Publications (3)13.48 Total impact
-
Article: Next-generation sequencing of Coccidioides immitis isolated during cluster investigation.
[show abstract] [hide abstract]
ABSTRACT: Next-generation sequencing enables use of whole-genome sequence typing (WGST) as a viable and discriminatory tool for genotyping and molecular epidemiologic analysis. We used WGST to confirm the linkage of a cluster of Coccidioides immitis isolates from 3 patients who received organ transplants from a single donor who later had positive test results for coccidioidomycosis. Isolates from the 3 patients were nearly genetically identical (a total of 3 single-nucleotide polymorphisms identified among them), thereby demonstrating direct descent of the 3 isolates from an original isolate. We used WGST to demonstrate the genotypic relatedness of C. immitis isolates that were also epidemiologically linked. Thus, WGST offers unique benefits to public health for investigation of clusters considered to be linked to a single source.Emerging Infectious Diseases 02/2011; 17(2):227-32. · 6.79 Impact Factor -
Article: Hospital methicillin-resistant Staphylococcus aureus active surveillance practices in Los Angeles County: Implications of legislation-based infection control, 2008.
[show abstract] [hide abstract]
ABSTRACT: Pending California legislation prompted an on-line survey of methicillin-resistant Staphylococcus aureus (MRSA) active surveillance practices administered to infection preventionists of all 102 acute care licensed hospitals in Los Angeles County. We describe reported surveillance methods. Ninety-six hospitals responded with 41% performing MRSA active surveillance. Comments indicated resistance to implementation of active surveillance because its benefits remain controversial.American journal of infection control 10/2010; 38(8):653-6. · 3.01 Impact Factor -
Article: Pseudo-outbreak of respiratory syncytial virus infection in a neonatal intensive care unit due to cross-reactivity of surfactant and a rapid immunoassay.
[show abstract] [hide abstract]
ABSTRACT: We describe a pseudo-outbreak of respiratory syncytial virus infection in a neonatal intensive care unit at the White Memorial Medical Center in Los Angeles, California. Investigation of a reported cluster of cases in the early fall of 2007 identified false-positive results due to cross-reactivity between surfactant and a rapid immunoassay. This highlights the need for diagnosis confirmation, especially during periods of low disease prevalence.Infection Control and Hospital Epidemiology 10/2009; 30(9):890-2. · 3.67 Impact Factor
Top Journals
Institutions
-
2010
-
County of Los Angeles Public Health
Los Angeles, CA, USA
-