-
[show abstract]
[hide abstract]
ABSTRACT: Zenker diverticulum is known as an adult disease which occurs as result of outpouching of pharyngeal mucosa through a weak zone in the posterior wall of the pharynx. It is a very rare disorder in childhood, and only a few pediatric cases of Zenker diverticulum have been reported. Here, we report a 10-year-old boy with Zenker diverticulum who presented with aspiration pneumonia, dysphagia, regurgitation, and halitosis. The radiologic evaluation of the patient included chest radiography, ultrasonography, esophagography, and chest computed tomography which clearly demonstrated the pathological findings and confirmed the diagnosis.
Diagnostic and interventional radiology (Ankara, Turkey) 10/2009; 15(3):207-9. · 1.10 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: To investigate the effects of blocking prenatal androgen with the anti-androgen flutamide on testicular weight (TW), seminiferous tubular diameter (STD), testicular biopsy score (TBS), testicular testosterone (TT), and fertility.
Ten pregnant Wistar albino rats were injected with flutamide (100 mg/kg) on gestational days 16 and 19. Rats injected with the solvent were used as controls. Male pups from these dams were evaluated for testicular descent on postnatal day 22. The ability of each male to produce offspring was tested when the animals were aged 130 days. The rats were killed when 180 days old, and the testes were removed.
Sixteen of the 24 male rats (66.6%) exhibited cryptorchidism (6 unilateral, 10 bilateral) in the flutamide-treated group. Three of the rats with normally descended testicles were fertile, but none of the cryptorchid rats was fertile in flutamide-treated group. The average TW, mean STD, TBS and TT levels of the flutamide-treated rats was significantly lower than in the solvent-injected rats. However, there was no significant difference in these values between descended and undescended testes in flutamide-treated rats.
Blocking of prenatal androgen with flutamide interferes with testicular development by inhibiting testicular descent, and also effects testicular morphology and function in both the descended and undescended testes of rats.
Urologia Internationalis 02/2006; 76(2):130-3. · 0.99 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: Congenital megalourethra is a rare congenital malformation of the penile urethra. It is defined as the diffuse dilatation of the anterior urethra due to the absence of development of the erectile tissue of the penis. Since the initial description, nearly 80 cases with megalourethra have been reported in English literature. Congenital megalourethra has been classified into scaphoid and fusiform types and is usually associated with additional urinary tract and other system anomalies, irrespective of its type and severity. We report two rare cases of scaphoid megalourethra without any associated anomaly. A 13-year-old boy and an 8-month-old boy were admitted to the Department of Pediatric Surgery with complaints of penile swelling and dysuria since birth. Physical examination and retrograde cystourethrogram confirmed the diagnosis of congenital scaphoid megalourethra. Both patients underwent a reduction urethroplasty. They did well postoperatively and voided with a normal stream without any abnormality of the penile shaft.
International Journal of Urology 05/2005; 12(4):419-21. · 1.75 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: This study was undertaken to investigate the effects of bupivacaine on beta-endorphin (BE) and cortisol (C) release and postoperative pain in children. Thirty children aged 1 month to 2 years undergoing outpatient inguinal hernia under general anesthesia were randomized into three groups. Wound infiltration in group 1 patients (precisional group) was performed with 0.5 ml/ kg 0.25% bupivacaine following anesthesia induction but prior to surgery. Group 2 patients (postincisional group) had wound infiltration with bupivacaine following repair of the hernia but before skin closure. Group 3 patients (control group) did not receive any local anesthetic. In the post-anesthesia care unit (PACU) objective pain assessments were performed every 5 min using a standardized ten-point objective pain scale. Plasma C concentrations increased at the end of the operation in all groups, but this increase was significant only in the control group (P < 0.001).="" there="" was="" no="" significant="" difference="" between="" the="" pre-="" and="" postincisional="" groups="" with="" regard="" to="" pre-="" and="" postoperative="" c="" alterations="">P > 0.05). Although plasma BE concentrations increased significantly at the end of the operation in the control group (P < 0.001),="" no="" significant="" difference="" was="" found="" between="" pre-="" and="" postoperative="" values="" in="" the="" infiltration="" groups.="" there="" was="" a="" more="" marked="" difference="" in="" be="" release="" between="" the="" preincisional="" and="" control="" groups="">P < 0.001)="" than="" the="" postincisional="" group="">P < 0.05).="" although="" the="" objective="" pain="" scores="" were="" not="" statistically="" different="" upon="" pacu="" arrival,="" the="" patients="" in="" the="" infiltration="" groups="" achieved="" a="" pain="" score="" of="" 0="" much="" more="" quickly="" than="" those="" in="" the="" control="" group="">P < 0.05).="" these="" findings="" suggest="" that="" wound="" infiltration="" with="" bupivacaine="" decreases="" the="" stress="" response="" to="" surgery="" and="" postoperative="">
Pediatric Surgery International 12/1995; 11(1):41-44. · 1.25 Impact Factor
-
[show abstract]
[hide abstract]
ABSTRACT: Bronchogenic cysts are relatively uncommon congenital lesions. Because of the variability in clinical presentation and the shortcomings of diagnostic procedures, bronchogenic cysts present a diagnostic problem. This report describes a giant bronchogenic cyst that presented as a lobar emphysema in a newborn.
The Annals of Thoracic Surgery.
