposite observations of patients with anterolisthesis. Retrolisthesis acts as a compensatory mechanism for moving the gravity axis posteriorly for sagittal imbalance in the lumbar spine under low pelvic incidence and insufficient intra-spinal compensation.
    Journal of Korean Neurosurgical Society 03/2015; 57(3):178-84. DOI:10.3340/jkns.2015.57.3.178 · 0.52 Impact Factor
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    ABSTRACT: Regulation of DJ1 is associated with a number of human diseases. To determine the involvement of DJ1 in progression of diabetes in a gender-dependent manner, we investigated its tissue-specific expression in streptozotocin (STZ)-induced diabetic male and female rats in this study. In animal experiments, females showed greater susceptibility towards developing diabetes because of lower insulin secretion and higher blood glucose levels as compared to male diabetic rats upon exposure to STZ. Immunoblotting confirmed sexually dimorphic regulation of DJ1 in various metabolic tissues such as the liver, pancreas and skeletal muscle. Immunofluorescence analysis revealed the location as well as reinforced the gender-dependent expression of DJ1 in hepatic tissue. Co-immunoprecipitation assay identified several interacting proteins with DJ1 whose functions were shown to be involved in various metabolic pathways viz. antioxidative and stress defence system, protein and methionine metabolism, nitrogen metabolism, urea metabolism, etc. Using GeneMANIA, a predictive web interface for gene functions, we showed for the first time that DJ1 may regulate T1DM via the JNK1 pathway, suggesting DJ1 interacts with other proteins from various metabolic pathways. We anticipate that the current data will provide insights into the aetiology of T1DM. © 2015 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.
    Journal of Cellular and Molecular Medicine 02/2015; DOI:10.1111/jcmm.12490 · 3.70 Impact Factor
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    ABSTRACT: Traumatic diaphragm hernia can occur in rare cases and generally accompanies thoracic or abdominal injuries. When suffering from ankylosing spondylitis, a small force can develop into vertebral fracture and an adjacent structural injury, and lead to diaphragm hernia without accompanying concomitant thoracoabdominal injury. A high level of suspicion may be a most reliable diagnostic tool in the detection of a diaphragm injury, and we need to keep in mind a possibility in a patient with ankylosing spondylitis and a thoracolumbar fracture, even in the case of minor trauma.
    Journal of Korean Neurosurgical Society 02/2015; 57(2):131-4. DOI:10.3340/jkns.2015.57.2.131 · 0.52 Impact Factor
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    Su Jin Hong, Sang Woo Kim
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    ABSTRACT: Helicobacter pylori infection, a common infection in many countries, is related to the clinical course of upper gastrointestinal diseases. Gastroesophageal reflux disease (GERD) is a common esophageal disease in Western countries and its prevalence is increasing in Asian countries. The pathophysiology of GERD is multifactorial. Although no single factor has been isolated as the cause of GERD, a negative association between the prevalence of H. pylori and the severity of GERD, including Barrett's esophagus, has been demonstrated in epidemiological studies. The high prevalence of H. pylori infection affects the incidence of GERD in Asian countries. In the subjects with East Asian CagA-positive strains, acid injury may be minimized by hypochlorhydria from pangastritis and gastric atrophy. Additionally, host genetic factors may affect the development of GERD. The interactions between genetic factors and the virulence of H. pylori infection may be the reason for the low prevalence of GERD in Asian countries. H. pylori eradication is not considered pivotal in GERD exacerbation based on evidence from Western studies. A recent meta-analysis demonstrated that eradication therapy of H. pylori was related to a higher risk of developing de novo GERD in Asian studies. H. pylori infection remains an inconclusive and important issue in GERD in Asian countries.
    Gastroenterology Research and Practice 01/2015; 2015:985249. DOI:10.1155/2015/985249 · 1.50 Impact Factor
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    ABSTRACT: A new minimization criterion for the normalized subband adaptive filter (NSAF), which is called improved NSAF (INSAF), was introduced recently to improve the performance of the steady-state mean-square deviation (MSD). However, the steady-state MSD analysis of the INSAF was not studied. Therefore, this paper proposes a general solution of steady-sate MSD analysis of the INSAF algorithm, which is based on the substitution of the past weight error vector in the weight error vector. The simulation shows that our theoretical results correspond closely with the computer simulation results in various environments.
    Signal Processing 01/2015; 106:49–54. DOI:10.1016/j.sigpro.2014.06.026 · 2.24 Impact Factor
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    ABSTRACT: A series of Cu–ZnO–Al2O3 catalysts were prepared by coprecipitation method. The pH of solution was adjusted from 6 to 8 by using Na2CO3 solution. The prepared catalysts were evaluated for methanol synthesis from syngas (H2, CO and CO2) at lower temperature and pressures. Catalysts have been characterized by N2 physisorption, porosity measurements, XRD, TG/DTA, TPD (CO2/NH3) and XPS. Among all the catalysts pH 7 catalyst was shown higher catalytic activity towards methanol formation. It was found that the catalyst is mainly possessed the higher number of surface active sites (Cu0/Cu+), acidic and basic nature and optimum synergism between three components (Cu–ZnO–Al2O3). The activity results were evaluated with and without CO2 in syngas and it was found that higher CO conversion and higher methanol selectivity in the presence CO2.
    Journal of Nanoscience and Nanotechnology 01/2015; 15(1). DOI:10.1166/jnn.2015.8352 · 1.34 Impact Factor
  • Sang Woo Kim, Hyun-seok Choi, Kyung-sub Lee
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    ABSTRACT: In this work, we investigate the thermal conductivity of a three-component composite consisting of FeCr metal core-aluminum oxide shell particles with a highly mesoporous shell layer. This composite showed highly enhanced thermal conductivity compared to typical two-component composites consisting of uni-modal particles. The improved thermal conductivity was found to be the result of excellent thermal contact conductance through the shell layer between the core particle surface and the continuous polymer medium. There was no effect from the enhancement of the thermal conductivity in the shell layer itself because the predicted thermal conductivity of the shell layer is significantly reduced by phonon scattering at the boundaries of the nanocrystals of a size less than a phonon mean free path in the alumina in the shell layer containing a columnar-like pore morphology. The thermal conductivity of the three-component composites containing core-shell particles with a nanostructured shell layer was well predicted from the modified core-shell percolation theory, which considered the effects of phonon scattering and pores.
    Materials Research Bulletin 12/2014; 60:843-848. DOI:10.1016/j.materresbull.2014.09.079 · 1.97 Impact Factor
  • Advanced Functional Materials 11/2014; 24(44). DOI:10.1002/adfm.201470288 · 10.44 Impact Factor
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    ABSTRACT: Remarkable enhancement of piezoelectric power output from a nanogenerator (NG) based on a zinc oxide (ZnO) thin film is achieved via native defect control. A large number of unintentionally induced point defects that act as n-type carriers in ZnO have a strong influence on screening the piezoelectric potential into a piezoelectric NG. Here, additional oxygen molecules bombarded into ZnO lead to oxygen-rich conditions, and the n-type conductivity of ZnO is decreased dramatically. The acceptor-type point defects such as zinc vacancies created during the deposition process trap n-type carriers occurring from donor-type point defects through a self-compensation mechanism. This unique insulating-type ZnO thin film-based NGs (IZ-NGs) generates output voltage around 1.5 V that is over ten times higher than that of an n-type ZnO thin film-based NG (around 0.1 V). In addition, it is found that the power output performance of the IZ-NG can be further increased by hybridizing with a p-type polymer (poly(3-hexylthiophene-2,5-diyl):phenyl-C61-butyric acid methyl ester) via surface free carrier neutralization.
    Advanced Functional Materials 11/2014; 24(44). DOI:10.1002/adfm.201401998 · 10.44 Impact Factor
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    ABSTRACT: To overcome the performance degradation of least mean square (LMS)-type algorithms when input signals are correlated, the normalized subband adaptive filter (NSAF) was developed. In the NSAF, the regularization parameter influences the stability and performance. In addition, there is a trade-off between convergence rate and steady-state mean square deviation (MSD) according to the change of the parameter. Therefore, to achieve both fast convergence rate and low steady-state MSD, the parameter should be varied. In this paper, a variable regularization scheme for the NSAF is derived on the basis of the orthogonality between the weight-error vector and weight vector update, and by using the calculated MSD. The performance of the variable regularization algorithm is evaluated in terms of MSD. Our simulation results exhibit fast convergence and low steady-state MSD when using the proposed algorithm.
    Signal Processing 11/2014; 104:432–436. DOI:10.1016/j.sigpro.2014.04.036 · 2.24 Impact Factor
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    ABSTRACT: Unintentionally formed nanocrystalline graphene (nc-G) can act as a useful seed for the large-area synthesis of a hexagonal boron nitride (h-BN) thin film with an atomically flat surface that is comparable to that of exfoliated single-crystal h-BN. A wafer-scale dielectric h-BN thin film was successfully synthesized on a bare sapphire substrate by assistance of nc-G, which prevented structural deformations in a chemical vapor deposition process. The growth mechanism of this nc-G-tailored h-BN thin film was systematically analyzed. This approach provides a novel method for preparing high-quality two-dimensional materials on a large surface.
    Angewandte Chemie 10/2014; 126(43). DOI:10.1002/ange.201405762
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    ABSTRACT: Unintentionally formed nanocrystalline graphene (nc-G) can act as a useful seed for the large-area synthesis of a hexagonal boron nitride (h-BN) thin film with an atomically flat surface that is comparable to that of exfoliated single-crystal h-BN. A wafer-scale dielectric h-BN thin film was successfully synthesized on a bare sapphire substrate by assistance of nc-G, which prevented structural deformations in a chemical vapor deposition process. The growth mechanism of this nc-G-tailored h-BN thin film was systematically analyzed. This approach provides a novel method for preparing high-quality two-dimensional materials on a large surface.
    Angewandte Chemie International Edition 10/2014; 53(43). DOI:10.1002/anie.201405762 · 11.34 Impact Factor
  • Sang Woo Kim, Kyoung Joo Cho
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    ABSTRACT: Fragile X syndrome (FXS), the most common cause of inherited human mental retardation, results from the loss of function of fragile X mental retardation protein (FMRP). To date, most researchers have thought that FXS neural pathologies are primarily caused by extreme dendritic branching and spine formation. With this rationale, several researchers attempted to prune dendritic branches and reduce the number of spines in FXS animal models. We propose that increased dendritic arborization and spinogenesis in FXS are developed rather as secondary compensatory responses to counteract the compromised postsynaptic activity during uncontrollable metabotropic glutamate receptor (mGluR)-dependent long-term depression (LTD). When postsynaptic and electrical activities become dampened in FXS, dendritic trees can increase their sensitivity to brain-derived neurotrophic factor (BDNF) by using the molecular sensor called eukaryotic elongation factor 2 (eEF2) and taking advantage of the tight coupling of mGluR and BDNF-TrkB signaling pathways. Then, this activity-dependent elevation of the BDNF signaling can strategically alter dendritic morphologies to foster branching and develop spine structures in order to improve the postsynaptic response in FXS. Our model suggests a new therapeutic rationale for FXS: correcting the postsynaptic and electrical activity first, and then repairing structural abnormalities of dendrites. Then, it may be possible to successfully fix the dendritic morphologies without affecting the survival of neurons. Our theory may also be generalized to explain aberrant dendritic structures observed in other neurobehavioral diseases, such as tuberous sclerosis, Rett syndrome, schizophrenia, and channelopathies, which accompany high postsynaptic and electrical activity.
    Medical Hypotheses 10/2014; 83(4). DOI:10.1016/j.mehy.2014.07.007 · 1.15 Impact Factor
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    Ik Chan Jeon, Sang Woo Kim, Young Jin Jung
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    ABSTRACT: The causes of sciatica are variable and include musculoskeletal, dermatologic, infectious, neoplastic, and vascular disorders. In many cases, the symptom is usually caused by degenerative disease in the spine with the compression or irritation of spinal nerve. On the other hands, there are also several announced extra-spinal causes including aneurysm, diabetes, and radiation for sciatica in a low rate. Among the extra-spinal cases, aneurysms arising from iliac vessels are sometimes developing a diagnostic confusion with the spinal causes, and delayed diagnosis can lead to poor prognosis. It is very important to pay attention weather the aneurysmal cause is involved in the symptom of sciatica.
    The Korean journal of pain 10/2014; 27(4):360-4. DOI:10.3344/kjp.2014.27.4.360
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    ABSTRACT: Perovskite nanoparticle-based nanocomposite thin films strictly tailored using unconventional layer-by-layer (LbL) assembly in organic media for piezoelectric nanogenerators (NGs) are demonstrated. By employing sub-20-nm BaTiO3 nanoparticles stabilized by oleic acid ligands (i.e., OA-BTONPs) and carboxylic acid (COOH)-functionalized polymers, such as poly(acrylic acid) (PAA), the resulting OA-BTONP/PAA nanocomposite multilayers are prepared by exploiting the high affinity between the COOH groups of PAA and the BTONPs. The ferroelectric and piezoelectric performance of the (PAA/OA-BTONP)n thin films can be precisely controlled by altering the bilayer number, inserted polymer type, and OA-BTONP size. It is found that the LbL assembly in nonpolar solvent media can effectively increase the quantity of adsorbed OA-BTONPs, resulting in the dramatic enhancement of electric power output from the piezoelectric NGs. Furthermore, very low leakage currents are detected from the (PAA/OA-BTONP)n thin films for obtaining highly reliable power-generating performance of piezoelectric NGs.
    Advanced Functional Materials 10/2014; 24(40). DOI:10.1002/adfm.201401599 · 10.44 Impact Factor
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    ABSTRACT: Bowel preparation with sodium phosphate was recently prohibited by the U.S. Food and Drug Administration. Polyethylene glycol (PEG) is safe and effective; however, it is difficult to drink. To identify an easy bowel preparation method for colonoscopy, we evaluated three different bowel preparation regimens regarding their efficacy and patient satisfaction.
    10/2014; 30(5):222-7. DOI:10.3393/ac.2014.30.5.222

Publication Stats

3k Citations
674.45 Total Impact Points


  • 2010–2015
    • Catholic University of Korea
      • • Department of Internal Medicine
      • • College of Medicine
      Sŏul, Seoul, South Korea
    • POSCO E&C
      Urusan, Ulsan, South Korea
  • 2009–2015
    • Yeungnam University
      • Department of Neurosurgery
      Gyeongsan, Gyeongsangbuk-do, South Korea
    • Seoul Veterans Hospital
      Sŏul, Seoul, South Korea
    • Pusan National University
      Tsau-liang-hai, Busan, South Korea
    • Howard Hughes Medical Institute
      Ashburn, Virginia, United States
    • Kyungpook National University Hospital
      Sŏul, Seoul, South Korea
  • 2002–2015
    • Daegu University
      • Department of Biotechnology
      Daikyū, Daegu, South Korea
  • 1992–2015
    • Pohang University of Science and Technology
      • • Department of Electronic and Electrical Engineering
      • • Department of Electrical and Computer Engineering
      Geijitsu, North Gyeongsang, South Korea
  • 2014
    • Gyeongsang National University
      Shinshū, Gyeongsangnam-do, South Korea
    • Kongju National University
      • Division of Advanced Materials Engineering
      Gongju, Chungcheongnam-do, South Korea
  • 2013–2014
    • Brown University
      • Department of Neuroscience
      Providence, Rhode Island, United States
    • Yonsei University
      • Department of Chemical and Biomolecular Engineering
      Sŏul, Seoul, South Korea
  • 2012–2014
    • Sungkyunkwan University
      • School of Advanced Materials Science and Engineering (AMSE)
      Sŏul, Seoul, South Korea
    • Gyeongnam National University of Science and Technology
      Sŏul, Seoul, South Korea
  • 2010–2014
    • University of Ulsan
      • College of Medicine
      Urusan, Ulsan, South Korea
  • 2009–2014
    • Ulsan University Hospital
      Urusan, Ulsan, South Korea
  • 2004–2014
    • Korea Institute of Science and Technology
      • • Clean Energy Research Center
      • • High Temperature Energy Materials Research Center
      Sŏul, Seoul, South Korea
    • Hankuk University of Foreign Studies
      • Department of Chemistry
      Sŏul, Seoul, South Korea
  • 2009–2013
    • Kangwon National University
      • Department of Applied Plant Sciences
      Kang-neung, Gangwon, South Korea
  • 2009–2012
    • University of Pittsburgh
      • Department of Computational & Systems Biology
      Pittsburgh, PA, United States
  • 2011
    • Chonnam National University
      • Department of Pathology
      Gwangju, Gwangju, South Korea
  • 2008–2010
    • Chung-Ang University
      • College of Pharmacy
      Sŏul, Seoul, South Korea
    • Chosun University
      • Department of Advanced Materials Engineering
      Gwangju, Gwangju, South Korea
    • Chonbuk National University
      • School of Medicine
      Seoul, Seoul, South Korea
  • 2005–2010
    • Inje University Paik Hospital
      • Department of Pediatrics
      Sŏul, Seoul, South Korea
    • Kyungpook National University
      • Advanced Display Manufacturing Research Center
      Daikyū, Daegu, South Korea
  • 2007–2008
    • Yonsei University Hospital
      • Department of Internal Medicine
      Sŏul, Seoul, South Korea
    • Dongguk University
      Sŏul, Seoul, South Korea
    • Dong-A University
      • Department of Electronics Engineering
      Tsau-liang-hai, Busan, South Korea
  • 2005–2008
    • Inje University
      • College of Medicine
      Kŭmhae, Gyeongsangnam-do, South Korea
  • 2002–2008
    • Chungnam National University
      • Department of Chemical Engineering
      Sŏngnam, Gyeonggi Province, South Korea
  • 2005–2006
    • Chungbuk National University
      • Department of Electronic Engineering
      Chinsen, Chungcheongbuk-do, South Korea
  • 1989–2003
    • Seoul National University
      Sŏul, Seoul, South Korea
  • 2001
    • Korea Advanced Institute of Science and Technology
      • Department of Chemistry
      Seoul, Seoul, South Korea
    • Hannam University
      • Department of Chemistry
      Daiden, Daejeon, South Korea
  • 1996
    • Korea University
      • Department of Materials Science and Engineering
      Seoul, Seoul, South Korea